SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ybr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 11 TYR A 199
ASP A  14
ARG A  49
HIS A  17
ILE A  16
 None
None
None
NAP  A 301 (-4.0A)
None
 1.39A 1tcoC-4ybrA:
undetectable		 1tcoC-4ybrA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 11 TYR A 199
ASP A  14
ARG A  49
HIS A  20
ILE A  16
 None
None
None
NAP  A 301 (-3.8A)
None
 1.38A 1tcoC-4ybrA:
undetectable		 1tcoC-4ybrA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 MET A   9
GLY A 131
ALA A 108
ASP A 109
TYR A 137
 NAP  A 301 (-3.5A)
None
None
None
None
 1.46A 2avdA-4ybrA:
undetectable		 2avdA-4ybrA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 7 VAL A  37
SER A  74
LEU A 102
THR A  89
 None
 1.15A 2f78A-4ybrA:
undetectable		 2f78A-4ybrA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 7 VAL A  37
SER A  74
LEU A 102
THR A  89
 None
 1.18A 2f78B-4ybrA:
undetectable		 2f78B-4ybrA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A  71
PHE A  38
PHE A  13
HIS A  20
 None
None
NAP  A 301 ( 4.9A)
NAP  A 301 (-3.8A)
 1.07A 2lh6A-4ybrA:
undetectable		 2lh6A-4ybrA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A  70
THR A  61
THR A 105
 None
 0.78A 3k2hB-4ybrA:
1.8		 3k2hB-4ybrA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.02A 4jksA-4ybrA:
2.2		 4jksA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.02A 4jksB-4ybrA:
2.3		 4jksB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4jkuA-4ybrA:
undetectable		 4jkuA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.02A 4k8cA-4ybrA:
2.5		 4k8cA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4k8cB-4ybrA:
2.2		 4k8cB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.01A 4k8kA-4ybrA:
2.3		 4k8kA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.01A 4k8kB-4ybrA:
2.2		 4k8kB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4kahA-4ybrA:
2.6		 4kahA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4kahB-4ybrA:
2.3		 4kahB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4kalA-4ybrA:
2.2		 4kalA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.02A 4kalB-4ybrA:
undetectable		 4kalB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4kanA-4ybrA:
2.6		 4kanA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.03A 4kanB-4ybrA:
2.3		 4kanB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.04A 4kbeA-4ybrA:
2.5		 4kbeA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.02A 4kbeB-4ybrA:
2.5		 4kbeB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.02A 4lbgA-4ybrA:
2.3		 4lbgA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.01A 4lbgB-4ybrA:
2.2		 4lbgB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.01A 4lcaA-4ybrA:
2.2		 4lcaA-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  10
GLY A  11
ILE A 114
THR A  86
ASP A  77
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.9A)
NAP  A 301 (-4.0A)
None
 1.04A 4lcaB-4ybrA:
undetectable		 4lcaB-4ybrA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 TYR A 137
GLY A 131
LEU A 156
SER A 133
ALA A 110
 None
None
None
None
NAP  A 301 (-3.6A)
 0.96A 4qtuB-4ybrA:
undetectable		 4qtuB-4ybrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 TYR A 137
GLY A 131
SER A 133
ILE A 114
ALA A 110
 None
None
None
NAP  A 301 (-3.9A)
NAP  A 301 (-3.6A)
 0.92A 4qtuB-4ybrA:
undetectable		 4qtuB-4ybrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 7 GLU A 101
TYR A 103
ASP A 154
ALA A 155
 None
 0.82A 4zz8A-4ybrA:
undetectable		 4zz8A-4ybrA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 8 GLY A  10
ILE A 161
SER A 133
GLY A 107
 NAP  A 301 (-3.1A)
None
None
NAP  A 301 (-3.1A)
 0.76A 5alcL-4ybrA:
undetectable		 5alcL-4ybrA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  11
HIS A  17
THR A 106
GLY A 107
GLY A   7
 NAP  A 301 (-3.4A)
NAP  A 301 (-4.0A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.1A)
None
 1.07A 5d4uA-4ybrA:
undetectable		 5d4uA-4ybrA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  11
HIS A  17
THR A 106
GLY A 107
GLY A   7
 NAP  A 301 (-3.4A)
NAP  A 301 (-4.0A)
NAP  A 301 (-3.4A)
NAP  A 301 (-3.1A)
None
 1.07A 5d4uB-4ybrA:
undetectable		 5d4uB-4ybrA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 SER A 133
VAL A 132
GLY A 107
ALA A 108
 None
NAP  A 301 (-4.8A)
NAP  A 301 (-3.1A)
None
 0.85A 5k50A-4ybrA:
3.7		 5k50A-4ybrA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 4 GLY A   7
LEU A   6
VAL A  37
GLU A  35
 None
 1.24A 5yw0A-4ybrA:
undetectable		 5yw0A-4ybrA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  78
GLY A  42
THR A  84
VAL A   8
VAL A  37
 None
None
NAP  A 301 (-3.9A)
None
None
 1.03A 6emuC-4ybrA:
2.3		 6emuC-4ybrA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 5 GLY A  11
THR A  12
HIS A  20
SER A 167
SER A 168
 NAP  A 301 (-3.4A)
NAP  A 301 (-3.7A)
NAP  A 301 (-3.8A)
None
NAP  A 301 (-2.4A)
 0.93A 6jmjA-4ybrA:
15.1		 6jmjA-4ybrA:
27.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		6 / 7 GLY A  11
THR A  12
PHE A  13
HIS A  20
SER A 167
SER A 168
 NAP  A 301 (-3.4A)
NAP  A 301 (-3.7A)
NAP  A 301 ( 4.9A)
NAP  A 301 (-3.8A)
None
NAP  A 301 (-2.4A)
 0.90A 6jnhA-4ybrA:
15.2		 6jnhA-4ybrA:
27.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 6 GLY A  11
THR A  12
HIS A  20
SER A 167
SER A 168
 NAP  A 301 (-3.4A)
NAP  A 301 (-3.7A)
NAP  A 301 (-3.8A)
None
NAP  A 301 (-2.4A)
 0.94A 6jogA-4ybrA:
15.0		 6jogA-4ybrA:
27.49