SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yet'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 6 TRP A 160
GLY A 143
ASN A  66
PRO A 145
 None
 1.23A 1dedA-4yetA:
undetectable		 1dedA-4yetA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 7 TYR A  28
HIS A  74
HIS A  31
TYR A  35
 None
FE  A 300 (-3.3A)
None
None
 1.28A 2ombC-4yetA:
undetectable
2ombD-4yetA:
undetectable		 2ombC-4yetA:
22.27
2ombD-4yetA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 7 GLU A  88
TRP A 185
LEU A 155
TRP A 179
 None
 1.37A 3k8mB-4yetA:
undetectable		 3k8mB-4yetA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 6 ILE A  57
ASN A  73
PRO A 153
LEU A 146
 None
 1.26A 3oi8A-4yetA:
undetectable		 3oi8A-4yetA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 5 PHE A 107
LEU A 115
GLY A 124
VAL A 127
 None
 1.02A 3wrkD-4yetA:
undetectable		 3wrkD-4yetA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 6 TYR A 175
HIS A  27
HIS A  74
TYR A  77
 None
FE  A 300 (-3.3A)
FE  A 300 (-3.3A)
None
 1.49A 4df2A-4yetA:
undetectable		 4df2A-4yetA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		5 / 9 VAL A 159
LEU A 155
LEU A 114
LEU A 126
ILE A 136
 None
 1.36A 4ubsA-4yetA:
1.7		 4ubsA-4yetA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		4 / 8 TRP A 160
TRP A 125
HIS A  74
THR A  61
 None
None
FE  A 300 (-3.3A)
None
 1.11A 5hqaA-4yetA:
undetectable		 5hqaA-4yetA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		3 / 3 ALA A 188
ASN A 191
LEU A 192
 None
 0.39A 5i1nB-4yetA:
undetectable		 5i1nB-4yetA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		3 / 3 ALA A 188
ASN A 191
LEU A 192
 None
 0.31A 5i1oC-4yetA:
undetectable		 5i1oC-4yetA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4yet SUPEROXIDE DISMUTASE
(Babesia
bovis) 		3 / 3 ALA A 188
ASN A 191
LEU A 192
 None
 0.31A 5i1pA-4yetA:
undetectable		 5i1pA-4yetA:
12.14