SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ye9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 1v54A-4ye9A:
undetectable
1v54C-4ye9A:
undetectable		 1v54A-4ye9A:
19.70
1v54C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 1v54A-4ye9A:
undetectable
1v54C-4ye9A:
undetectable		 1v54A-4ye9A:
19.70
1v54C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.34A 1v54N-4ye9A:
undetectable
1v54P-4ye9A:
undetectable		 1v54N-4ye9A:
19.70
1v54P-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 1v54N-4ye9A:
undetectable
1v54P-4ye9A:
undetectable		 1v54N-4ye9A:
19.70
1v54P-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 1v55A-4ye9A:
undetectable
1v55C-4ye9A:
undetectable		 1v55A-4ye9A:
19.70
1v55C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 1v55A-4ye9A:
undetectable
1v55C-4ye9A:
undetectable		 1v55A-4ye9A:
19.70
1v55C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.35A 2dyrA-4ye9A:
undetectable
2dyrC-4ye9A:
undetectable		 2dyrA-4ye9A:
19.70
2dyrC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 2dyrA-4ye9A:
undetectable
2dyrC-4ye9A:
undetectable		 2dyrA-4ye9A:
19.70
2dyrC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.34A 2dyrN-4ye9A:
1.4
2dyrP-4ye9A:
undetectable		 2dyrN-4ye9A:
19.70
2dyrP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 2dyrN-4ye9A:
1.4
2dyrP-4ye9A:
undetectable		 2dyrN-4ye9A:
19.70
2dyrP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 2dysA-4ye9A:
undetectable
2dysC-4ye9A:
undetectable		 2dysA-4ye9A:
19.70
2dysC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.43A 2dysA-4ye9A:
undetectable
2dysC-4ye9A:
undetectable		 2dysA-4ye9A:
19.70
2dysC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 2eijA-4ye9A:
undetectable
2eijC-4ye9A:
undetectable		 2eijA-4ye9A:
19.70
2eijC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.41A 2eijA-4ye9A:
undetectable
2eijC-4ye9A:
undetectable		 2eijA-4ye9A:
19.70
2eijC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 2eijN-4ye9A:
undetectable
2eijP-4ye9A:
undetectable		 2eijN-4ye9A:
19.70
2eijP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 2eijN-4ye9A:
undetectable
2eijP-4ye9A:
undetectable		 2eijN-4ye9A:
19.70
2eijP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 2eikA-4ye9A:
1.4
2eikC-4ye9A:
undetectable		 2eikA-4ye9A:
19.70
2eikC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 2eikA-4ye9A:
1.4
2eikC-4ye9A:
undetectable		 2eikA-4ye9A:
19.70
2eikC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.33A 2eikN-4ye9A:
undetectable
2eikP-4ye9A:
undetectable		 2eikN-4ye9A:
19.70
2eikP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 2eikN-4ye9A:
undetectable
2eikP-4ye9A:
undetectable		 2eikN-4ye9A:
19.70
2eikP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 2eilA-4ye9A:
undetectable
2eilC-4ye9A:
undetectable		 2eilA-4ye9A:
19.70
2eilC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.43A 2eilA-4ye9A:
undetectable
2eilC-4ye9A:
undetectable		 2eilA-4ye9A:
19.70
2eilC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 2eilN-4ye9A:
undetectable
2eilP-4ye9A:
undetectable		 2eilN-4ye9A:
19.70
2eilP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 2eilN-4ye9A:
undetectable
2eilP-4ye9A:
undetectable		 2eilN-4ye9A:
19.70
2eilP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.32A 2eimA-4ye9A:
undetectable
2eimC-4ye9A:
undetectable		 2eimA-4ye9A:
19.70
2eimC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.35A 2eimA-4ye9A:
undetectable
2eimC-4ye9A:
undetectable		 2eimA-4ye9A:
19.70
2eimC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.43A 2eimN-4ye9A:
undetectable
2eimP-4ye9A:
undetectable		 2eimN-4ye9A:
19.70
2eimP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.44A 2eimN-4ye9A:
undetectable
2eimP-4ye9A:
undetectable		 2eimN-4ye9A:
19.70
2eimP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 2einA-4ye9A:
undetectable
2einC-4ye9A:
undetectable		 2einA-4ye9A:
19.70
2einC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 2einA-4ye9A:
undetectable
2einC-4ye9A:
undetectable		 2einA-4ye9A:
19.70
2einC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.35A 2einN-4ye9A:
undetectable
2einP-4ye9A:
undetectable		 2einN-4ye9A:
19.70
2einP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.34A 2einN-4ye9A:
undetectable
2einP-4ye9A:
undetectable		 2einN-4ye9A:
19.70
2einP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 5 LEU A 402
ASP A 414
MET A 380
LEU A 384
 None
 1.30A 2jfaA-4ye9A:
undetectable		 2jfaA-4ye9A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 10 ARG A 267
PHE A 268
ILE A 284
GLY A 289
PHE A 288
 None
 1.17A 2tsrC-4ye9A:
undetectable		 2tsrC-4ye9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 2zxwA-4ye9A:
undetectable
2zxwC-4ye9A:
undetectable		 2zxwA-4ye9A:
19.70
2zxwC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.41A 2zxwA-4ye9A:
undetectable
2zxwC-4ye9A:
undetectable		 2zxwA-4ye9A:
19.70
2zxwC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.35A 2zxwN-4ye9A:
undetectable
2zxwP-4ye9A:
undetectable		 2zxwN-4ye9A:
19.70
2zxwP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 2zxwN-4ye9A:
undetectable
2zxwP-4ye9A:
undetectable		 2zxwN-4ye9A:
19.70
2zxwP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 3abkA-4ye9A:
undetectable
3abkC-4ye9A:
undetectable		 3abkA-4ye9A:
19.70
3abkC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.42A 3abkA-4ye9A:
undetectable
3abkC-4ye9A:
undetectable		 3abkA-4ye9A:
19.70
3abkC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 3ag1A-4ye9A:
undetectable
3ag1C-4ye9A:
undetectable		 3ag1A-4ye9A:
19.70
3ag1C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 3ag1A-4ye9A:
undetectable
3ag1C-4ye9A:
undetectable		 3ag1A-4ye9A:
19.70
3ag1C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 3ag2A-4ye9A:
1.4
3ag2C-4ye9A:
undetectable		 3ag2A-4ye9A:
19.70
3ag2C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 3ag2A-4ye9A:
1.4
3ag2C-4ye9A:
undetectable		 3ag2A-4ye9A:
19.70
3ag2C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 3ag2N-4ye9A:
undetectable
3ag2P-4ye9A:
undetectable		 3ag2N-4ye9A:
19.70
3ag2P-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 3ag2N-4ye9A:
undetectable
3ag2P-4ye9A:
undetectable		 3ag2N-4ye9A:
19.70
3ag2P-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 3ag3A-4ye9A:
undetectable
3ag3C-4ye9A:
undetectable		 3ag3A-4ye9A:
19.70
3ag3C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.45A 3ag3A-4ye9A:
undetectable
3ag3C-4ye9A:
undetectable		 3ag3A-4ye9A:
19.70
3ag3C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 3ag4A-4ye9A:
undetectable
3ag4C-4ye9A:
undetectable		 3ag4A-4ye9A:
19.70
3ag4C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.42A 3ag4A-4ye9A:
undetectable
3ag4C-4ye9A:
undetectable		 3ag4A-4ye9A:
19.70
3ag4C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 3asnA-4ye9A:
undetectable
3asnC-4ye9A:
undetectable		 3asnA-4ye9A:
19.70
3asnC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.40A 3asnA-4ye9A:
undetectable
3asnC-4ye9A:
undetectable		 3asnA-4ye9A:
19.70
3asnC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 11 MET A 221
LEU A 224
LEU A 229
LEU A 455
GLY A 296
 None
 1.32A 3hm1B-4ye9A:
undetectable		 3hm1B-4ye9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 8 GLY A  53
LEU A  55
LEU A  56
ILE A  76
 None
 0.88A 3nbqB-4ye9A:
undetectable		 3nbqB-4ye9A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		3 / 3 ARG A 391
PRO A 436
PHE A 387
 None
 0.92A 3thrC-4ye9A:
undetectable		 3thrC-4ye9A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		3 / 3 ARG A 154
GLU A  84
THR A  83
 None
 0.84A 3v4tA-4ye9A:
undetectable		 3v4tA-4ye9A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 12 PHE A 268
ILE A 284
GLY A 289
PHE A 288
ALA A 537
 None
 1.09A 4eb4A-4ye9A:
undetectable		 4eb4A-4ye9A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 12 PHE A 268
ILE A 284
GLY A 289
PHE A 288
ALA A 537
 None
 1.10A 4eb4B-4ye9A:
undetectable		 4eb4B-4ye9A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 12 ILE A 499
ILE A 532
LEU A 325
GLY A 279
ILE A 278
 None
 1.05A 4o1eA-4ye9A:
undetectable		 4o1eA-4ye9A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 5b1bN-4ye9A:
undetectable
5b1bP-4ye9A:
undetectable		 5b1bN-4ye9A:
19.70
5b1bP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 5b1bN-4ye9A:
undetectable
5b1bP-4ye9A:
undetectable		 5b1bN-4ye9A:
19.70
5b1bP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 5b3sN-4ye9A:
1.3
5b3sP-4ye9A:
undetectable		 5b3sN-4ye9A:
19.70
5b3sP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 5b3sN-4ye9A:
1.3
5b3sP-4ye9A:
undetectable		 5b3sN-4ye9A:
19.70
5b3sP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 5iy5A-4ye9A:
undetectable
5iy5C-4ye9A:
undetectable		 5iy5A-4ye9A:
19.70
5iy5C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 5iy5A-4ye9A:
undetectable
5iy5C-4ye9A:
undetectable		 5iy5A-4ye9A:
19.70
5iy5C-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 5 ARG A 267
GLN A 481
PRO A 479
ILE A 451
 None
 1.48A 5ki6A-4ye9A:
undetectable		 5ki6A-4ye9A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 8 THR A 457
ASN A 287
PHE A 268
PRO A 269
 None
 1.12A 5v4vA-4ye9A:
undetectable		 5v4vA-4ye9A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 8 THR A 457
ASN A 287
PHE A 268
PRO A 269
 None
 1.13A 5v4vB-4ye9A:
undetectable		 5v4vB-4ye9A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 8 GLY A 411
ARG A 376
GLN A 360
ASP A 414
 None
 1.04A 5vlmB-4ye9A:
undetectable		 5vlmB-4ye9A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 12 ARG A 267
PHE A 268
GLY A 289
PHE A 288
ALA A 537
 None
 1.19A 5x66A-4ye9A:
undetectable
5x66B-4ye9A:
undetectable		 5x66A-4ye9A:
16.07
5x66B-4ye9A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 12 PHE A 268
ILE A 284
GLY A 289
PHE A 288
ALA A 537
 None
 1.11A 5x66A-4ye9A:
undetectable
5x66B-4ye9A:
undetectable		 5x66A-4ye9A:
16.07
5x66B-4ye9A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 10 PHE A 268
ILE A 284
GLY A 289
PHE A 288
ALA A 537
 None
 1.16A 5x66D-4ye9A:
undetectable		 5x66D-4ye9A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		5 / 12 PHE A 268
ILE A 284
GLY A 289
PHE A 288
ALA A 537
 None
 1.14A 5x66F-4ye9A:
undetectable		 5x66F-4ye9A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		3 / 3 THR A 333
GLU A 449
HIS A 442
 None
 0.81A 5xioA-4ye9A:
undetectable		 5xioA-4ye9A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		3 / 3 THR A 333
GLU A 449
HIS A 442
 None
 0.78A 5xiqB-4ye9A:
undetectable		 5xiqB-4ye9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		3 / 3 THR A 333
GLU A 449
HIS A 442
 None
 0.83A 5xiqD-4ye9A:
undetectable		 5xiqD-4ye9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.35A 5zcqN-4ye9A:
undetectable
5zcqP-4ye9A:
undetectable		 5zcqN-4ye9A:
19.70
5zcqP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 5zcqN-4ye9A:
undetectable
5zcqP-4ye9A:
undetectable		 5zcqN-4ye9A:
19.70
5zcqP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.36A 6nknA-4ye9A:
undetectable
6nknC-4ye9A:
undetectable		 6nknA-4ye9A:
19.70
6nknC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 6 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.38A 6nknA-4ye9A:
undetectable
6nknC-4ye9A:
undetectable		 6nknA-4ye9A:
19.70
6nknC-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.37A 6nmfN-4ye9A:
undetectable
6nmfP-4ye9A:
undetectable		 6nmfN-4ye9A:
19.70
6nmfP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.39A 6nmfN-4ye9A:
undetectable
6nmfP-4ye9A:
undetectable		 6nmfN-4ye9A:
19.70
6nmfP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 ASP A 439
TYR A 440
TRP A 432
HIS A 425
 None
 1.32A 6nmpN-4ye9A:
undetectable
6nmpP-4ye9A:
undetectable		 6nmpN-4ye9A:
19.70
6nmpP-4ye9A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ye9 GLUTAMINE--TRNA
LIGASE
(Homo
sapiens) 		4 / 7 THR A 441
TYR A 440
TRP A 432
HIS A 425
 None
 1.35A 6nmpN-4ye9A:
undetectable
6nmpP-4ye9A:
undetectable		 6nmpN-4ye9A:
19.70
6nmpP-4ye9A:
16.00