SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ydh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 ILE A  84
LEU A  87
VAL A  91
ALA A 214
 None
 0.81A 1mz9A-4ydhA:
undetectable		 1mz9A-4ydhA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 9 TYR A 153
ASP A 226
LEU A  87
ILE A 220
PHE A 156
 None
 1.47A 1q6iA-4ydhA:
undetectable		 1q6iA-4ydhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 10 TYR A 153
ASP A 226
LEU A  87
ILE A 220
PHE A 156
 None
 1.46A 1q6iB-4ydhA:
undetectable		 1q6iB-4ydhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 SER A 222
SER A 218
LEU A 154
PHE A 156
 None
 1.04A 1r5lA-4ydhA:
undetectable		 1r5lA-4ydhA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 11 LEU A 271
LEU A 275
VAL A 279
ILE A 231
LEU A 154
 None
 1.26A 2q6hA-4ydhA:
undetectable		 2q6hA-4ydhA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 10 TYR A 153
ASP A 226
LEU A  87
ILE A 220
PHE A 156
 None
 1.36A 3kz7A-4ydhA:
undetectable		 3kz7A-4ydhA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 12 ILE A 288
ALA A 291
ALA A 292
VAL A 282
LEU A 276
 None
 1.23A 3uvvB-4ydhA:
undetectable		 3uvvB-4ydhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 6 THR A 351
GLY A 354
ARG A 305
LEU A 359
 None
 1.26A 4acaC-4ydhA:
undetectable		 4acaC-4ydhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 ASP A 294
ARG A 305
ASP A 287
 None
 0.82A 4fzvA-4ydhA:
undetectable		 4fzvA-4ydhA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 12 ASP A 287
HIS A 286
PHE A 329
ALA A 258
PHE A 293
 None
 1.37A 4wh5A-4ydhA:
undetectable		 4wh5A-4ydhA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 9 LEU A 261
GLU A 298
PHE A 296
VAL A 299
GLU A 311
 None
 1.21A 5igzA-4ydhA:
undetectable		 5igzA-4ydhA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 ASP A 287
PHE A 342
ARG A 305
 None
 1.06A 5yw0A-4ydhA:
undetectable		 5yw0A-4ydhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 ASP A 294
ARG A 305
ASP A 287
 None
 0.88A 5zvgA-4ydhA:
undetectable		 5zvgA-4ydhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4ydh FORMIN-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 ASP A 294
ARG A 305
ASP A 287
 None
 0.86A 5zvgB-4ydhA:
undetectable		 5zvgB-4ydhA:
21.09