SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ydv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGL_L_ESTL911_1
(IG GAMMA-1-CHAIN
IG KAPPA-CHAIN)		 4ydv HIV ANTIBODY 7B2
LIGHT CHAIN,IG KAPPA
CHAIN C REGION
(Homo
sapiens) 		5 / 10 ALA L  34
TYR L  36
LEU L  46
TYR L  49
HIS L  89
 None
 0.60A 1jglH-4ydvL:
17.3
1jglL-4ydvL:
25.8		 1jglH-4ydvL:
28.57
1jglL-4ydvL:
52.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4ydv HIV ANTIBODY 7B2
LIGHT CHAIN,IG KAPPA
CHAIN C REGION
(Homo
sapiens) 		4 / 5 LEU L 179
GLY L 128
PRO L 120
VAL L 132
 None
 0.88A 2aojA-4ydvL:
undetectable		 2aojA-4ydvL:
18.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4ydv HIV ANTIBODY 7B2
HEAVY CHAIN,IGG H
CHAIN
HIV ANTIBODY 7B2
LIGHT CHAIN,IG KAPPA
CHAIN C REGION
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR L  36
PRO L  44
TYR L  87
TYR H  91
 None
 0.73A 2oldA-4ydvL:
15.6
2oldB-4ydvL:
19.9		 2oldA-4ydvL:
39.48
2oldB-4ydvL:
39.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ydv HIV ANTIBODY 7B2
HEAVY CHAIN,IGG H
CHAIN
(Homo
sapiens) 		3 / 3 THR H 110
GLU H 148
HIS H 200
 None
 0.78A 3g1uB-4ydvH:
undetectable		 3g1uB-4ydvH:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4ydv HIV ANTIBODY 7B2
HEAVY CHAIN,IGG H
CHAIN
(Homo
sapiens) 		4 / 6 LEU H 189
GLY H 190
ALA H 125
PRO H 126
 None
 0.53A 3huoA-4ydvH:
undetectable		 3huoA-4ydvH:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ydv HIV ANTIBODY 7B2
HEAVY CHAIN,IGG H
CHAIN
(Homo
sapiens) 		5 / 11 VAL H   2
MET H  34
ARG H  71
ASN H  72
VAL H  75
 None
 0.66A 3qxvC-4ydvH:
19.3		 3qxvC-4ydvH:
37.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 4ydv HIV ANTIBODY 7B2
LIGHT CHAIN,IG KAPPA
CHAIN C REGION
(Homo
sapiens) 		4 / 6 ASP L 170
THR L 172
TYR L 140
THR L 109
 None
 1.41A 5b6iB-4ydvL:
undetectable		 5b6iB-4ydvL:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 4ydv HIV ANTIBODY 7B2
LIGHT CHAIN,IG KAPPA
CHAIN C REGION
(Homo
sapiens) 		4 / 8 THR L  74
SER L  63
THR L  72
SER L  65
 None
 0.95A 5l4eA-4ydvL:
undetectable
5l4eB-4ydvL:
3.1
5l4eC-4ydvL:
undetectable
5l4eD-4ydvL:
undetectable
5l4eE-4ydvL:
undetectable		 5l4eA-4ydvL:
21.41
5l4eB-4ydvL:
21.41
5l4eC-4ydvL:
21.41
5l4eD-4ydvL:
21.41
5l4eE-4ydvL:
21.41