SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4y96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 1dz4A-4y96A:
undetectable		 1dz4A-4y96A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 1dz4B-4y96A:
undetectable		 1dz4B-4y96A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 5 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 1dz6B-4y96A:
undetectable		 1dz6B-4y96A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		3 / 3 ALA A 190
HIS A 191
VAL A 194
 None
 0.37A 1lqtB-4y96A:
undetectable		 1lqtB-4y96A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		3 / 3 ALA A 190
HIS A 191
VAL A 194
 None
 0.38A 1lquB-4y96A:
undetectable		 1lquB-4y96A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.92A 1o76B-4y96A:
undetectable		 1o76B-4y96A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.99A 1p7rA-4y96A:
undetectable		 1p7rA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.93A 1t85A-4y96A:
undetectable		 1t85A-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.90A 1t87A-4y96A:
undetectable		 1t87A-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.91A 1t88A-4y96A:
undetectable		 1t88A-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 5 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.92A 1t88B-4y96A:
undetectable		 1t88B-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 1yrcA-4y96A:
undetectable		 1yrcA-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 1yrdA-4y96A:
undetectable		 1yrdA-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.95A 2cppA-4y96A:
undetectable		 2cppA-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 2feuA-4y96A:
undetectable		 2feuA-4y96A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.95A 2feuB-4y96A:
undetectable		 2feuB-4y96A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 5 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.98A 2m56A-4y96A:
undetectable		 2m56A-4y96A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.97A 2qblA-4y96A:
undetectable		 2qblA-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 10 ALA A 156
ALA A 154
GLU A 110
ALA A 153
TYR A 152
 None
 1.38A 2r2vC-4y96A:
undetectable
2r2vF-4y96A:
undetectable
2r2vG-4y96A:
undetectable		 2r2vC-4y96A:
15.43
2r2vF-4y96A:
15.43
2r2vG-4y96A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.90A 2zawA-4y96A:
undetectable		 2zawA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.92A 2zaxA-4y96A:
undetectable		 2zaxA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 2zuhA-4y96A:
undetectable		 2zuhA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.93A 2zuiA-4y96A:
undetectable		 2zuiA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.93A 2zwtA-4y96A:
undetectable		 2zwtA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 2zwuA-4y96A:
undetectable		 2zwuA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 12 GLY A  28
VAL A  63
SER A  61
ALA A  26
LEU A 248
 None
 1.28A 3dh0A-4y96A:
undetectable		 3dh0A-4y96A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 5 PRO A 220
THR A  36
VAL A  35
GLY A  34
 None
 0.61A 3elzA-4y96A:
undetectable		 3elzA-4y96A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 3fwfA-4y96A:
undetectable		 3fwfA-4y96A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 3fwfB-4y96A:
undetectable		 3fwfB-4y96A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 3fwgA-4y96A:
undetectable		 3fwgA-4y96A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.93A 3fwgB-4y96A:
undetectable		 3fwgB-4y96A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 3fwiA-4y96A:
undetectable		 3fwiA-4y96A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 3fwjA-4y96A:
undetectable		 3fwjA-4y96A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 LEU A 158
GLY A 203
ALA A 207
ILE A 168
 None
CA  A 304 ( 4.2A)
None
None
 0.74A 3jusA-4y96A:
undetectable		 3jusA-4y96A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 LEU A 158
GLY A 203
ALA A 207
ILE A 168
 None
CA  A 304 ( 4.2A)
None
None
 0.74A 3jusA-4y96A:
undetectable		 3jusA-4y96A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 3l63A-4y96A:
undetectable		 3l63A-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 12 TYR A 152
PHE A 163
GLY A 203
ALA A 207
ILE A 168
 None
None
CA  A 304 ( 4.2A)
None
None
 1.13A 3ld6A-4y96A:
undetectable		 3ld6A-4y96A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 12 TYR A 152
PHE A 163
GLY A 203
ALA A 207
ILE A 168
 None
None
CA  A 304 ( 4.2A)
None
None
 1.18A 3ld6B-4y96A:
undetectable		 3ld6B-4y96A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 11 MET A 227
ILE A 250
VAL A  11
VAL A 237
HIS A 191
 None
 1.32A 3rf4A-4y96A:
1.2
3rf4C-4y96A:
undetectable		 3rf4A-4y96A:
18.92
3rf4C-4y96A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 11 HIS A 191
MET A 227
ILE A 250
VAL A  11
VAL A 237
 None
 1.34A 3rf4A-4y96A:
undetectable
3rf4B-4y96A:
undetectable		 3rf4A-4y96A:
18.92
3rf4B-4y96A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 11 HIS A 191
MET A 227
ILE A 250
VAL A  11
VAL A 237
 None
 1.33A 3rf4B-4y96A:
1.2
3rf4C-4y96A:
1.1		 3rf4B-4y96A:
18.92
3rf4C-4y96A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 3wrhA-4y96A:
undetectable		 3wrhA-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.93A 3wrhE-4y96A:
undetectable		 3wrhE-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.95A 3wrjA-4y96A:
undetectable		 3wrjA-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 3wrjE-4y96A:
undetectable		 3wrjE-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.95A 3wrlA-4y96A:
undetectable		 3wrlA-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.93A 3wrlE-4y96A:
undetectable		 3wrlE-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 3wrmA-4y96A:
undetectable		 3wrmA-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 3wrmF-4y96A:
undetectable		 3wrmF-4y96A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		3 / 3 ASP A 204
LYS A 205
ASP A 208
 None
 0.76A 4a7tA-4y96A:
undetectable		 4a7tA-4y96A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.95A 4ek1A-4y96A:
undetectable		 4ek1A-4y96A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.90A 4g3rA-4y96A:
undetectable		 4g3rA-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 4g3rB-4y96A:
undetectable		 4g3rB-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		3 / 3 HIS A  99
GLY A 216
ILE A 176
 NA  A 301 (-4.3A)
PO4  A 303 ( 4.2A)
PO4  A 303 (-4.8A)
 0.62A 4k50A-4y96A:
undetectable		 4k50A-4y96A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		3 / 3 HIS A  99
GLY A 216
ILE A 176
 NA  A 301 (-4.3A)
PO4  A 303 ( 4.2A)
PO4  A 303 (-4.8A)
 0.61A 4k50I-4y96A:
undetectable		 4k50I-4y96A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.91A 4kkyX-4y96A:
undetectable		 4kkyX-4y96A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 5 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.92A 4l49A-4y96A:
undetectable		 4l49A-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.95A 4l4aA-4y96A:
undetectable		 4l4aA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.92A 4l4bA-4y96A:
undetectable		 4l4bA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.91A 4l4cA-4y96A:
undetectable		 4l4cA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 4l4dA-4y96A:
undetectable		 4l4dA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.96A 4l4gA-4y96A:
undetectable		 4l4gA-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 12 LEU A  96
VAL A 128
GLY A 238
VAL A 167
THR A  41
 None
None
PO4  A 303 (-3.3A)
None
None
 0.91A 4m2vA-4y96A:
undetectable		 4m2vA-4y96A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 ARG A 199
ALA A 207
LEU A 198
PHE A  45
 None
 0.98A 4rkuA-4y96A:
undetectable
4rkuJ-4y96A:
undetectable		 4rkuA-4y96A:
16.90
4rkuJ-4y96A:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 VAL A 117
HIS A 118
CYH A 155
HIS A 115
 None
 1.42A 5hrqH-4y96A:
undetectable
5hrqK-4y96A:
undetectable
5hrqL-4y96A:
undetectable		 5hrqH-4y96A:
11.44
5hrqK-4y96A:
8.77
5hrqL-4y96A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 12 ILE A 250
ALA A 190
ALA A 187
VAL A 232
GLY A 132
 None
 0.97A 5igjA-4y96A:
undetectable		 5igjA-4y96A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 12 ILE A 250
ALA A 190
ALA A 187
VAL A 232
GLY A 132
 None
 0.96A 5igtA-4y96A:
undetectable		 5igtA-4y96A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		5 / 11 VAL A 218
SER A 217
THR A 178
TYR A 214
LEU A 226
 None
PO4  A 303 (-3.8A)
None
None
None
 1.34A 5jh7B-4y96A:
undetectable		 5jh7B-4y96A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 7 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.99A 5wk9A-4y96A:
undetectable		 5wk9A-4y96A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 8 PHE A 163
TYR A 202
VAL A 151
VAL A 117
 None
 0.94A 6cp4A-4y96A:
undetectable		 6cp4A-4y96A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4y96 TRIOSEPHOSPHATE
ISOMERASE
(Gemmata
obscuriglobus) 		4 / 6 GLN A 188
GLU A 189
ALA A 187
GLN A 229
 None
 1.40A 6f6jC-4y96A:
undetectable
6f6jD-4y96A:
undetectable		 6f6jC-4y96A:
23.93
6f6jD-4y96A:
23.93