SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 127
ALA A 130
LEU A 112
ASN A 111
ALA A  90
 None
 1.14A 1sa1A-4yeiA:
undetectable
1sa1B-4yeiA:
undetectable		 1sa1A-4yeiA:
17.90
1sa1B-4yeiA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 127
ALA A 130
LEU A 112
ASN A 111
ALA A  90
 None
 1.13A 1sa1C-4yeiA:
undetectable
1sa1D-4yeiA:
undetectable		 1sa1C-4yeiA:
17.90
1sa1D-4yeiA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ARG A  69
GLY A  89
ALA A  90
HIS A 108
 None
 0.93A 1wmqA-4yeiA:
undetectable		 1wmqA-4yeiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ARG A  69
GLY A  89
ALA A  90
HIS A 108
 None
 0.93A 1wmqB-4yeiA:
undetectable		 1wmqB-4yeiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ARG A  69
GLY A  89
ALA A  90
HIS A 108
 None
 0.91A 1wpuA-4yeiA:
undetectable		 1wpuA-4yeiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ARG A  69
GLY A  89
ALA A  90
HIS A 108
 None
 0.92A 1wpuB-4yeiA:
undetectable		 1wpuB-4yeiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ARG A  69
GLY A  89
ALA A  90
HIS A 108
 None
 0.94A 1wrqA-4yeiA:
undetectable		 1wrqA-4yeiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ARG A  69
GLY A  89
ALA A  90
HIS A 108
 None
 0.93A 1wrqB-4yeiA:
undetectable		 1wrqB-4yeiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A  67
GLY A  89
LEU A 107
LEU A  72
LEU A  52
 None
 1.12A 2zbpA-4yeiA:
undetectable		 2zbpA-4yeiA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 177
LEU A 142
GLY A 154
ALA A 155
LEU A 132
 None
 1.12A 3n8xB-4yeiA:
undetectable		 3n8xB-4yeiA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 182
LEU A 147
GLY A 159
ALA A 160
LEU A 137
 None
 1.05A 3n8xB-4yeiA:
undetectable		 3n8xB-4yeiA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 172
LEU A 137
GLY A 149
ALA A 150
LEU A 127
 None
 1.08A 3nt1B-4yeiA:
undetectable		 3nt1B-4yeiA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 172
LEU A 137
GLY A 149
ALA A 150
LEU A 127
 None
 1.16A 3pghA-4yeiA:
undetectable		 3pghA-4yeiA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 185
THR A 187
LEU A 192
LEU A 177
 None
 0.87A 4ejgB-4yeiA:
undetectable		 4ejgB-4yeiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4yei BETA1MUT
(synthetic
construct) 		4 / 6 ALA A  90
ASN A  91
LEU A  72
GLU A  94
 None
 0.87A 4g24A-4yeiA:
undetectable		 4g24A-4yeiA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 ALA A  75
LEU A  52
ILE A  40
ALA A  60
ILE A  26
 None
 0.90A 4o2bD-4yeiA:
undetectable		 4o2bD-4yeiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 4yei BETA1MUT
(synthetic
construct) 		4 / 7 GLY A 149
ALA A 170
GLU A 169
SER A 211
 None
 0.64A 4r1zB-4yeiA:
undetectable		 4r1zB-4yeiA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A  95
ASN A  91
LEU A  87
ALA A  50
 None
 0.71A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 100
ASN A  96
LEU A  92
ALA A  55
 None
 0.63A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 105
ASN A 101
LEU A  97
ALA A  60
 None
 0.70A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 125
ASN A 121
LEU A 117
ALA A  80
 None
 0.72A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 130
ASN A 126
LEU A 122
ALA A  85
 None
 0.69A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 135
ASN A 131
LEU A 127
ALA A  90
 None
 0.74A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 140
ASN A 136
LEU A 132
ALA A  95
 None
 0.68A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 160
ASN A 156
LEU A 152
ALA A 115
 None
 0.75A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 165
ASN A 161
LEU A 157
ALA A 120
 None
 0.73A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 170
ASN A 166
LEU A 162
ALA A 125
 None
 0.71A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4yei BETA1MUT
(synthetic
construct) 		4 / 8 ALA A 180
ASN A 176
LEU A 172
ALA A 135
 None
 0.65A 4wboB-4yeiA:
undetectable		 4wboB-4yeiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4yei BETA1MUT
(synthetic
construct) 		5 / 10 LEU A  87
LEU A 107
ASN A 101
SER A  83
ALA A  95
 None
 1.14A 4xj7C-4yeiA:
undetectable
4xj7D-4yeiA:
undetectable		 4xj7C-4yeiA:
27.43
4xj7D-4yeiA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4yei BETA1MUT
(synthetic
construct) 		5 / 10 LEU A 117
LEU A 137
ASN A 131
SER A 113
ALA A 125
 None
 1.04A 4xj7C-4yeiA:
undetectable
4xj7D-4yeiA:
undetectable		 4xj7C-4yeiA:
27.43
4xj7D-4yeiA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yei BETA1MUT
(synthetic
construct) 		6 / 9 LEU A 107
ALA A 130
LEU A 117
ALA A 115
LEU A  97
ALA A 110
 None
 1.20A 4z91F-4yeiA:
undetectable
4z91G-4yeiA:
undetectable
4z91H-4yeiA:
undetectable
4z91I-4yeiA:
undetectable
4z91J-4yeiA:
undetectable		 4z91F-4yeiA:
20.19
4z91G-4yeiA:
20.19
4z91H-4yeiA:
20.19
4z91I-4yeiA:
20.19
4z91J-4yeiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yei BETA1MUT
(synthetic
construct) 		6 / 9 LEU A 132
ALA A 130
LEU A 112
ALA A 110
LEU A 102
ALA A 125
 None
 1.22A 4z91F-4yeiA:
undetectable
4z91G-4yeiA:
undetectable
4z91H-4yeiA:
undetectable
4z91I-4yeiA:
undetectable
4z91J-4yeiA:
undetectable		 4z91F-4yeiA:
20.19
4z91G-4yeiA:
20.19
4z91H-4yeiA:
20.19
4z91I-4yeiA:
20.19
4z91J-4yeiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yei BETA1MUT
(synthetic
construct) 		6 / 9 LEU A 152
ALA A 150
LEU A 142
ALA A 165
LEU A 172
ALA A 170
 None
 1.25A 4z91F-4yeiA:
undetectable
4z91G-4yeiA:
undetectable
4z91H-4yeiA:
undetectable
4z91I-4yeiA:
undetectable
4z91J-4yeiA:
undetectable		 4z91F-4yeiA:
20.19
4z91G-4yeiA:
20.19
4z91H-4yeiA:
20.19
4z91I-4yeiA:
20.19
4z91J-4yeiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yei BETA1MUT
(synthetic
construct) 		6 / 9 LEU A 172
ALA A 170
LEU A 152
ALA A 150
LEU A 142
ALA A 165
 None
 1.20A 4z91F-4yeiA:
undetectable
4z91G-4yeiA:
undetectable
4z91H-4yeiA:
undetectable
4z91I-4yeiA:
undetectable
4z91J-4yeiA:
undetectable		 4z91F-4yeiA:
20.19
4z91G-4yeiA:
20.19
4z91H-4yeiA:
20.19
4z91I-4yeiA:
20.19
4z91J-4yeiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yei BETA1MUT
(synthetic
construct) 		6 / 9 LEU A 177
LEU A 192
ALA A 190
ALA A 170
LEU A 152
LEU A 157
 None
 1.26A 4z91F-4yeiA:
undetectable
4z91G-4yeiA:
undetectable
4z91H-4yeiA:
undetectable
4z91I-4yeiA:
undetectable
4z91J-4yeiA:
undetectable		 4z91F-4yeiA:
20.19
4z91G-4yeiA:
20.19
4z91H-4yeiA:
20.19
4z91I-4yeiA:
20.19
4z91J-4yeiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 ALA A  75
LEU A  52
ILE A  40
ALA A  60
ILE A  26
 None
 0.91A 5eypB-4yeiA:
undetectable		 5eypB-4yeiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 102
LEU A  42
MET A  21
ALA A  75
LEU A  52
 None
 1.23A 5ienA-4yeiA:
undetectable		 5ienA-4yeiA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A  42
MET A  21
LEU A  87
ALA A  75
LEU A  52
 None
 1.18A 5ienB-4yeiA:
undetectable		 5ienB-4yeiA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 182
LEU A 147
GLY A 159
ALA A 160
LEU A 137
 None
 1.11A 5ikrB-4yeiA:
undetectable		 5ikrB-4yeiA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A  97
LEU A 137
ALA A 135
LEU A 112
ASN A 131
 None
 1.12A 5itzB-4yeiA:
undetectable		 5itzB-4yeiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 127
LEU A 167
ALA A 165
LEU A 142
ASN A 161
 None
 1.08A 5itzB-4yeiA:
undetectable		 5itzB-4yeiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 172
LEU A 137
GLY A 149
ALA A 150
LEU A 127
 None
 1.02A 5jvzA-4yeiA:
undetectable		 5jvzA-4yeiA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 LEU A 172
LEU A 137
GLY A 149
ALA A 150
LEU A 127
 None
 1.00A 5jvzB-4yeiA:
undetectable		 5jvzB-4yeiA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 4yei BETA1MUT
(synthetic
construct) 		5 / 12 ALA A 115
GLY A 114
SER A 113
LEU A 102
ARG A  73
 None
 0.95A 5w7pA-4yeiA:
undetectable		 5w7pA-4yeiA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 4yei BETA1MUT
(synthetic
construct) 		5 / 9 LEU A  27
VAL A  23
SER A  68
LEU A  67
ILE A  45
 None
 1.20A 6fdyU-4yeiA:
undetectable		 6fdyU-4yeiA:
23.73