SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		3 / 3 THR A  29
PRO A  58
PRO A  30
 None
 0.83A 2d55C-4yh7A:
undetectable		 2d55C-4yh7A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		4 / 7 PHE A  50
GLN A  40
LEU A 120
LEU A  94
 None
 0.83A 3bgdB-4yh7A:
undetectable		 3bgdB-4yh7A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		3 / 3 ARG A 181
ASP A  83
GLN A  53
 None
 0.83A 4azsA-4yh7A:
undetectable		 4azsA-4yh7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		3 / 3 SER A 176
ASP A 174
GLN A  53
 None
 0.92A 4oltA-4yh7A:
undetectable
4oltB-4yh7A:
undetectable		 4oltA-4yh7A:
16.11
4oltB-4yh7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		3 / 3 GLN A  53
SER A 176
ASP A 174
 None
 0.88A 4qwpA-4yh7A:
undetectable
4qwpB-4yh7A:
undetectable		 4qwpA-4yh7A:
16.24
4qwpB-4yh7A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		4 / 7 GLU A  80
SER A  87
ILE A  62
VAL A  63
 None
 1.05A 4tvtA-4yh7A:
undetectable		 4tvtA-4yh7A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		4 / 6 LEU A 592
LEU A 556
GLU A 555
ILE A 571
 None
 0.81A 4ww7A-4yh7A:
undetectable		 4ww7A-4yh7A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM7_A_ACTA603_0
(SALICYLATE-AMP
LIGASE)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		4 / 4 THR A  34
THR A  55
ALA A  54
ARG A  32
 None
 1.35A 5wm7A-4yh7A:
undetectable		 5wm7A-4yh7A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		3 / 3 LYS A 331
PRO A 330
LYS A 327
 None
 1.19A 5y9yA-4yh7A:
undetectable		 5y9yA-4yh7A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 4yh7 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE DELTA
(Mus
musculus) 		5 / 9 SER A 246
ALA A 320
VAL A 274
ALA A 311
VAL A 265
 None
 1.27A 6bklA-4yh7A:
undetectable
6bklB-4yh7A:
undetectable
6bklC-4yh7A:
undetectable
6bklD-4yh7A:
undetectable		 6bklA-4yh7A:
2.84
6bklB-4yh7A:
2.84
6bklC-4yh7A:
2.84
6bklD-4yh7A:
2.84