SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yeh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 4yeh LECTIN
(Cicer
arietinum) 		4 / 8 SER A  67
PHE A  21
ALA A  75
ILE A  86
 None
 1.17A 1pnlA-4yehA:
undetectable
1pnlB-4yehA:
undetectable		 1pnlA-4yehA:
19.33
1pnlB-4yehA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4yeh LECTIN
(Cicer
arietinum) 		4 / 5 LEU A  20
PRO A  44
VAL A  27
ILE A  22
 None
 0.97A 2aoiB-4yehA:
undetectable		 2aoiB-4yehA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4yeh LECTIN
(Cicer
arietinum) 		3 / 3 LYS A 181
ASP A  38
ASN A  16
 None
 1.01A 2bm9A-4yehA:
undetectable		 2bm9A-4yehA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4yeh LECTIN
(Cicer
arietinum) 		5 / 12 PHE A 161
PHE A 135
LEU A 187
ALA A 178
TYR A 133
 None
 1.41A 3apxA-4yehA:
undetectable		 3apxA-4yehA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 4yeh LECTIN
(Cicer
arietinum) 		4 / 8 LYS A 136
ASN A  81
LYS A 103
PRO A 101
 None
 1.47A 3bjwD-4yehA:
undetectable		 3bjwD-4yehA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4yeh LECTIN
(Cicer
arietinum) 		4 / 5 ILE A  98
THR A  70
PHE A  68
PHE A  78
 None
 1.33A 3em0A-4yehA:
undetectable		 3em0A-4yehA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4yeh LECTIN
(Cicer
arietinum) 		4 / 8 ASN A  23
LEU A  20
ALA A   8
SER A 175
 None
 0.87A 3kp6A-4yehA:
undetectable		 3kp6A-4yehA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4yeh LECTIN
(Cicer
arietinum) 		4 / 8 PHE A 124
ILE A 196
PHE A 135
GLY A 160
 None
 0.90A 4fgjA-4yehA:
undetectable
4fgjB-4yehA:
undetectable		 4fgjA-4yehA:
21.96
4fgjB-4yehA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4yeh LECTIN
(Cicer
arietinum) 		4 / 7 ALA A  18
ASP A 174
ILE A   6
ILE A 224
 None
 0.96A 6fbnA-4yehA:
undetectable		 6fbnA-4yehA:
20.26