SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		3 / 3 TRP A  72
VAL A  73
PRO A  74
 None
 0.39A 1rg1A-4yeuA:
undetectable		 1rg1A-4yeuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		3 / 3 TRP A  72
VAL A  73
PRO A  74
 None
 0.38A 1rh0A-4yeuA:
undetectable		 1rh0A-4yeuA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 8 ILE A  39
VAL A  73
SER A  84
THR A  87
TYR A 102
 None
 0.59A 2yoeB-4yeuA:
29.5
2yoeC-4yeuA:
29.6		 2yoeB-4yeuA:
71.88
2yoeC-4yeuA:
71.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 VAL A  35
GLY A 108
PRO A  85
THR A  87
GLY A  88
 None
 1.15A 3bjwG-4yeuA:
1.2		 3bjwG-4yeuA:
17.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 9 PRO A 120
ILE A 208
ILE A 209
TYR A 261
THR A 262
ILE A 265
 None
 0.76A 3p4wA-4yeuA:
19.9		 3p4wA-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 TYR A 204
ILE A 208
ILE A 209
THR A 262
ILE A 265
 None
 0.80A 3p4wA-4yeuA:
19.9		 3p4wA-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 9 PRO A 120
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
ILE A 266
 None
 0.75A 3p4wB-4yeuA:
19.9		 3p4wB-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 9 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
ILE A 266
 None
 0.78A 3p4wB-4yeuA:
19.9		 3p4wB-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 TYR A 204
ILE A 208
ILE A 209
MET A 212
VAL A 249
 None
 1.15A 3p4wB-4yeuA:
19.9		 3p4wB-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 8 ILE A 208
ILE A 209
THR A 262
ILE A 265
 None
 0.42A 3p4wC-4yeuA:
19.9		 3p4wC-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 8 PRO A 120
ILE A 208
ILE A 209
THR A 262
 None
 0.82A 3p4wC-4yeuA:
19.9		 3p4wC-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		8 / 10 PRO A 120
ILE A 208
ILE A 209
MET A 212
TYR A 261
THR A 262
ILE A 265
ILE A 266
 None
 0.74A 3p4wD-4yeuA:
19.9		 3p4wD-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
ILE A 266
 None
 0.76A 3p4wD-4yeuA:
19.9		 3p4wD-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
VAL A 249
 None
 1.14A 3p4wD-4yeuA:
19.9		 3p4wD-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		8 / 10 PRO A 120
ILE A 208
ILE A 209
MET A 212
TYR A 261
THR A 262
ILE A 265
ILE A 266
 None
 0.74A 3p4wE-4yeuA:
19.9		 3p4wE-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 266
 None
 0.79A 3p4wE-4yeuA:
19.9		 3p4wE-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
VAL A 249
 None
 1.16A 3p4wE-4yeuA:
19.9		 3p4wE-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
ASN A 314
 None
 0.59A 3p50A-4yeuA:
20.0		 3p50A-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PRO A 120
ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
 None
 0.82A 3p50A-4yeuA:
20.0		 3p50A-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
ASN A 314
 None
 0.59A 3p50B-4yeuA:
19.9		 3p50B-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PRO A 120
ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
 None
 0.82A 3p50B-4yeuA:
19.9		 3p50B-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
ASN A 314
 None
 0.59A 3p50C-4yeuA:
19.9		 3p50C-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PRO A 120
ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
 None
 0.82A 3p50C-4yeuA:
19.9		 3p50C-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
ASN A 314
 None
 0.60A 3p50D-4yeuA:
19.9		 3p50D-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PRO A 120
ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
 None
 0.83A 3p50D-4yeuA:
19.9		 3p50D-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
ASN A 314
 None
 0.60A 3p50E-4yeuA:
19.9		 3p50E-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PRO A 120
ILE A 209
LEU A 213
TYR A 261
THR A 262
ILE A 265
 None
 0.83A 3p50E-4yeuA:
19.9		 3p50E-4yeuA:
52.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 8 GLU A  77
GLU A 131
TYR A 175
PHE A 188
 None
 0.94A 3rqwC-4yeuA:
29.9
3rqwD-4yeuA:
30.0		 3rqwC-4yeuA:
71.25
3rqwD-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 8 ILE A  79
GLU A 131
TYR A 175
PHE A 188
 None
 0.71A 3rqwI-4yeuA:
29.9
3rqwJ-4yeuA:
30.0		 3rqwI-4yeuA:
71.25
3rqwJ-4yeuA:
71.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ALA A 104
ILE A  63
ILE A 101
PRO A  74
LEU A  76
 None
 1.16A 3u7sB-4yeuA:
undetectable		 3u7sB-4yeuA:
15.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 7 GLU A  77
ILE A  79
GLU A 131
PHE A 133
TYR A 175
 None
 0.69A 4a97A-4yeuA:
29.6		 4a97A-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 7 ILE A  79
GLU A 131
PHE A 133
TYR A 175
HIS A 177
 None
 0.60A 4a97A-4yeuA:
29.6		 4a97A-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PHE A  19
TYR A  38
VAL A  40
ARG A  91
ILE A 101
ASN A 103
 None
 0.57A 4a97E-4yeuA:
29.4		 4a97E-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 12 PHE A  19
TYR A  38
ARG A  91
ILE A 101
ASN A 103
 None
 0.52A 4a97A-4yeuA:
29.6
4a97B-4yeuA:
29.2		 4a97A-4yeuA:
71.88
4a97B-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 12 GLU A  77
ILE A  79
GLU A 131
TYR A 175
HIS A 177
 None
 0.78A 4a97B-4yeuA:
27.0
4a97C-4yeuA:
29.4		 4a97B-4yeuA:
71.88
4a97C-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 12 PHE A  19
VAL A  40
ARG A  91
ILE A 101
ASN A 103
 None
 0.48A 4a97B-4yeuA:
27.0
4a97C-4yeuA:
29.4		 4a97B-4yeuA:
71.88
4a97C-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 8 PHE A  19
TYR A  38
VAL A  40
ARG A  91
MET A  93
ILE A 101
ASN A 103
 None
 0.64A 4a97C-4yeuA:
29.4		 4a97C-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 GLU A  77
ILE A  79
GLU A 131
PHE A 133
TYR A 175
HIS A 177
 None
 0.70A 4a97D-4yeuA:
29.5		 4a97D-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 8 PHE A  19
TYR A  38
VAL A  40
ARG A  91
ILE A 101
ASN A 103
 None
 0.55A 4a97D-4yeuA:
29.5		 4a97D-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 8 PHE A  19
VAL A  40
ARG A  91
MET A  93
ILE A 101
 None
 0.65A 4a97D-4yeuA:
29.5		 4a97D-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 6 GLU A 131
PHE A 133
TYR A 175
HIS A 177
PHE A 188
 None
 0.63A 4a97E-4yeuA:
29.4		 4a97E-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 12 GLU A  77
GLU A 131
PHE A 133
TYR A 175
HIS A 177
 None
 0.85A 4a97F-4yeuA:
29.6
4a97J-4yeuA:
29.6		 4a97F-4yeuA:
71.88
4a97J-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 12 PHE A  19
TYR A  38
ARG A  91
MET A  93
ILE A 101
ASN A 103
 None
 0.72A 4a97F-4yeuA:
29.6
4a97J-4yeuA:
29.6		 4a97F-4yeuA:
71.88
4a97J-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_G_ZPCG1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 12 GLU A  77
GLU A 131
TYR A 175
HIS A 177
PHE A 188
 None
 0.75A 4a97F-4yeuA:
29.6
4a97G-4yeuA:
29.4		 4a97F-4yeuA:
71.88
4a97G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_G_ZPCG1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 12 PHE A  19
TYR A  38
ARG A  91
MET A  93
ILE A 101
ASN A 103
 None
 0.66A 4a97F-4yeuA:
29.6
4a97G-4yeuA:
29.4		 4a97F-4yeuA:
71.88
4a97G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 8 PHE A  19
TYR A  38
VAL A  40
ARG A  91
MET A  93
ILE A 101
ASN A 103
 None
 0.61A 4a97G-4yeuA:
29.4		 4a97G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 GLU A  77
ILE A  79
GLU A 131
TYR A 175
HIS A 177
PHE A 188
 None
 0.72A 4a97H-4yeuA:
29.4		 4a97H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PHE A  19
TYR A  38
VAL A  40
ARG A  91
ILE A 101
ASN A 103
 None
 0.56A 4a97H-4yeuA:
29.4		 4a97H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 6 GLU A  77
ILE A  79
PHE A 133
TYR A 175
HIS A 177
 None
 0.75A 4a97I-4yeuA:
29.5		 4a97I-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 8 PHE A  19
TYR A  38
VAL A  40
ARG A  91
MET A  93
ILE A 101
ASN A 103
 None
 0.60A 4a97I-4yeuA:
29.5		 4a97I-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 5 GLU A  77
GLU A 131
PHE A 133
TYR A 175
HIS A 177
 None
 0.88A 4a97J-4yeuA:
29.6		 4a97J-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_A_377A401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 5 GLU A  77
GLU A 131
TYR A 175
PHE A 188
 None
 0.58A 4twdA-4yeuA:
29.5
4twdE-4yeuA:
29.6		 4twdA-4yeuA:
71.25
4twdE-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 5 GLU A  77
GLU A 131
TYR A 175
PHE A 188
 None
 0.62A 4twdA-4yeuA:
29.5
4twdB-4yeuA:
29.3		 4twdA-4yeuA:
71.25
4twdB-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 6 GLU A 131
TYR A 175
LEU A 178
PHE A 188
 None
 0.55A 4twdB-4yeuA:
29.3
4twdC-4yeuA:
29.2		 4twdB-4yeuA:
71.25
4twdC-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 6 GLU A 131
TYR A 175
LEU A 178
PHE A 188
 None
 0.60A 4twdD-4yeuA:
29.5
4twdE-4yeuA:
29.6		 4twdD-4yeuA:
71.25
4twdE-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 7 GLU A  77
GLU A 131
TYR A 175
LEU A 178
PHE A 188
 None
 0.63A 4twdF-4yeuA:
29.6
4twdJ-4yeuA:
29.4		 4twdF-4yeuA:
71.25
4twdJ-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 6 GLU A 131
TYR A 175
LEU A 178
PHE A 188
 None
 0.52A 4twdF-4yeuA:
29.6
4twdG-4yeuA:
29.6		 4twdF-4yeuA:
71.25
4twdG-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 6 GLU A  77
GLU A 131
TYR A 175
PHE A 188
 None
 0.59A 4twdG-4yeuA:
29.6
4twdH-4yeuA:
29.5		 4twdG-4yeuA:
71.25
4twdH-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_H_377H402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 5 GLU A  77
GLU A 131
TYR A 175
PHE A 188
 None
 0.64A 4twdH-4yeuA:
29.5
4twdI-4yeuA:
29.5		 4twdH-4yeuA:
71.25
4twdI-4yeuA:
71.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 6 GLU A 131
TYR A 175
LEU A 178
PHE A 188
 None
 0.61A 4twdI-4yeuA:
29.5
4twdJ-4yeuA:
29.4		 4twdI-4yeuA:
71.25
4twdJ-4yeuA:
71.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 6 LEU A 130
LEU A 128
GLU A 129
ASN A  80
 None
 0.92A 4ww7A-4yeuA:
undetectable		 4ww7A-4yeuA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 7 LYS A 255
LEU A 253
ILE A 269
LEU A 213
 None
 1.06A 5fxtA-4yeuA:
undetectable		 5fxtA-4yeuA:
23.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 11 ILE A  20
ILE A  23
PHE A 126
ASP A 158
TRP A 160
ALA A 197
 None
 0.68A 5lg3A-4yeuA:
29.3		 5lg3A-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 11 ILE A  20
ILE A  23
PHE A 126
TRP A 160
ILE A 162
ALA A 197
 None
 0.70A 5lg3A-4yeuA:
29.3		 5lg3A-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 11 ILE A  20
ILE A  23
PHE A 126
VAL A 147
TRP A 160
ALA A 197
 None
 0.66A 5lg3A-4yeuA:
29.3		 5lg3A-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 11 ILE A  23
PHE A 126
THR A 149
TRP A 160
ILE A 162
 None
 0.91A 5lg3A-4yeuA:
29.3		 5lg3A-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A  23
PHE A 126
THR A 149
ASP A 158
TRP A 160
 None
 1.33A 5lg3B-4yeuA:
29.4		 5lg3B-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A  23
PHE A 126
THR A 149
TRP A 160
ILE A 162
 None
 0.94A 5lg3B-4yeuA:
29.4		 5lg3B-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A  23
PHE A 126
VAL A 147
THR A 149
TRP A 160
 None
 1.25A 5lg3B-4yeuA:
29.4		 5lg3B-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A  23
PHE A 126
THR A 149
TRP A 160
ILE A 162
 None
 0.87A 5lg3C-4yeuA:
29.3		 5lg3C-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A  23
PHE A 126
THR A 149
ASP A 158
TRP A 160
 None
 1.28A 5lg3D-4yeuA:
29.4		 5lg3D-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A  23
PHE A 126
VAL A 147
THR A 149
TRP A 160
 None
 1.25A 5lg3D-4yeuA:
29.4		 5lg3D-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 12 ILE A  20
ILE A  23
PHE A 126
ASN A 154
ILE A 162
ALA A 197
 None
 0.81A 5lg3E-4yeuA:
29.5		 5lg3E-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 12 ILE A  20
ILE A  23
PHE A 126
VAL A 147
ASN A 154
ASP A 158
ALA A 197
 None
 1.06A 5lg3E-4yeuA:
29.5		 5lg3E-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
TRP A 160
ILE A 162
 None
 0.74A 5lg3F-4yeuA:
29.4		 5lg3F-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 10 ILE A  20
ILE A  23
PHE A 126
VAL A 147
ASP A 158
TRP A 160
 None
 0.65A 5lg3F-4yeuA:
29.4		 5lg3F-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  23
PHE A 126
THR A 149
TRP A 160
ILE A 162
 None
 0.89A 5lg3F-4yeuA:
29.4		 5lg3F-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
ASP A 158
TRP A 160
 None
 0.50A 5lg3G-4yeuA:
29.4		 5lg3G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
TRP A 160
ILE A 162
 None
 0.70A 5lg3G-4yeuA:
29.4		 5lg3G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
VAL A 147
TRP A 160
 None
 0.56A 5lg3G-4yeuA:
29.4		 5lg3G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  23
PHE A 126
THR A 149
ASP A 158
TRP A 160
 None
 1.28A 5lg3G-4yeuA:
29.4		 5lg3G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  23
PHE A 126
THR A 149
TRP A 160
ILE A 162
 None
 0.88A 5lg3G-4yeuA:
29.4		 5lg3G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  23
PHE A 126
VAL A 147
THR A 149
TRP A 160
 None
 1.22A 5lg3G-4yeuA:
29.4		 5lg3G-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
ASP A 158
TRP A 160
 None
 0.54A 5lg3H-4yeuA:
29.4		 5lg3H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
TRP A 160
ILE A 162
 None
 0.75A 5lg3H-4yeuA:
29.4		 5lg3H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  20
ILE A  23
PHE A 126
VAL A 147
TRP A 160
 None
 0.55A 5lg3H-4yeuA:
29.4		 5lg3H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  23
PHE A 126
THR A 149
TRP A 160
ILE A 162
 None
 0.89A 5lg3H-4yeuA:
29.4		 5lg3H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A  23
PHE A 126
VAL A 147
THR A 149
TRP A 160
 None
 1.22A 5lg3H-4yeuA:
29.4		 5lg3H-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 9 ILE A  23
PHE A 126
ASP A 158
TRP A 160
 None
 0.52A 5lg3I-4yeuA:
29.4		 5lg3I-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 9 ILE A  23
PHE A 126
VAL A 147
TRP A 160
 None
 0.64A 5lg3I-4yeuA:
29.4		 5lg3I-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 12 ILE A  20
ILE A  23
PHE A 126
ASN A 154
TRP A 160
ILE A 162
 None
 0.77A 5lg3J-4yeuA:
29.5		 5lg3J-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 12 ILE A  20
ILE A  23
PHE A 126
VAL A 147
ASN A 154
ASP A 158
TRP A 160
 None
 1.12A 5lg3J-4yeuA:
29.5		 5lg3J-4yeuA:
71.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 12 ILE A  23
PHE A 126
THR A 149
ASN A 154
TRP A 160
ILE A 162
 None
 0.95A 5lg3J-4yeuA:
29.5		 5lg3J-4yeuA:
71.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 PRO A 120
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
 None
 0.78A 5murB-4yeuA:
20.1		 5murB-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 7 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
 None
 0.78A 5murB-4yeuA:
20.1		 5murB-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		8 / 10 PRO A 120
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
ILE A 266
ILE A 269
 None
 0.70A 5murE-4yeuA:
20.1		 5murE-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		8 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
ILE A 265
ILE A 266
ILE A 269
 None
 0.71A 5murE-4yeuA:
20.1		 5murE-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 ILE A 208
ILE A 209
TYR A 261
THR A 262
ILE A 265
 None
 0.49A 5mvnB-4yeuA:
19.7		 5mvnB-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 TYR A 204
ILE A 208
ILE A 209
THR A 262
ILE A 265
 None
 0.83A 5mvnB-4yeuA:
19.7		 5mvnB-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 ILE A 208
ILE A 209
TYR A 261
THR A 262
ILE A 265
 None
 0.45A 5mvnD-4yeuA:
19.8		 5mvnD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 PRO A 120
ILE A 208
ILE A 209
TYR A 261
THR A 262
 None
 0.89A 5mvnD-4yeuA:
19.8		 5mvnD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
THR A 262
ILE A 265
 None
 0.80A 5mvnD-4yeuA:
19.8		 5mvnD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 10 PRO A 120
ILE A 208
ILE A 209
MET A 212
TYR A 261
THR A 262
ILE A 265
 None
 0.84A 5mzrA-4yeuA:
19.7		 5mzrA-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
 None
 0.93A 5mzrA-4yeuA:
19.7		 5mzrA-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
VAL A 249
 None
 1.16A 5mzrA-4yeuA:
19.7		 5mzrA-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		7 / 10 PRO A 120
ILE A 208
ILE A 209
MET A 212
TYR A 261
THR A 262
ILE A 265
 None
 0.81A 5mzrC-4yeuA:
19.7		 5mzrC-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
 None
 0.92A 5mzrC-4yeuA:
19.7		 5mzrC-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 10 TYR A 204
ILE A 208
ILE A 209
MET A 212
VAL A 249
 None
 1.15A 5mzrC-4yeuA:
19.7		 5mzrC-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 9 ILE A 208
ILE A 209
MET A 212
TYR A 261
THR A 262
ILE A 265
 None
 0.59A 5mzrD-4yeuA:
19.8		 5mzrD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		6 / 9 PRO A 120
ILE A 208
MET A 212
TYR A 261
THR A 262
ILE A 265
 None
 0.83A 5mzrD-4yeuA:
19.8		 5mzrD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 TYR A 204
ILE A 208
ILE A 209
MET A 212
THR A 262
 None
 0.89A 5mzrD-4yeuA:
19.8		 5mzrD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		5 / 9 TYR A 204
ILE A 208
ILE A 209
MET A 212
VAL A 249
 None
 1.15A 5mzrD-4yeuA:
19.8		 5mzrD-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 8 ILE A 208
TYR A 261
THR A 262
ILE A 265
 None
 0.55A 5mzrE-4yeuA:
19.7		 5mzrE-4yeuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 4yeu CYS-LOOP
LIGAND-GATED ION
CHANNEL,PROTON-GATED
ION CHANNEL
(Dickeya
chrysanthemi;
Gloeobacter
violaceus) 		4 / 8 PRO A 120
ILE A 208
THR A 262
ILE A 265
 None
 0.83A 5mzrE-4yeuA:
19.7		 5mzrE-4yeuA:
13.49