SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQP_A_803A311_1 (ANTIGEN CD11A (P180))	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 10	LEU A 78 VAL A 69 ILE A 52 GLU A 40 LEU A 37	None	1.19A	1cqpA-4yc6A: undetectable 1cqpB-4yc6A: undetectable	1cqpA-4yc6A: 24.56 1cqpB-4yc6A: 24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DF7_A_MTXA501_1 (DIHYDROFOLATE REDUCTASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	ALA A 281 ILE A 187 LEU A 129 LEU A 144 ILE A 112	None	0.94A	1df7A-4yc6A: undetectable	1df7A-4yc6A: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OPJ_A_STIA3_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	VAL A 18 ALA A 31 VAL A 64 PHE A 82 LEU A 135 ALA A 145	None	0.70A	1opjA-4yc6A: 21.9	1opjA-4yc6A: 27.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJF_B_ADNB2002_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	4 / 6	ARG A 180 GLU A 173 PRO A 272 ALA A 273	None	1.33A	2ejfB-4yc6A: undetectable	2ejfB-4yc6A: 23.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 VAL A 64 PHE A 80 ASP A 86 ASN A 133 LEU A 135 ALA A 145	None	0.85A	2eufB-4yc6A: 29.8	2eufB-4yc6A: 46.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BBT_B_FMMB91_1 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	VAL A 18 ALA A 31 LEU A 66 LEU A 135 ASP A 146 PHE A 147	None	0.60A	3bbtB-4yc6A: 24.6	3bbtB-4yc6A: 24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BBT_D_FMMD91_1 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 ALA A 31 LEU A 78 LEU A 135 ASP A 146 PHE A 147 LEU A 149	None	0.73A	3bbtD-4yc6A: 24.6	3bbtD-4yc6A: 24.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MIY_A_B49A1_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 11	ILE A 10 ALA A 31 LYS A 33 VAL A 64 PHE A 80 LEU A 135 ASP A 146	None	0.74A	3miyA-4yc6A: 23.5	3miyA-4yc6A: 30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MIY_A_B49A1_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 11	ILE A 10 ALA A 31 VAL A 64 PHE A 80 PHE A 82 LEU A 135 ASP A 146	None	0.66A	3miyA-4yc6A: 23.5	3miyA-4yc6A: 30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MIY_B_B49B2_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 9	ILE A 10 ALA A 31 LYS A 33 PHE A 80 LEU A 135	None	0.72A	3miyB-4yc6A: 23.4	3miyB-4yc6A: 30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MIY_B_B49B2_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 9	ILE A 10 ALA A 31 PHE A 80 PHE A 82 LEU A 135	None	0.54A	3miyB-4yc6A: 23.4	3miyB-4yc6A: 30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TI1_A_B49A299_1 (CYCLIN-DEPENDENT KINASE 2)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 9	ALA A 31 VAL A 64 PHE A 80 PHE A 82 ASP A 86 LEU A 135	None	0.53A	3ti1A-4yc6A: 36.2	3ti1A-4yc6A: 65.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TI1_A_B49A299_1 (CYCLIN-DEPENDENT KINASE 2)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 9	ILE A 10 ALA A 31 VAL A 64 PHE A 80 PHE A 82	None	0.61A	3ti1A-4yc6A: 36.2	3ti1A-4yc6A: 65.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TI1_A_B49A299_1 (CYCLIN-DEPENDENT KINASE 2)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 9	VAL A 64 PHE A 80 ASP A 86 LEU A 135 ASP A 146	None	0.83A	3ti1A-4yc6A: 36.2	3ti1A-4yc6A: 65.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AN2_A_EUIA1382_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	LEU A 66 ASP A 128 LYS A 130 ASN A 133 ASP A 146 GLY A 148	None	1.17A	4an2A-4yc6A: 25.0	4an2A-4yc6A: 30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AN2_A_EUIA1382_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	LYS A 33 ASP A 128 LYS A 130 ASN A 133 ASP A 146 GLY A 148	None	0.98A	4an2A-4yc6A: 25.0	4an2A-4yc6A: 30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AN2_A_EUIA1382_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	LYS A 33 LEU A 55 ASP A 128 LYS A 130 ASN A 133 ASP A 146	None	1.09A	4an2A-4yc6A: 25.0	4an2A-4yc6A: 30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	4 / 4	LEU A 87 PRO A 131 LEU A 134 ILE A 142	None	0.95A	4f4dB-4yc6A: undetectable	4f4dB-4yc6A: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	4 / 5	LEU A 87 PRO A 131 LEU A 134 ILE A 142	None	0.91A	4klrA-4yc6A: undetectable	4klrA-4yc6A: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 10	ILE A 10 ALA A 31 VAL A 64 PHE A 82 LEU A 83 LEU A 135 ASP A 146	None	0.79A	4ks8A-4yc6A: 24.1	4ks8A-4yc6A: 27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LMN_A_EUIA503_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	LEU A 66 ASN A 133 ASP A 146 PHE A 147 GLY A 148	None	0.97A	4lmnA-4yc6A: 16.9	4lmnA-4yc6A: 29.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LMN_A_EUIA503_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	LYS A 33 ASN A 133 ASP A 146 PHE A 147 GLY A 148	None	0.95A	4lmnA-4yc6A: 16.9	4lmnA-4yc6A: 29.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_A_TMQA202_1 (DIHYDROFOLATE REDUCTASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	ALA A 281 ILE A 187 LEU A 129 LEU A 144 ILE A 112	None	0.95A	4m2xA-4yc6A: undetectable	4m2xA-4yc6A: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_C_TMQC202_1 (DIHYDROFOLATE REDUCTASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	ALA A 281 ILE A 187 LEU A 129 LEU A 144 ILE A 112	None	0.91A	4m2xC-4yc6A: undetectable	4m2xC-4yc6A: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_E_TMQE202_1 (DIHYDROFOLATE REDUCTASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	ALA A 281 ILE A 187 LEU A 129 LEU A 144 ILE A 112	None	0.89A	4m2xE-4yc6A: undetectable	4m2xE-4yc6A: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O0U_A_ADNA501_1 (AURORA KINASE A)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	4 / 6	VAL A 18 ALA A 31 LYS A 33 LEU A 135	None	0.75A	4o0uA-4yc6A: 8.2	4o0uA-4yc6A: 29.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OGR_E_ADNE401_1 (CYCLIN-DEPENDENT KINASE 9)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 7	ALA A 31 ASP A 86 ASN A 133 LEU A 135 ASP A 146	None	0.80A	4ogrE-4yc6A: 30.0	4ogrE-4yc6A: 40.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OGR_I_ADNI401_1 (CYCLIN-DEPENDENT KINASE 9)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 9	GLY A 13 VAL A 18 ALA A 31 ASP A 86 ASN A 133 LEU A 135	None	0.86A	4ogrI-4yc6A: 30.4	4ogrI-4yc6A: 40.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OGR_I_ADNI401_1 (CYCLIN-DEPENDENT KINASE 9)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 9	VAL A 18 ALA A 31 ASP A 86 ASN A 133 LEU A 135 ASP A 146	None	0.89A	4ogrI-4yc6A: 30.4	4ogrI-4yc6A: 40.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMZ_A_B49A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	ILE A 10 GLY A 11 VAL A 18 ALA A 31 LEU A 83 LEU A 135	None	0.68A	4qmzA-4yc6A: 24.5	4qmzA-4yc6A: 29.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J7W_D_MTXD402_1 (THYMIDYLATE SYNTHASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	LEU A 149 GLY A 148 PHE A 147 ILE A 52 ALA A 48	None	1.06A	5j7wD-4yc6A: undetectable	5j7wD-4yc6A: 23.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	GLY A 13 ALA A 31 VAL A 64 ASP A 86 LEU A 135 ALA A 145 ASP A 146	None	1.34A	5l2iA-4yc6A: 14.6	5l2iA-4yc6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 ALA A 31 VAL A 64 PHE A 80 ASP A 86 LEU A 135 ALA A 145	None	0.68A	5l2iA-4yc6A: 14.6	5l2iA-4yc6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	GLY A 11 VAL A 18 ALA A 31 VAL A 64 PHE A 80 LEU A 135 ALA A 145	None	0.88A	5l2tA-4yc6A: 14.8	5l2tA-4yc6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 ALA A 31 VAL A 64 ASP A 86 LEU A 135 ALA A 145 ASP A 146	None	0.98A	5l2tA-4yc6A: 14.8	5l2tA-4yc6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 ALA A 31 VAL A 64 PHE A 80 ASP A 86 LEU A 135 ALA A 145	None	0.69A	5l2tA-4yc6A: 14.8	5l2tA-4yc6A: 45.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5P9I_A_1E8A701_1 (TYROSINE-PROTEIN KINASE BTK)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	GLY A 13 VAL A 18 ALA A 31 LYS A 33 LEU A 135 PHE A 147	None	0.80A	5p9iA-4yc6A: 26.1	5p9iA-4yc6A: 25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	GLY A 11 VAL A 18 ALA A 31 PHE A 80 ALA A 145	None	0.50A	5xv7A-4yc6A: 26.0	5xv7A-4yc6A: 12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YU9_A_1E8A1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	GLY A 11 VAL A 18 ALA A 31 LYS A 33 LEU A 78 LEU A 135 ASP A 146	None	0.68A	5yu9A-4yc6A: 23.5	5yu9A-4yc6A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YU9_B_1E8B1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	GLY A 11 VAL A 18 ALA A 31 LYS A 33 LEU A 78 LEU A 135 ASP A 146	None	0.68A	5yu9B-4yc6A: 23.8	5yu9B-4yc6A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YU9_C_1E8C1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	VAL A 18 ALA A 31 LYS A 33 LEU A 78 ASP A 146	None	0.65A	5yu9C-4yc6A: 23.7	5yu9C-4yc6A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YU9_D_1E8D1101_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	6 / 12	VAL A 18 ALA A 31 LYS A 33 LEU A 135 ASP A 146 LEU A 149	None	0.72A	5yu9D-4yc6A: 24.2	5yu9D-4yc6A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A4I_B_TRPB403_0 (TRYPTOPHAN 2,3-DIOXYGENASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	4 / 7	ARG A 170 TRP A 168 PRO A 131 PRO A 202	None	1.39A	6a4iB-4yc6A: undetectable	6a4iB-4yc6A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Z_D_9CRD501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	ILE A 112 ILE A 136 LEU A 144 ALA A 145 LEU A 197	None	1.11A	6a5zD-4yc6A: undetectable	6a5zD-4yc6A: 15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC605_0 (ALPHA-AMYLASE)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	4 / 8	GLY A 115 ILE A 63 ASP A 186 HIS A 126	None	1.02A	6ag0C-4yc6A: undetectable	6ag0C-4yc6A: 13.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CQP_A_803A311_1","ANTIGEN CD11A (P180);ANTIGEN CD11A (P180)","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"LEU A  78;VAL A  69;ILE A  52;GLU A  40;LEU A  37","None","1.19A","1cqpA-4yc6A:undetectable;1cqpB-4yc6A:undetectable","1cqpA-4yc6A:24.56;1cqpB-4yc6A:24.56"],["1DF7_A_MTXA501_1","DIHYDROFOLATE REDUCTASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ALA A 281;ILE A 187;LEU A 129;LEU A 144;ILE A 112","None","0.94A","1df7A-4yc6A:undetectable","1df7A-4yc6A:22.53"],["1OPJ_A_STIA3_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"VAL A  18;ALA A  31;VAL A  64;PHE A  82;LEU A 135;ALA A 145","None","0.70A","1opjA-4yc6A:21.9","1opjA-4yc6A:27.56"],["2EJF_B_ADNB2002_1","235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",4,"ARG A 180;GLU A 173;PRO A 272;ALA A 273","None","1.33A","2ejfB-4yc6A:undetectable","2ejfB-4yc6A:23.81"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"VAL A  18;VAL A  64;PHE A  80;ASP A  86;ASN A 133;LEU A 135;ALA A 145","None","0.85A","2eufB-4yc6A:29.8","2eufB-4yc6A:46.11"],["3BBT_B_FMMB91_1","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"VAL A  18;ALA A  31;LEU A  66;LEU A 135;ASP A 146;PHE A 147","None","0.60A","3bbtB-4yc6A:24.6","3bbtB-4yc6A:24.70"],["3BBT_D_FMMD91_1","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"VAL A  18;ALA A  31;LEU A  78;LEU A 135;ASP A 146;PHE A 147;LEU A 149","None","0.73A","3bbtD-4yc6A:24.6","3bbtD-4yc6A:24.70"],["3MIY_A_B49A1_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"ILE A  10;ALA A  31;LYS A  33;VAL A  64;PHE A  80;LEU A 135;ASP A 146","None","0.74A","3miyA-4yc6A:23.5","3miyA-4yc6A:30.69"],["3MIY_A_B49A1_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"ILE A  10;ALA A  31;VAL A  64;PHE A  80;PHE A  82;LEU A 135;ASP A 146","None","0.66A","3miyA-4yc6A:23.5","3miyA-4yc6A:30.69"],["3MIY_B_B49B2_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ILE A  10;ALA A  31;LYS A  33;PHE A  80;LEU A 135","None","0.72A","3miyB-4yc6A:23.4","3miyB-4yc6A:30.69"],["3MIY_B_B49B2_1","TYROSINE-PROTEIN KINASE ITK\/TSK","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ILE A  10;ALA A  31;PHE A  80;PHE A  82;LEU A 135","None","0.54A","3miyB-4yc6A:23.4","3miyB-4yc6A:30.69"],["3TI1_A_B49A299_1","CYCLIN-DEPENDENT KINASE 2","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"ALA A  31;VAL A  64;PHE A  80;PHE A  82;ASP A  86;LEU A 135","None","0.53A","3ti1A-4yc6A:36.2","3ti1A-4yc6A:65.77"],["3TI1_A_B49A299_1","CYCLIN-DEPENDENT KINASE 2","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ILE A  10;ALA A  31;VAL A  64;PHE A  80;PHE A  82","None","0.61A","3ti1A-4yc6A:36.2","3ti1A-4yc6A:65.77"],["3TI1_A_B49A299_1","CYCLIN-DEPENDENT KINASE 2","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"VAL A  64;PHE A  80;ASP A  86;LEU A 135;ASP A 146","None","0.83A","3ti1A-4yc6A:36.2","3ti1A-4yc6A:65.77"],["4AN2_A_EUIA1382_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"LEU A  66;ASP A 128;LYS A 130;ASN A 133;ASP A 146;GLY A 148","None","1.17A","4an2A-4yc6A:25.0","4an2A-4yc6A:30.62"],["4AN2_A_EUIA1382_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"LYS A  33;ASP A 128;LYS A 130;ASN A 133;ASP A 146;GLY A 148","None","0.98A","4an2A-4yc6A:25.0","4an2A-4yc6A:30.62"],["4AN2_A_EUIA1382_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"LYS A  33;LEU A  55;ASP A 128;LYS A 130;ASN A 133;ASP A 146","None","1.09A","4an2A-4yc6A:25.0","4an2A-4yc6A:30.62"],["4F4D_B_CHDB504_0","FERROCHELATASE, MITOCHONDRIAL","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",4,"LEU A  87;PRO A 131;LEU A 134;ILE A 142","None","0.95A","4f4dB-4yc6A:undetectable","4f4dB-4yc6A:21.55"],["4KLR_A_CHDA505_0","FERROCHELATASE, MITOCHONDRIAL","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",4,"LEU A  87;PRO A 131;LEU A 134;ILE A 142","None","0.91A","4klrA-4yc6A:undetectable","4klrA-4yc6A:21.93"],["4KS8_A_B49A701_1","SERINE\/THREONINE-PROTEIN KINASE PAK 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"ILE A  10;ALA A  31;VAL A  64;PHE A  82;LEU A  83;LEU A 135;ASP A 146","None","0.79A","4ks8A-4yc6A:24.1","4ks8A-4yc6A:27.51"],["4LMN_A_EUIA503_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"LEU A  66;ASN A 133;ASP A 146;PHE A 147;GLY A 148","None","0.97A","4lmnA-4yc6A:16.9","4lmnA-4yc6A:29.46"],["4LMN_A_EUIA503_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"LYS A  33;ASN A 133;ASP A 146;PHE A 147;GLY A 148","None","0.95A","4lmnA-4yc6A:16.9","4lmnA-4yc6A:29.46"],["4M2X_A_TMQA202_1","DIHYDROFOLATE REDUCTASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ALA A 281;ILE A 187;LEU A 129;LEU A 144;ILE A 112","None","0.95A","4m2xA-4yc6A:undetectable","4m2xA-4yc6A:21.71"],["4M2X_C_TMQC202_1","DIHYDROFOLATE REDUCTASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ALA A 281;ILE A 187;LEU A 129;LEU A 144;ILE A 112","None","0.91A","4m2xC-4yc6A:undetectable","4m2xC-4yc6A:21.71"],["4M2X_E_TMQE202_1","DIHYDROFOLATE REDUCTASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ALA A 281;ILE A 187;LEU A 129;LEU A 144;ILE A 112","None","0.89A","4m2xE-4yc6A:undetectable","4m2xE-4yc6A:21.71"],["4O0U_A_ADNA501_1","AURORA KINASE A","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",4,"VAL A  18;ALA A  31;LYS A  33;LEU A 135","None","0.75A","4o0uA-4yc6A:8.2","4o0uA-4yc6A:29.02"],["4OGR_E_ADNE401_1","CYCLIN-DEPENDENT KINASE 9","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ALA A  31;ASP A  86;ASN A 133;LEU A 135;ASP A 146","None","0.80A","4ogrE-4yc6A:30.0","4ogrE-4yc6A:40.70"],["4OGR_I_ADNI401_1","CYCLIN-DEPENDENT KINASE 9","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"GLY A  13;VAL A  18;ALA A  31;ASP A  86;ASN A 133;LEU A 135","None","0.86A","4ogrI-4yc6A:30.4","4ogrI-4yc6A:40.70"],["4OGR_I_ADNI401_1","CYCLIN-DEPENDENT KINASE 9","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"VAL A  18;ALA A  31;ASP A  86;ASN A 133;LEU A 135;ASP A 146","None","0.89A","4ogrI-4yc6A:30.4","4ogrI-4yc6A:40.70"],["4QMZ_A_B49A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"ILE A  10;GLY A  11;VAL A  18;ALA A  31;LEU A  83;LEU A 135","None","0.68A","4qmzA-4yc6A:24.5","4qmzA-4yc6A:29.97"],["5J7W_D_MTXD402_1","THYMIDYLATE SYNTHASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"LEU A 149;GLY A 148;PHE A 147;ILE A  52;ALA A  48","None","1.06A","5j7wD-4yc6A:undetectable","5j7wD-4yc6A:23.15"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"GLY A  13;ALA A  31;VAL A  64;ASP A  86;LEU A 135;ALA A 145;ASP A 146","None","1.34A","5l2iA-4yc6A:14.6","5l2iA-4yc6A:45.60"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"VAL A  18;ALA A  31;VAL A  64;PHE A  80;ASP A  86;LEU A 135;ALA A 145","None","0.68A","5l2iA-4yc6A:14.6","5l2iA-4yc6A:45.60"],["5L2T_A_6ZZA900_1","CYCLIN-DEPENDENT KINASE 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"GLY A  11;VAL A  18;ALA A  31;VAL A  64;PHE A  80;LEU A 135;ALA A 145","None","0.88A","5l2tA-4yc6A:14.8","5l2tA-4yc6A:45.60"],["5L2T_A_6ZZA900_1","CYCLIN-DEPENDENT KINASE 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"VAL A  18;ALA A  31;VAL A  64;ASP A  86;LEU A 135;ALA A 145;ASP A 146","None","0.98A","5l2tA-4yc6A:14.8","5l2tA-4yc6A:45.60"],["5L2T_A_6ZZA900_1","CYCLIN-DEPENDENT KINASE 6","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"VAL A  18;ALA A  31;VAL A  64;PHE A  80;ASP A  86;LEU A 135;ALA A 145","None","0.69A","5l2tA-4yc6A:14.8","5l2tA-4yc6A:45.60"],["5P9I_A_1E8A701_1","TYROSINE-PROTEIN KINASE BTK","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"GLY A  13;VAL A  18;ALA A  31;LYS A  33;LEU A 135;PHE A 147","None","0.80A","5p9iA-4yc6A:26.1","5p9iA-4yc6A:25.99"],["5XV7_A_EMHA705_1","SERINE-ARGININE (SR) PROTEIN KINASE 1","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"GLY A  11;VAL A  18;ALA A  31;PHE A  80;ALA A 145","None","0.50A","5xv7A-4yc6A:26.0","5xv7A-4yc6A:12.97"],["5YU9_A_1E8A1101_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"GLY A  11;VAL A  18;ALA A  31;LYS A  33;LEU A  78;LEU A 135;ASP A 146","None","0.68A","5yu9A-4yc6A:23.5","5yu9A-4yc6A:16.67"],["5YU9_B_1E8B1101_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",7,"GLY A  11;VAL A  18;ALA A  31;LYS A  33;LEU A  78;LEU A 135;ASP A 146","None","0.68A","5yu9B-4yc6A:23.8","5yu9B-4yc6A:16.67"],["5YU9_C_1E8C1101_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"VAL A  18;ALA A  31;LYS A  33;LEU A  78;ASP A 146","None","0.65A","5yu9C-4yc6A:23.7","5yu9C-4yc6A:16.67"],["5YU9_D_1E8D1101_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",6,"VAL A  18;ALA A  31;LYS A  33;LEU A 135;ASP A 146;LEU A 149","None","0.72A","5yu9D-4yc6A:24.2","5yu9D-4yc6A:16.67"],["6A4I_B_TRPB403_0","TRYPTOPHAN 2,3-DIOXYGENASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",4,"ARG A 170;TRP A 168;PRO A 131;PRO A 202","None","1.39A","6a4iB-4yc6A:undetectable","6a4iB-4yc6A:22.28"],["6A5Z_D_9CRD501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",5,"ILE A 112;ILE A 136;LEU A 144;ALA A 145;LEU A 197","None","1.11A","6a5zD-4yc6A:undetectable","6a5zD-4yc6A:15.00"],["6AG0_C_ACRC605_0","ALPHA-AMYLASE","4yc6","CYCLIN-DEPENDENT KINASE 1","Homo sapiens",4,"GLY A 115;ILE A  63;ASP A 186;HIS A 126","None","1.02A","6ag0C-4yc6A:undetectable","6ag0C-4yc6A:13.76"]]