SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yhg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ALA A  34
VAL A  70
TRP A  88
 None
 0.84A 1jnoA-4yhgA:
undetectable		 1jnoA-4yhgA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ALA A  34
VAL A  70
TRP A  88
 None
 0.84A 1jnoB-4yhgA:
undetectable		 1jnoB-4yhgA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ALA A  34
VAL A  70
TRP A  88
 None
 0.93A 1magA-4yhgA:
undetectable		 1magA-4yhgA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ALA A  34
VAL A  70
TRP A  88
 None
 0.93A 1magB-4yhgA:
undetectable		 1magB-4yhgA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ALA A  34
VAL A  70
TRP A  88
 None
 0.85A 1ng8A-4yhgA:
undetectable		 1ng8A-4yhgA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ALA A  34
VAL A  70
TRP A  88
 None
 0.85A 1ng8B-4yhgA:
undetectable		 1ng8B-4yhgA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 ARG A 318
SER A 387
TYR A 389
 None
 0.79A 1x70A-4yhgA:
undetectable		 1x70A-4yhgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 LEU A  95
MET A  98
MET A  22
 None
 0.98A 2vavF-4yhgA:
undetectable		 2vavF-4yhgA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		4 / 6 GLY A 352
ARG A 318
ILE A 362
VAL A 353
 None
 1.08A 3kvvD-4yhgA:
undetectable		 3kvvD-4yhgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		4 / 6 GLY A 352
ARG A 318
ILE A 362
VAL A 353
 None
 1.09A 3kvvE-4yhgA:
undetectable		 3kvvE-4yhgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		4 / 6 GLY A 352
ARG A 318
ILE A 362
VAL A 353
 None
 1.09A 3kvvF-4yhgA:
undetectable		 3kvvF-4yhgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 GLY A 305
GLY A 258
LEU A 337
ASN A  27
PHE A 301
 None
 1.35A 3r24A-4yhgA:
undetectable		 3r24A-4yhgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 ALA A  99
LEU A  58
ASN A  56
ALA A  50
ILE A 354
 None
 1.13A 3ut5D-4yhgA:
undetectable		 3ut5D-4yhgA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		3 / 3 LEU A 128
MET A  73
ASP A  33
 None
 0.90A 3v5wA-4yhgA:
undetectable		 3v5wA-4yhgA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		4 / 6 GLN A 190
ASP A 129
GLU A 146
LEU A 194
 None
 1.24A 4ax8A-4yhgA:
undetectable		 4ax8A-4yhgA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		4 / 6 GLY A 352
ARG A 318
ILE A 362
VAL A 353
 None
 1.12A 4e1vF-4yhgA:
undetectable		 4e1vF-4yhgA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 ASP A 227
ASN A 225
ILE A 334
VAL A 219
ARG A 287
 None
 1.04A 4q5mA-4yhgA:
undetectable		 4q5mA-4yhgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		4 / 7 GLU A 278
GLY A 269
TYR A 320
GLY A 266
 None
 0.83A 4rdxA-4yhgA:
undetectable		 4rdxA-4yhgA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 9 VAL A  96
VAL A  92
ILE A 154
PHE A 167
LEU A 165
 None
 1.40A 5e4dA-4yhgA:
undetectable		 5e4dA-4yhgA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 ALA A  99
LEU A  58
ASN A  56
ALA A  50
ILE A 354
 None
 1.05A 5eypB-4yhgA:
undetectable		 5eypB-4yhgA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 ALA A  99
LEU A  58
ASN A  56
ALA A  50
ILE A 354
 None
 1.13A 5nm5B-4yhgA:
2.8		 5nm5B-4yhgA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 ARG A  67
GLU A 168
TYR A 251
ASN A 171
HIS A 111
 None
None
CT3  A 401 (-4.4A)
CT3  A 401 (-3.1A)
CT3  A 401 (-4.2A)
 1.49A 6b1eB-4yhgA:
undetectable		 6b1eB-4yhgA:
19.84