SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ydq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 10 TYR A 435
VAL A 441
ARG A 514
VAL A 535
ILE A 400
 None
None
ANP  A 801 (-3.2A)
None
None
 1.35A 13gsA-4ydqA:
undetectable		 13gsA-4ydqA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.04A 1jhoA-4ydqA:
undetectable		 1jhoA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.05A 1jhrA-4ydqA:
undetectable		 1jhrA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.06A 1jhyA-4ydqA:
undetectable		 1jhyA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.06A 1l4nA-4ydqA:
undetectable		 1l4nA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.04A 1l5kA-4ydqA:
undetectable		 1l5kA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.04A 1l5lA-4ydqA:
undetectable		 1l5lA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.04A 1l5mA-4ydqA:
undetectable		 1l5mA-4ydqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 7 ASP A 576
ASP A 577
LYS A 586
HIS A 589
 None
 1.45A 1t03A-4ydqA:
undetectable		 1t03A-4ydqA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 SER A 282
ILE A 281
VAL A 389
THR A 513
 None
 1.08A 1u70A-4ydqA:
undetectable		 1u70A-4ydqA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 ARG A 403
GLN A 395
PRO A 396
 None
 1.00A 2qhfA-4ydqA:
undetectable		 2qhfA-4ydqA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W13_A_ACTA1208_0
(ZINC
METALLOPROTEINASE
BAP1)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
ARG A 357
GLU A 409
ASN A 386
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 4.9A)
None
 1.23A 2w13A-4ydqA:
undetectable		 2w13A-4ydqA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 GLY A 517
ILE A 518
PRO A 532
VAL A 535
ILE A 294
 None
 1.11A 3ekyB-4ydqA:
undetectable		 3ekyB-4ydqA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 GLU A 563
VAL A 574
CYH A 573
 None
 0.92A 3fbxA-4ydqA:
undetectable		 3fbxA-4ydqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 8 GLU A 326
LYS A 324
ASN A 323
ILE A 354
 None
 1.34A 3kp6A-4ydqA:
0.6
3kp6B-4ydqA:
0.9		 3kp6A-4ydqA:
15.51
3kp6B-4ydqA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 5 VAL A 298
ILE A 276
TYR A 293
ILE A 270
 None
 0.85A 4c8bA-4ydqA:
undetectable		 4c8bA-4ydqA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 7 TYR A 435
VAL A 441
LEU A 439
ASN A 470
 None
 1.02A 4e1gB-4ydqA:
undetectable		 4e1gB-4ydqA:
20.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 12 GLU A 392
GLU A 409
HIS A 411
THR A 478
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.91A 4hvcA-4ydqA:
50.6		 4hvcA-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.36A 4hvcA-4ydqA:
50.6		 4hvcA-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
TRP A 407
PHE A 454
THR A 478
SER A 508
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.71A 4hvcA-4ydqA:
50.6		 4hvcA-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_A_HFGA1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
ARG A 390
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.0A)
 0.24A 4hvcA-4ydqA:
50.6		 4hvcA-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 12 GLU A 392
GLU A 409
HIS A 411
THR A 478
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.95A 4hvcB-4ydqA:
50.8		 4hvcB-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.38A 4hvcB-4ydqA:
50.8		 4hvcB-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
TRP A 407
PHE A 454
THR A 478
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.68A 4hvcB-4ydqA:
50.8		 4hvcB-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 5 THR A 359
GLU A 361
ARG A 390
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.0A)
 0.22A 4hvcB-4ydqA:
50.8		 4hvcB-4ydqA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 8 ARG A 390
PHE A 405
GLN A 475
THR A 478
THR A 512
ARG A 514
 ANP  A 801 ( 2.5A)
ANP  A 801 (-3.9A)
ANP  A 801 (-4.4A)
HFG  A 802 ( 4.0A)
ANP  A 801 (-3.1A)
ANP  A 801 (-3.2A)
 0.45A 4k87A-4ydqA:
49.4		 4k87A-4ydqA:
49.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 GLU A 392
PRO A 358
THR A 359
GLU A 361
ARG A 390
GLU A 409
PHE A 454
HIS A 480
SER A 508
 ANP  A 801 (-3.6A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 (-4.0A)
HFG  A 802 ( 3.8A)
 1.41A 4k88A-4ydqA:
49.1		 4k88A-4ydqA:
49.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
GLU A 361
ARG A 390
GLU A 409
PHE A 454
HIS A 480
SER A 508
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 (-4.0A)
HFG  A 802 ( 3.8A)
 0.66A 4k88A-4ydqA:
49.1		 4k88A-4ydqA:
49.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
GLU A 361
ARG A 390
TRP A 407
PHE A 454
HIS A 480
SER A 508
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 (-4.0A)
HFG  A 802 ( 3.8A)
 0.80A 4k88A-4ydqA:
49.1		 4k88A-4ydqA:
49.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 THR A 359
GLY A 410
SER A 508
GLU A 361
GLY A 510
 HFG  A 802 (-3.2A)
None
HFG  A 802 ( 3.8A)
HFG  A 802 (-2.9A)
HFG  A 802 (-3.7A)
 1.09A 4kqiA-4ydqA:
undetectable		 4kqiA-4ydqA:
19.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
GLU A 409
HIS A 411
THR A 478
SER A 508
TRP A 509
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
None
HFG  A 802 (-3.7A)
 1.14A 4olfA-4ydqA:
54.2		 4olfA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
TRP A 509
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
None
HFG  A 802 (-3.7A)
 0.30A 4olfA-4ydqA:
54.2		 4olfA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
TRP A 407
PHE A 454
THR A 478
SER A 508
TRP A 509
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
None
HFG  A 802 (-3.7A)
 0.61A 4olfA-4ydqA:
54.2		 4olfA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 12 PHE A 335
HIS A 411
PHE A 454
THR A 460
SER A 508
 HFG  A 802 (-3.4A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
None
HFG  A 802 ( 3.8A)
 1.40A 4olfA-4ydqA:
54.2		 4olfA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLF_A_HFGA802_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
ARG A 390
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.0A)
 0.27A 4olfA-4ydqA:
54.2		 4olfA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 12 GLU A 392
THR A 359
ARG A 390
HIS A 411
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.34A 4q15A-4ydqA:
52.1		 4q15A-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
TRP A 407
HIS A 411
PHE A 454
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.56A 4q15A-4ydqA:
52.1		 4q15A-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 GLU A 361
THR A 478
HIS A 480
 HFG  A 802 (-2.9A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.30A 4q15A-4ydqA:
52.1		 4q15A-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
THR A 359
ARG A 390
GLU A 409
PHE A 454
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.32A 4q15B-4ydqA:
52.8		 4q15B-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
TRP A 407
GLU A 409
PHE A 454
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.53A 4q15B-4ydqA:
52.8		 4q15B-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 GLU A 361
THR A 478
HIS A 480
 HFG  A 802 (-2.9A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.34A 4q15B-4ydqA:
52.8		 4q15B-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
ARG A 390
GLU A 409
HIS A 411
PHE A 454
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.29A 4ydqA-4ydqA:
59.3		 4ydqA-4ydqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
TRP A 407
GLU A 409
HIS A 411
PHE A 454
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.00A 4ydqA-4ydqA:
59.3		 4ydqA-4ydqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_A_HFGA802_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
THR A 478
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.31A 4ydqA-4ydqA:
59.3		 4ydqA-4ydqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
THR A 359
ARG A 390
GLU A 409
HIS A 411
PHE A 454
SER A 508
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
 1.34A 4ydqB-4ydqA:
54.6		 4ydqB-4ydqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
TRP A 407
GLU A 409
HIS A 411
PHE A 454
SER A 508
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.47A 4ydqB-4ydqA:
54.6		 4ydqB-4ydqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 GLU A 361
THR A 478
HIS A 480
 HFG  A 802 (-2.9A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.30A 4ydqB-4ydqA:
54.6		 4ydqB-4ydqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 ALA A 290
TYR A 293
PRO A 596
 None
 0.55A 4zdyA-4ydqA:
undetectable		 4zdyA-4ydqA:
22.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 12 GLU A 392
ARG A 390
GLU A 409
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.31A 5f9zA-4ydqA:
49.8		 5f9zA-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
ARG A 390
GLU A 409
PHE A 454
SER A 508
GLY A 510
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.31A 5f9zA-4ydqA:
49.8		 5f9zA-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
ARG A 390
TRP A 407
PHE A 454
SER A 508
GLY A 510
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.64A 5f9zA-4ydqA:
49.8		 5f9zA-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_A_HFGA702_1
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
THR A 478
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.41A 5f9zA-4ydqA:
49.8		 5f9zA-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 12 GLU A 392
ARG A 390
GLU A 409
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.30A 5f9zB-4ydqA:
51.0		 5f9zB-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
ARG A 390
GLU A 409
PHE A 454
SER A 508
GLY A 510
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.35A 5f9zB-4ydqA:
51.0		 5f9zB-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
ARG A 390
TRP A 407
PHE A 454
SER A 508
GLY A 510
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.67A 5f9zB-4ydqA:
51.0		 5f9zB-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F9Z_B_HFGB703_1
(AMINOACYL-TRNA
SYNTHETASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
THR A 478
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.39A 5f9zB-4ydqA:
51.0		 5f9zB-4ydqA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 PHE A 262
TYR A 266
LEU A 287
THR A 513
ARG A 514
ILE A 516
GLY A 517
ILE A 520
MET A 521
TYR A 746
 None
None
None
None
ANP  A 801 (-3.2A)
None
None
None
None
None
 0.35A 5ifuA-4ydqA:
49.9		 5ifuA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 PHE A 262
TYR A 266
TYR A 285
ARG A 514
GLY A 517
ILE A 520
MET A 521
 None
None
None
ANP  A 801 (-3.2A)
None
None
None
 0.97A 5ifuA-4ydqA:
49.9		 5ifuA-4ydqA:
97.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 9 TYR A 266
ILE A 276
LEU A 287
THR A 513
ARG A 514
ILE A 516
GLY A 517
 None
None
None
None
ANP  A 801 (-3.2A)
None
None
 0.28A 5ifuB-4ydqA:
48.0		 5ifuB-4ydqA:
97.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 5 ARG A 514
CYH A 511
GLN A 475
ILE A 518
 ANP  A 801 (-3.2A)
None
ANP  A 801 (-4.4A)
None
 1.47A 5ki6A-4ydqA:
3.8		 5ki6A-4ydqA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 ASP A 719
ILE A 444
GLY A 446
ILE A 447
PRO A 713
 None
 1.18A 5kr2A-4ydqA:
undetectable		 5kr2A-4ydqA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 9 ASP A 719
ILE A 444
GLY A 446
ILE A 447
PRO A 713
 None
 1.08A 5kr2C-4ydqA:
undetectable		 5kr2C-4ydqA:
12.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.52A 5xioA-4ydqA:
50.6		 5xioA-4ydqA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
TRP A 407
PHE A 454
THR A 478
SER A 508
GLY A 510
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.77A 5xioA-4ydqA:
50.6		 5xioA-4ydqA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 THR A 359
GLU A 361
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
HFG  A 802 (-4.0A)
 0.13A 5xioA-4ydqA:
50.6		 5xioA-4ydqA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		8 / 12 GLU A 392
PRO A 358
THR A 359
ARG A 390
GLU A 409
HIS A 411
PHE A 454
HIS A 480
 ANP  A 801 (-3.6A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 (-4.0A)
 1.20A 5xioB-4ydqA:
50.7		 5xioB-4ydqA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
HIS A 480
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.44A 5xioB-4ydqA:
50.7		 5xioB-4ydqA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
TRP A 407
PHE A 454
THR A 478
HIS A 480
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.67A 5xioB-4ydqA:
50.7		 5xioB-4ydqA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
THR A 359
ARG A 390
HIS A 411
THR A 478
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.32A 5xipA-4ydqA:
51.8		 5xipA-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
HIS A 411
PHE A 454
THR A 478
SER A 508
GLY A 510
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.32A 5xipA-4ydqA:
51.8		 5xipA-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
HIS A 411
THR A 478
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.57A 5xipA-4ydqA:
51.8		 5xipA-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 GLU A 361
TRP A 407
HIS A 480
 HFG  A 802 (-2.9A)
None
HFG  A 802 (-4.0A)
 0.99A 5xipA-4ydqA:
50.7		 5xipA-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
THR A 359
ARG A 390
HIS A 411
PHE A 454
THR A 478
HIS A 480
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 1.23A 5xipB-4ydqA:
51.6		 5xipB-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
GLU A 361
ARG A 390
TRP A 407
HIS A 411
PHE A 454
THR A 478
HIS A 480
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-4.0A)
 0.71A 5xipB-4ydqA:
51.6		 5xipB-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 12 GLU A 392
THR A 359
GLU A 409
HIS A 411
THR A 478
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-3.7A)
 1.04A 5xipC-4ydqA:
50.6		 5xipC-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
THR A 359
GLU A 361
TRP A 407
GLU A 409
HIS A 411
PHE A 454
THR A 478
GLY A 510
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
None
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-3.7A)
 0.60A 5xipC-4ydqA:
50.6		 5xipC-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 12 VAL A 339
PRO A 358
THR A 359
GLU A 409
PHE A 486
 HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 ( 4.9A)
None
 1.19A 5xipC-4ydqA:
50.6		 5xipC-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 12 GLU A 392
THR A 359
GLU A 361
ARG A 390
GLU A 409
TRP A 509
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
None
 1.40A 5xipD-4ydqA:
50.6		 5xipD-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		12 / 12 LEU A 325
GLU A 338
VAL A 339
PRO A 358
THR A 359
GLU A 361
ARG A 390
TRP A 407
GLU A 409
PHE A 454
THR A 478
TRP A 509
 None
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
None
 0.61A 5xipD-4ydqA:
50.6		 5xipD-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		6 / 12 VAL A 339
PRO A 358
THR A 359
GLU A 409
PHE A 486
TRP A 509
 HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
HFG  A 802 ( 4.9A)
None
None
 1.34A 5xipD-4ydqA:
50.6		 5xipD-4ydqA:
63.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 1.05A 5xiqA-4ydqA:
53.1		 5xiqA-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.32A 5xiqA-4ydqA:
53.1		 5xiqA-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
TRP A 407
PHE A 454
THR A 478
SER A 508
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
HFG  A 802 (-3.7A)
 0.66A 5xiqA-4ydqA:
53.1		 5xiqA-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_A_HFGA1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
ARG A 390
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.0A)
 0.12A 5xiqA-4ydqA:
53.1		 5xiqA-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
 ANP  A 801 (-3.6A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
 1.24A 5xiqB-4ydqA:
52.6		 5xiqB-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
 0.34A 5xiqB-4ydqA:
52.6		 5xiqB-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
TRP A 407
PHE A 454
THR A 478
SER A 508
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
 0.65A 5xiqB-4ydqA:
52.6		 5xiqB-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 THR A 359
GLU A 361
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
HFG  A 802 (-4.0A)
 0.19A 5xiqB-4ydqA:
52.6		 5xiqB-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		8 / 12 GLU A 392
THR A 359
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
 ANP  A 801 (-3.6A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
 1.31A 5xiqC-4ydqA:
52.5		 5xiqC-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
SER A 508
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
 0.29A 5xiqC-4ydqA:
52.5		 5xiqC-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		10 / 12 PHE A 335
GLU A 338
VAL A 339
PRO A 358
THR A 359
ARG A 390
TRP A 407
PHE A 454
THR A 478
SER A 508
 HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 (-3.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
 0.66A 5xiqC-4ydqA:
52.5		 5xiqC-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
GLY A 510
 ANP  A 801 (-3.6A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-3.7A)
 1.32A 5xiqD-4ydqA:
52.7		 5xiqD-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
GLU A 409
HIS A 411
PHE A 454
THR A 478
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-3.7A)
 0.37A 5xiqD-4ydqA:
52.7		 5xiqD-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
ARG A 390
TRP A 407
GLU A 409
PHE A 454
THR A 478
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
ANP  A 801 ( 2.5A)
None
HFG  A 802 ( 4.9A)
HFG  A 802 (-3.6A)
HFG  A 802 ( 4.0A)
HFG  A 802 (-3.7A)
 0.66A 5xiqD-4ydqA:
52.7		 5xiqD-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		5 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
THR A 460
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
None
 1.34A 5xiqD-4ydqA:
52.7		 5xiqD-4ydqA:
65.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		3 / 3 THR A 359
GLU A 361
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
HFG  A 802 (-4.0A)
 0.16A 5xiqD-4ydqA:
52.7		 5xiqD-4ydqA:
65.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 6 VAL A 367
LEU A 380
LEU A 382
HIS A 411
 None
None
None
HFG  A 802 (-4.5A)
 0.96A 6e43B-4ydqA:
undetectable		 6e43B-4ydqA:
21.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		7 / 12 GLU A 392
GLU A 409
HIS A 411
THR A 478
SER A 508
TRP A 509
GLY A 510
 ANP  A 801 (-3.6A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
None
HFG  A 802 (-3.7A)
 1.04A 6mn8A-4ydqA:
44.3		 6mn8A-4ydqA:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		11 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
GLU A 409
HIS A 411
THR A 478
SER A 508
TRP A 509
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
HFG  A 802 ( 4.9A)
HFG  A 802 (-4.5A)
HFG  A 802 ( 4.0A)
HFG  A 802 ( 3.8A)
None
HFG  A 802 (-3.7A)
 0.43A 6mn8A-4ydqA:
44.3		 6mn8A-4ydqA:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		9 / 12 LEU A 325
PHE A 335
GLU A 338
VAL A 339
PRO A 358
TRP A 407
THR A 478
TRP A 509
GLY A 510
 None
HFG  A 802 (-3.4A)
MG  A 803 ( 4.1A)
HFG  A 802 (-4.1A)
HFG  A 802 (-4.2A)
None
HFG  A 802 ( 4.0A)
None
HFG  A 802 (-3.7A)
 0.70A 6mn8A-4ydqA:
44.3		 6mn8A-4ydqA:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MN8_A_HFGA603_1
(UNCHARACTERIZED
PROTEIN)		 4ydq PROLINE--TRNA LIGASE
(Plasmodium
falciparum) 		4 / 4 THR A 359
GLU A 361
ARG A 390
HIS A 480
 HFG  A 802 (-3.2A)
HFG  A 802 (-2.9A)
ANP  A 801 ( 2.5A)
HFG  A 802 (-4.0A)
 0.45A 6mn8A-4ydqA:
44.3		 6mn8A-4ydqA:
50.97