SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 7 LEU M  27
GLU M  40
LEU M  42
TYR M 185
 None
 0.98A 2w8yA-4y82M:
undetectable		 2w8yA-4y82M:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 4 LEU M 184
ARG M 156
LEU M 155
ALA M 148
 None
 0.97A 3b9mA-4y82M:
undetectable		 3b9mA-4y82M:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 11 VAL M  50
ALA M 117
GLY M 118
ALA M 173
TYR M  16
 None
 1.29A 3qxyB-4y82M:
undetectable
3qxyQ-4y82M:
undetectable		 3qxyB-4y82M:
20.67
3qxyQ-4y82M:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		6 / 12 PHE M 146
ILE M 177
GLY M 147
SER M  10
ALA M  24
ALA M  23
 None
 1.32A 3sufB-4y82M:
undetectable		 3sufB-4y82M:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 4 GLN M 171
VAL M 170
GLU M 174
ILE M 199
 None
 0.86A 5jncA-4y82M:
undetectable		 5jncA-4y82M:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 9 ALA M 198
ILE M  43
GLY M  52
ILE M 115
PRO M  89
 None
 1.29A 5kr2C-4y82M:
undetectable		 5kr2C-4y82M:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 12 VAL M 170
ILE M 177
ILE M 199
LEU M 155
VAL M 158
 None
 0.97A 6ajiA-4y82M:
undetectable		 6ajiA-4y82M:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 4y82 PROTEASOME SUBUNIT
BETA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 12 PHE M 146
ILE M 177
GLY M 147
SER M  10
ALA M  24
 None
 1.21A 6c2mB-4y82M:
undetectable		 6c2mB-4y82M:
15.57