SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4yfv VIOF
(Providencia
alcalifaciens) 		4 / 5 ILE A  72
ILE A 155
ILE A 121
LEU A  47
 None
 0.94A 1zgyA-4yfvA:
undetectable		 1zgyA-4yfvA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4yfv VIOF
(Providencia
alcalifaciens) 		3 / 3 TYR A 151
GLU A 158
ASN A  92
 None
 0.93A 2y7hC-4yfvA:
undetectable		 2y7hC-4yfvA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ILE A  72
ASN A  98
LEU A 166
ILE A 169
LEU A  89
 None
 1.18A 3a50A-4yfvA:
undetectable		 3a50A-4yfvA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ILE A  72
ASN A  98
LEU A 166
ILE A 169
LEU A  89
 None
 1.25A 3a50E-4yfvA:
undetectable		 3a50E-4yfvA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWP_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ASN A 222
CYH A 195
ASN A 192
TYR A 224
PHE A 234
 None
 1.27A 3qwpA-4yfvA:
undetectable		 3qwpA-4yfvA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 4yfv VIOF
(Providencia
alcalifaciens) 		4 / 5 ILE A  72
ASN A 165
TYR A 134
ILE A  91
 None
 0.89A 4jtpA-4yfvA:
undetectable		 4jtpA-4yfvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 4yfv VIOF
(Providencia
alcalifaciens) 		4 / 4 ASP A 129
GLY A  96
PRO A  95
GLN A 107
 None
 1.36A 4oltA-4yfvA:
undetectable		 4oltA-4yfvA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCL_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ASN A 222
CYH A 195
ASN A 192
TYR A 224
PHE A 234
 None
 1.30A 5cclA-4yfvA:
undetectable		 5cclA-4yfvA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V37_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ASN A 222
CYH A 195
ASN A 192
TYR A 224
PHE A 234
 None
 1.28A 5v37A-4yfvA:
undetectable		 5v37A-4yfvA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXG_A_SAMA502_0
(SMYD3)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ASN A 222
CYH A 195
ASN A 192
TYR A 224
PHE A 234
 None
 1.26A 5xxgA-4yfvA:
undetectable		 5xxgA-4yfvA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXJ_A_SAMA505_0
(SMYD3)		 4yfv VIOF
(Providencia
alcalifaciens) 		5 / 12 ASN A 222
CYH A 195
ASN A 192
TYR A 224
PHE A 234
 None
 1.27A 5xxjA-4yfvA:
undetectable		 5xxjA-4yfvA:
19.35