SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ybn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 6 HIS A  63
ILE A  62
ALA A  73
VAL A  38
 HEM  A 304 ( 3.6A)
None
None
None
 1.06A 1hk1A-4ybnA:
undetectable		 1hk1A-4ybnA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A  71
GLY A  64
HIS A  63
ILE A  51
 None
HEM  A 304 (-4.0A)
HEM  A 304 ( 3.6A)
None
 0.95A 1xf1A-4ybnA:
undetectable		 1xf1A-4ybnA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A  71
GLY A  64
HIS A  63
ILE A  62
 None
HEM  A 304 (-4.0A)
HEM  A 304 ( 3.6A)
None
 0.97A 1xf1A-4ybnA:
undetectable		 1xf1A-4ybnA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 6 SER A 105
ALA A 106
SER A  83
THR A  85
 None
 1.15A 1yvpB-4ybnA:
undetectable		 1yvpB-4ybnA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 LYS A  18
ARG A  14
VAL A  12
 None
 1.09A 2r2vC-4ybnA:
undetectable
2r2vD-4ybnA:
undetectable		 2r2vC-4ybnA:
11.61
2r2vD-4ybnA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A  28
ALA A  86
ASP A  88
THR A  32
 None
 0.97A 3rozA-4ybnA:
undetectable		 3rozA-4ybnA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  52
LEU A  35
ASN A 221
ALA A 152
LEU A 124
 None
None
None
None
HEM  A 304 (-4.0A)
 1.12A 3vywA-4ybnA:
undetectable		 3vywA-4ybnA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  52
LEU A  35
ASN A 221
ALA A 152
LEU A 124
 None
None
None
None
HEM  A 304 (-4.0A)
 1.08A 3vywB-4ybnA:
undetectable		 3vywB-4ybnA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  52
LEU A  35
ASN A 221
ALA A 152
LEU A 124
 None
None
None
None
HEM  A 304 (-4.0A)
 1.07A 3vywD-4ybnA:
undetectable		 3vywD-4ybnA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ASP A  31
VAL A  84
ALA A 106
GLY A  54
PHE A  53
 None
 1.30A 4mmeB-4ybnA:
undetectable		 4mmeB-4ybnA:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 4ybn FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 VAL A  56
TYR A 123
ALA A 126
 None
ACT  A 303 (-3.7A)
ACT  A 303 ( 3.9A)
 0.00A 4ybnA-4ybnA:
33.0		 4ybnA-4ybnA:
100.00