SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ybh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_B_ADNB501_2 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	4ybh	ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR (Homo sapiens)	3 / 3	PRO A 289 LEU A 288 GLN A 294	None	0.63A	4pevB-4ybhA: undetectable	4pevB-4ybhA: 23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DQF_A_CZEA613_1 (SERUM ALBUMIN)	4ybh	ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR (Homo sapiens)	5 / 9	ARG A 77 ALA A 76 LEU A 79 LEU A 84 LEU A 86	ACT A 410 (-3.9A) ACT A 411 ( 4.0A) None None None	1.23A	5dqfA-4ybhA: undetectable	5dqfA-4ybhA: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLO_A_GBQA1501_1 (SUBSTANCE-P RECEPTOR,GLGA GLYCOGEN SYNTHASE,SUBSTANCE-P RECEPTOR)	4ybh	ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR (Homo sapiens)	5 / 9	ILE A 318 ILE A 320 GLU A 245 VAL A 255 ILE A 291	None	1.44A	6hloA-4ybhA: undetectable	6hloA-4ybhA: 18.58