SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_P_CHDP4525_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE III)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	1v54N-4yipA: undetectable 1v54P-4yipA: undetectable	1v54N-4yipA: 18.18 1v54P-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXM_A_IMNA2001_1 (SERUM ALBUMIN)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 8	ALA A 115 PHE A 116 ALA A 120 ARG A 123	None	0.30A	2bxmA-4yipA: undetectable	2bxmA-4yipA: 16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	2dyrA-4yipA: undetectable 2dyrC-4yipA: undetectable	2dyrA-4yipA: 18.18 2dyrC-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	2dyrN-4yipA: undetectable 2dyrP-4yipA: undetectable	2dyrN-4yipA: 18.18 2dyrP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	2dysA-4yipA: undetectable 2dysC-4yipA: undetectable	2dysA-4yipA: 18.18 2dysC-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_P_CHDP304_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.47A	2dysN-4yipA: undetectable 2dysP-4yipA: undetectable	2dysN-4yipA: 18.18 2dysP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	2eijA-4yipA: undetectable 2eijC-4yipA: undetectable	2eijA-4yipA: 18.18 2eijC-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	2eijN-4yipA: 1.4 2eijP-4yipA: undetectable	2eijN-4yipA: 18.18 2eijP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	2eikN-4yipA: undetectable 2eikP-4yipA: undetectable	2eikN-4yipA: 18.18 2eikP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_A_CHDA525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.46A	2eimA-4yipA: undetectable 2eimC-4yipA: undetectable	2eimA-4yipA: 18.18 2eimC-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.48A	2einA-4yipA: undetectable 2einC-4yipA: undetectable	2einA-4yipA: 18.18 2einC-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V2G_A_BEZA1222_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.99A	2v2gA-4yipA: undetectable 2v2gB-4yipA: undetectable	2v2gA-4yipA: 24.30 2v2gB-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V2G_B_BEZB1220_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.96A	2v2gA-4yipA: undetectable 2v2gB-4yipA: undetectable	2v2gA-4yipA: 24.30 2v2gB-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V2G_C_BEZC1222_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 7	THR A 149 PRO A 150 SER A 152 GLU A 53 PRO A 157	None	1.36A	2v2gC-4yipA: undetectable 2v2gD-4yipA: undetectable	2v2gC-4yipA: 24.30 2v2gD-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V2G_D_BEZD1221_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.98A	2v2gC-4yipA: undetectable 2v2gD-4yipA: undetectable	2v2gC-4yipA: 24.30 2v2gD-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V32_A_BEZA1222_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 8	THR A 149 PRO A 150 SER A 152 GLU A 53 PRO A 157	None	1.32A	2v32A-4yipA: undetectable 2v32B-4yipA: undetectable	2v32A-4yipA: 24.30 2v32B-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V32_B_BEZB1220_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 8	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.95A	2v32A-4yipA: undetectable 2v32B-4yipA: undetectable	2v32A-4yipA: 24.30 2v32B-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V32_C_BEZC1222_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 8	THR A 149 PRO A 150 SER A 152 GLU A 53 PRO A 157	None	1.40A	2v32C-4yipA: undetectable 2v32D-4yipA: undetectable	2v32C-4yipA: 24.30 2v32D-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V32_D_BEZD1221_0 (PEROXIREDOXIN 6)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 8	THR A 149 PRO A 150 SER A 152 GLU A 53	None	1.00A	2v32C-4yipA: undetectable 2v32D-4yipA: undetectable	2v32C-4yipA: 24.30 2v32D-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_D_BEZD1222_0 (PEROXIREDOXIN 6.)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 8	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.98A	2v41C-4yipA: undetectable 2v41D-4yipA: undetectable	2v41C-4yipA: 24.30 2v41D-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_E_BEZE1222_0 (PEROXIREDOXIN 6.)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.99A	2v41E-4yipA: undetectable 2v41F-4yipA: undetectable	2v41E-4yipA: 24.30 2v41F-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_F_BEZF1222_0 (PEROXIREDOXIN 6.)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	THR A 149 PRO A 150 SER A 152 GLU A 53	None	1.03A	2v41E-4yipA: undetectable 2v41F-4yipA: undetectable	2v41E-4yipA: 24.30 2v41F-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_G_BEZG1222_0 (PEROXIREDOXIN 6.)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 8	THR A 149 PRO A 150 SER A 152 GLU A 53	None	0.86A	2v41G-4yipA: undetectable 2v41H-4yipA: undetectable	2v41G-4yipA: 24.30 2v41H-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_H_BEZH1222_0 (PEROXIREDOXIN 6.)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 8	PRO A 157 THR A 149 PRO A 150 SER A 152 GLU A 53	None	1.39A	2v41G-4yipA: undetectable 2v41H-4yipA: undetectable	2v41G-4yipA: 24.30 2v41H-4yipA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	2zxwA-4yipA: undetectable 2zxwC-4yipA: undetectable	2zxwA-4yipA: 18.18 2zxwC-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	2zxwN-4yipA: undetectable 2zxwP-4yipA: undetectable	2zxwN-4yipA: 18.18 2zxwP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	3abkN-4yipA: undetectable 3abkP-4yipA: undetectable	3abkN-4yipA: 18.18 3abkP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	3abmN-4yipA: undetectable 3abmP-4yipA: undetectable	3abmN-4yipA: 18.18 3abmP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	3ag2N-4yipA: undetectable 3ag2P-4yipA: undetectable	3ag2N-4yipA: 18.18 3ag2P-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	3ag3A-4yipA: undetectable 3ag3C-4yipA: undetectable	3ag3A-4yipA: 18.18 3ag3C-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	3ag4A-4yipA: undetectable 3ag4C-4yipA: undetectable	3ag4A-4yipA: 18.18 3ag4C-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_B_9PLB1_1 (CYTOCHROME P450 2A13)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	PHE A 109 PHE A 112 ALA A 114 THR A 117	None	1.04A	3t3sB-4yipA: undetectable	3t3sB-4yipA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_F_9PLF1_1 (CYTOCHROME P450 2A13)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 8	PHE A 109 PHE A 184 PHE A 112 ALA A 114 THR A 117	None	1.43A	3t3sF-4yipA: undetectable	3t3sF-4yipA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_F_9PLF1_1 (CYTOCHROME P450 2A13)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 8	PHE A 109 PHE A 184 PHE A 112 ALA A 115 THR A 117	None	1.29A	3t3sF-4yipA: undetectable	3t3sF-4yipA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JTR_A_IBPA401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 8	VAL A 94 TRP A 189 LEU A 139 LEU A 131	None	1.08A	4jtrA-4yipA: undetectable	4jtrA-4yipA: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 7	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.49A	5b1bN-4yipA: undetectable 5b1bP-4yipA: undetectable	5b1bN-4yipA: 18.18 5b1bP-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMX_B_RBFB202_1 (GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 10	LEU A 86 TRP A 130 GLY A 75 HIS A 77 TRP A 128	None	1.46A	5umxA-4yipA: 0.1 5umxB-4yipA: 0.0	5umxA-4yipA: 18.68 5umxB-4yipA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	4 / 6	HIS A 26 ASP A 12 TYR A 9 HIS A 30	FE A 301 (-3.3A) None None None	1.50A	5x19N-4yipA: 1.5 5x19P-4yipA: undetectable	5x19N-4yipA: 18.18 5x19P-4yipA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRY_A_H8DA2001_0 (5HT2B RECEPTOR, BRIL CHIMERA)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	5 / 11	VAL A 98 THR A 95 VAL A 141 LEU A 131 PHE A 109	None	1.24A	6dryA-4yipA: undetectable	6dryA-4yipA: 20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F7L_B_ACTB505_0 (AMINE OXIDASE LKCE)	4yip	SUPEROXIDE DISMUTASE [MN/FE] (Streptococcus mutans)	3 / 3	HIS A 80 ASN A 79 LEU A 78	FE A 301 (-3.4A) None None	0.90A	6f7lB-4yipA: undetectable	6f7lB-4yipA: 18.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1V54_P_CHDP4525_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE III","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","1v54N-4yipA:undetectable;1v54P-4yipA:undetectable","1v54N-4yipA:18.18;1v54P-4yipA:19.06"],["2BXM_A_IMNA2001_1","SERUM ALBUMIN","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"ALA A 115;PHE A 116;ALA A 120;ARG A 123","None","0.30A","2bxmA-4yipA:undetectable","2bxmA-4yipA:16.91"],["2DYR_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","2dyrA-4yipA:undetectable;2dyrC-4yipA:undetectable","2dyrA-4yipA:18.18;2dyrC-4yipA:19.06"],["2DYR_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","2dyrN-4yipA:undetectable;2dyrP-4yipA:undetectable","2dyrN-4yipA:18.18;2dyrP-4yipA:19.06"],["2DYS_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","2dysA-4yipA:undetectable;2dysC-4yipA:undetectable","2dysA-4yipA:18.18;2dysC-4yipA:19.06"],["2DYS_P_CHDP304_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.47A","2dysN-4yipA:undetectable;2dysP-4yipA:undetectable","2dysN-4yipA:18.18;2dysP-4yipA:19.06"],["2EIJ_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","2eijA-4yipA:undetectable;2eijC-4yipA:undetectable","2eijA-4yipA:18.18;2eijC-4yipA:19.06"],["2EIJ_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","2eijN-4yipA:1.4;2eijP-4yipA:undetectable","2eijN-4yipA:18.18;2eijP-4yipA:19.06"],["2EIK_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","2eikN-4yipA:undetectable;2eikP-4yipA:undetectable","2eikN-4yipA:18.18;2eikP-4yipA:19.06"],["2EIM_A_CHDA525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.46A","2eimA-4yipA:undetectable;2eimC-4yipA:undetectable","2eimA-4yipA:18.18;2eimC-4yipA:19.06"],["2EIN_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.48A","2einA-4yipA:undetectable;2einC-4yipA:undetectable","2einA-4yipA:18.18;2einC-4yipA:19.06"],["2V2G_A_BEZA1222_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.99A","2v2gA-4yipA:undetectable;2v2gB-4yipA:undetectable","2v2gA-4yipA:24.30;2v2gB-4yipA:24.30"],["2V2G_B_BEZB1220_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.96A","2v2gA-4yipA:undetectable;2v2gB-4yipA:undetectable","2v2gA-4yipA:24.30;2v2gB-4yipA:24.30"],["2V2G_C_BEZC1222_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"THR A 149;PRO A 150;SER A 152;GLU A  53;PRO A 157","None","1.36A","2v2gC-4yipA:undetectable;2v2gD-4yipA:undetectable","2v2gC-4yipA:24.30;2v2gD-4yipA:24.30"],["2V2G_D_BEZD1221_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.98A","2v2gC-4yipA:undetectable;2v2gD-4yipA:undetectable","2v2gC-4yipA:24.30;2v2gD-4yipA:24.30"],["2V32_A_BEZA1222_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"THR A 149;PRO A 150;SER A 152;GLU A  53;PRO A 157","None","1.32A","2v32A-4yipA:undetectable;2v32B-4yipA:undetectable","2v32A-4yipA:24.30;2v32B-4yipA:24.30"],["2V32_B_BEZB1220_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.95A","2v32A-4yipA:undetectable;2v32B-4yipA:undetectable","2v32A-4yipA:24.30;2v32B-4yipA:24.30"],["2V32_C_BEZC1222_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"THR A 149;PRO A 150;SER A 152;GLU A  53;PRO A 157","None","1.40A","2v32C-4yipA:undetectable;2v32D-4yipA:undetectable","2v32C-4yipA:24.30;2v32D-4yipA:24.30"],["2V32_D_BEZD1221_0","PEROXIREDOXIN 6","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","1.00A","2v32C-4yipA:undetectable;2v32D-4yipA:undetectable","2v32C-4yipA:24.30;2v32D-4yipA:24.30"],["2V41_D_BEZD1222_0","PEROXIREDOXIN 6.","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.98A","2v41C-4yipA:undetectable;2v41D-4yipA:undetectable","2v41C-4yipA:24.30;2v41D-4yipA:24.30"],["2V41_E_BEZE1222_0","PEROXIREDOXIN 6.","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.99A","2v41E-4yipA:undetectable;2v41F-4yipA:undetectable","2v41E-4yipA:24.30;2v41F-4yipA:24.30"],["2V41_F_BEZF1222_0","PEROXIREDOXIN 6.","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","1.03A","2v41E-4yipA:undetectable;2v41F-4yipA:undetectable","2v41E-4yipA:24.30;2v41F-4yipA:24.30"],["2V41_G_BEZG1222_0","PEROXIREDOXIN 6.","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"THR A 149;PRO A 150;SER A 152;GLU A  53","None","0.86A","2v41G-4yipA:undetectable;2v41H-4yipA:undetectable","2v41G-4yipA:24.30;2v41H-4yipA:24.30"],["2V41_H_BEZH1222_0","PEROXIREDOXIN 6.","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"PRO A 157;THR A 149;PRO A 150;SER A 152;GLU A  53","None","1.39A","2v41G-4yipA:undetectable;2v41H-4yipA:undetectable","2v41G-4yipA:24.30;2v41H-4yipA:24.30"],["2ZXW_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","2zxwA-4yipA:undetectable;2zxwC-4yipA:undetectable","2zxwA-4yipA:18.18;2zxwC-4yipA:19.06"],["2ZXW_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","2zxwN-4yipA:undetectable;2zxwP-4yipA:undetectable","2zxwN-4yipA:18.18;2zxwP-4yipA:19.06"],["3ABK_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","3abkN-4yipA:undetectable;3abkP-4yipA:undetectable","3abkN-4yipA:18.18;3abkP-4yipA:19.06"],["3ABM_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","3abmN-4yipA:undetectable;3abmP-4yipA:undetectable","3abmN-4yipA:18.18;3abmP-4yipA:19.06"],["3AG2_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","3ag2N-4yipA:undetectable;3ag2P-4yipA:undetectable","3ag2N-4yipA:18.18;3ag2P-4yipA:19.06"],["3AG3_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","3ag3A-4yipA:undetectable;3ag3C-4yipA:undetectable","3ag3A-4yipA:18.18;3ag3C-4yipA:19.06"],["3AG4_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","3ag4A-4yipA:undetectable;3ag4C-4yipA:undetectable","3ag4A-4yipA:18.18;3ag4C-4yipA:19.06"],["3T3S_B_9PLB1_1","CYTOCHROME P450 2A13","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"PHE A 109;PHE A 112;ALA A 114;THR A 117","None","1.04A","3t3sB-4yipA:undetectable","3t3sB-4yipA:19.29"],["3T3S_F_9PLF1_1","CYTOCHROME P450 2A13","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"PHE A 109;PHE A 184;PHE A 112;ALA A 114;THR A 117","None","1.43A","3t3sF-4yipA:undetectable","3t3sF-4yipA:19.29"],["3T3S_F_9PLF1_1","CYTOCHROME P450 2A13","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"PHE A 109;PHE A 184;PHE A 112;ALA A 115;THR A 117","None","1.29A","3t3sF-4yipA:undetectable","3t3sF-4yipA:19.29"],["4JTR_A_IBPA401_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"VAL A  94;TRP A 189;LEU A 139;LEU A 131","None","1.08A","4jtrA-4yipA:undetectable","4jtrA-4yipA:23.26"],["5B1B_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.49A","5b1bN-4yipA:undetectable;5b1bP-4yipA:undetectable","5b1bN-4yipA:18.18;5b1bP-4yipA:19.06"],["5UMX_B_RBFB202_1","GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE;GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"LEU A  86;TRP A 130;GLY A  75;HIS A  77;TRP A 128","None","1.46A","5umxA-4yipA:0.1;5umxB-4yipA:0.0","5umxA-4yipA:18.68;5umxB-4yipA:18.68"],["5X19_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",4,"HIS A  26;ASP A  12;TYR A   9;HIS A  30"," FE A 301 (-3.3A);None;None;None","1.50A","5x19N-4yipA:1.5;5x19P-4yipA:undetectable","5x19N-4yipA:18.18;5x19P-4yipA:19.06"],["6DRY_A_H8DA2001_0","5HT2B RECEPTOR, BRIL CHIMERA","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",5,"VAL A  98;THR A  95;VAL A 141;LEU A 131;PHE A 109","None","1.24A","6dryA-4yipA:undetectable","6dryA-4yipA:20.10"],["6F7L_B_ACTB505_0","AMINE OXIDASE LKCE","4yip","SUPEROXIDE DISMUTASE [MN\/FE]","Streptococcus mutans",3,"HIS A  80;ASN A  79;LEU A  78"," FE A 301 (-3.4A);None;None","0.90A","6f7lB-4yipA:undetectable","6f7lB-4yipA:18.14"]]