SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 8 ILE A 129
VAL A 284
GLY A 175
LEU A 179
 None
 0.97A 1dzmA-4y7pA:
1.3		 1dzmA-4y7pA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 9 LEU A  85
ILE A 199
PHE A  79
GLY A 297
PHE A 262
 None
 1.04A 1td7A-4y7pA:
undetectable		 1td7A-4y7pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 10 GLU A 196
GLU A 193
ASN A 189
LEU A 203
LEU A 205
 None
 1.39A 2ha6A-4y7pA:
undetectable		 2ha6A-4y7pA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 10 GLU A 196
GLU A 193
ASN A 189
LEU A 203
LEU A 205
 None
 1.34A 2ha6B-4y7pA:
undetectable		 2ha6B-4y7pA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 6 TYR A 171
TRP A 169
TYR A 176
GLN A 121
 None
 1.45A 2pgzD-4y7pA:
undetectable
2pgzE-4y7pA:
undetectable		 2pgzD-4y7pA:
19.28
2pgzE-4y7pA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 6 ILE A  38
ILE A 217
LEU A  31
PHE A  35
 None
 0.99A 3adsA-4y7pA:
undetectable		 3adsA-4y7pA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 7 ILE A  38
ILE A 217
LEU A  31
PHE A  35
 None
 0.98A 3adxA-4y7pA:
undetectable		 3adxA-4y7pA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 12 LEU A  85
LEU A 272
LEU A 266
ALA A  81
THR A  78
 None
 0.98A 3r9cA-4y7pA:
undetectable		 3r9cA-4y7pA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 4 GLY A  73
GLY A 314
THR A 321
LEU A 259
 None
 0.81A 3si7C-4y7pA:
undetectable
3si7D-4y7pA:
undetectable		 3si7C-4y7pA:
21.54
3si7D-4y7pA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 12 LEU A 123
ILE A 119
VAL A 106
LEU A 178
VAL A 153
 None
 1.04A 4gc9A-4y7pA:
undetectable		 4gc9A-4y7pA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.81A 4k8cA-4y7pA:
undetectable		 4k8cA-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.83A 4kahA-4y7pA:
undetectable		 4kahA-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.82A 4kahB-4y7pA:
undetectable		 4kahB-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.83A 4kanA-4y7pA:
undetectable		 4kanA-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.81A 4kanB-4y7pA:
undetectable		 4kanB-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.82A 4kbeA-4y7pA:
undetectable		 4kbeA-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.81A 4kbeB-4y7pA:
undetectable		 4kbeB-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.82A 4lbgA-4y7pA:
undetectable		 4lbgA-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		3 / 3 SER A 215
TYR A 240
PRO A 211
 None
 0.83A 4lbgB-4y7pA:
undetectable		 4lbgB-4y7pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 12 GLY A 297
ILE A 298
THR A 283
VAL A 284
LEU A 267
 None
 1.32A 5nz0A-4y7pA:
undetectable		 5nz0A-4y7pA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 6 PHE A  70
LEU A 337
ARG A  71
GLY A 318
 None
 1.12A 5o4yF-4y7pA:
undetectable		 5o4yF-4y7pA:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 12 GLY A 325
THR A 326
GLY A 329
THR A  78
ASN A 260
 None
 0.89A 5ybbA-4y7pA:
undetectable		 5ybbA-4y7pA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 5 ALA A 149
SER A 247
GLY A 246
TYR A 132
 None
 1.22A 5yodB-4y7pA:
undetectable		 5yodB-4y7pA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 5 ALA A 149
SER A 247
GLY A 246
TYR A 132
 None
 1.24A 5yodD-4y7pA:
undetectable		 5yodD-4y7pA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 6 ARG A  71
SER A 215
THR A 143
VAL A 238
 None
 1.22A 5ysiA-4y7pA:
undetectable		 5ysiA-4y7pA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		5 / 12 TYR A 132
PHE A 163
ALA A 149
THR A  80
LEU A 122
 None
 1.22A 6aybA-4y7pA:
undetectable		 6aybA-4y7pA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4y7p ALKALINE D-PEPTIDASE
(Bacillus
cereus) 		4 / 7 GLY A 175
TYR A 176
ASN A 124
GLY A 297
 None
 0.94A 6n7fA-4y7pA:
undetectable		 6n7fA-4y7pA:
12.43