SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ybg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4ybg PROTEIN MAELSTROM
(Drosophila
melanogaster) 		3 / 3 PHE A 274
PHE A 279
PHE A 280
 None
 0.60A 2od9A-4ybgA:
undetectable		 2od9A-4ybgA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4ybg PROTEIN MAELSTROM
(Drosophila
melanogaster) 		3 / 3 PHE A 274
PHE A 279
PHE A 280
 None
 0.60A 2qqgA-4ybgA:
undetectable		 2qqgA-4ybgA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4ybg PROTEIN MAELSTROM
(Drosophila
melanogaster) 		4 / 7 ILE A 239
VAL A 194
LEU A 197
SER A 198
 None
 0.71A 3r9vA-4ybgA:
undetectable
3r9vB-4ybgA:
undetectable		 3r9vA-4ybgA:
21.57
3r9vB-4ybgA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 4ybg PROTEIN MAELSTROM
(Drosophila
melanogaster) 		5 / 12 LEU A 174
ARG A 296
TYR A 299
ASN A 116
PHE A 115
 None
 1.38A 5czyA-4ybgA:
undetectable		 5czyA-4ybgA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4ybg PROTEIN MAELSTROM
(Drosophila
melanogaster) 		5 / 11 ILE A 193
ILE A 151
THR A 301
VAL A 305
VAL A 111
 None
 1.42A 5jkwA-4ybgA:
undetectable		 5jkwA-4ybgA:
19.68