SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ygt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.13A 1c9sN-4ygtA:
undetectable
1c9sO-4ygtA:
undetectable		 1c9sN-4ygtA:
20.62
1c9sO-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 11 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.13A 1c9sP-4ygtA:
undetectable
1c9sQ-4ygtA:
undetectable		 1c9sP-4ygtA:
20.62
1c9sQ-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 9 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.16A 1c9sQ-4ygtA:
undetectable
1c9sR-4ygtA:
undetectable		 1c9sQ-4ygtA:
20.62
1c9sR-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A  85
GLY A 110
ALA A  67
HIS A  81
ILE A 122
 None
 1.14A 1c9sL-4ygtA:
undetectable
1c9sV-4ygtA:
undetectable		 1c9sL-4ygtA:
20.62
1c9sV-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 9 GLY A  85
GLY A 110
ALA A  67
HIS A  81
ILE A 122
 None
 1.09A 1gtfD-4ygtA:
undetectable
1gtfE-4ygtA:
undetectable		 1gtfD-4ygtA:
20.62
1gtfE-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 11 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.14A 1gtfQ-4ygtA:
undetectable
1gtfR-4ygtA:
undetectable		 1gtfQ-4ygtA:
20.62
1gtfR-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 9 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.14A 1gtfR-4ygtA:
undetectable
1gtfS-4ygtA:
undetectable		 1gtfR-4ygtA:
20.62
1gtfS-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 11 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.13A 1gtfS-4ygtA:
undetectable
1gtfT-4ygtA:
undetectable		 1gtfS-4ygtA:
20.62
1gtfT-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.12A 1utdE-4ygtA:
undetectable
1utdF-4ygtA:
undetectable		 1utdE-4ygtA:
20.62
1utdF-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.13A 1utdH-4ygtA:
undetectable
1utdI-4ygtA:
undetectable		 1utdH-4ygtA:
20.62
1utdI-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A 110
ALA A  67
HIS A  81
ILE A 122
GLY A  85
 None
 1.15A 1utdU-4ygtA:
undetectable
1utdV-4ygtA:
undetectable		 1utdU-4ygtA:
20.62
1utdV-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		3 / 3 GLY A 126
ARG A 131
TYR A 124
 None
 0.85A 2opxA-4ygtA:
undetectable		 2opxA-4ygtA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		4 / 8 SER A 120
VAL A 176
HIS A 174
ARG A 123
 None
None
None
SO4  A 201 (-3.6A)
 1.15A 3b9lA-4ygtA:
undetectable		 3b9lA-4ygtA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		4 / 8 ARG A  96
ASP A 163
GLU A 172
ARG A 123
 SO4  A 201 (-3.9A)
None
None
SO4  A 201 (-3.6A)
 1.23A 4kr4C-4ygtA:
undetectable		 4kr4C-4ygtA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A  85
GLY A 110
ALA A  67
HIS A  81
ILE A 122
 None
 1.17A 5ef1A-4ygtA:
undetectable
5ef1B-4ygtA:
undetectable		 5ef1A-4ygtA:
20.62
5ef1B-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		5 / 10 GLY A  85
GLY A 110
ALA A  67
HIS A  81
ILE A 122
 None
 1.17A 5ef3A-4ygtA:
undetectable
5ef3B-4ygtA:
undetectable		 5ef3A-4ygtA:
20.62
5ef3B-4ygtA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4ygt UNCHARACTERIZED
PROTEIN YJGB
(Bacillus
subtilis) 		4 / 5 GLY A  61
THR A  57
GLN A  68
THR A  71
 None
 1.26A 5h5fA-4ygtA:
undetectable		 5h5fA-4ygtA:
21.43