SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLU A 169
LEU A 115
ASP A 116
GLY A  22
 None
 0.88A 1n13H-4yf1A:
undetectable
1n13K-4yf1A:
undetectable		 1n13H-4yf1A:
17.80
1n13K-4yf1A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 7 LEU A 115
ASP A 116
GLY A  22
GLU A 169
 None
 0.88A 1n13G-4yf1A:
undetectable
1n13J-4yf1A:
undetectable		 1n13G-4yf1A:
13.90
1n13J-4yf1A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 8 GLU A 169
LEU A 115
ASP A 116
GLY A  22
 None
 0.86A 2qqdB-4yf1A:
undetectable
2qqdC-4yf1A:
undetectable		 2qqdB-4yf1A:
17.80
2qqdC-4yf1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		3 / 3 LYS A  84
GLU A  82
TRP A  88
 None
 1.03A 3v4tH-4yf1A:
undetectable		 3v4tH-4yf1A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 5 ASP A 116
LEU A 115
ARG A 172
THR A  21
 None
 1.19A 4p3qA-4yf1A:
undetectable		 4p3qA-4yf1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 6 ASP A 113
TYR A 170
HIS A  28
THR A  21
 None
 1.11A 4paeA-4yf1A:
undetectable		 4paeA-4yf1A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A  79
ALA A  78
HIS A  80
LEU A  76
 None
 1.35A 5dzkb-4yf1A:
undetectable
5dzkp-4yf1A:
undetectable		 5dzkb-4yf1A:
23.24
5dzkp-4yf1A:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A  79
ALA A  78
HIS A  80
LEU A  76
 None
 1.33A 5dzkc-4yf1A:
undetectable
5dzkq-4yf1A:
undetectable		 5dzkc-4yf1A:
23.24
5dzkq-4yf1A:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASP A  57
ARG A 138
ARG A  91
 None
 0.99A 5eajB-4yf1A:
undetectable		 5eajB-4yf1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4yf1 LMO0812 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ALA A  93
TYR A 146
GLU A  82
HIS A  94
 None
 1.17A 5ecnA-4yf1A:
undetectable		 5ecnA-4yf1A:
15.44