SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		6 / 12 THR A 142
GLY A 162
ILE A 188
ALA A 167
GLY A 166
ALA A 168
 None
 1.25A 1bx4A-4yjiA:
undetectable		 1bx4A-4yjiA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 4 ILE A 428
MET A 325
VAL A 381
GLY A 185
 None
None
None
TYL  A 502 (-3.6A)
 1.02A 1e06B-4yjiA:
undetectable		 1e06B-4yjiA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 ILE A 360
TYR A 136
PHE A 138
PHE A  87
 None
 0.99A 1e71M-4yjiA:
undetectable		 1e71M-4yjiA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 ILE A 360
TYR A 136
PHE A 138
PHE A  87
 None
 0.99A 1e72M-4yjiA:
undetectable		 1e72M-4yjiA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 6 ILE A 360
TYR A 136
PHE A 138
PHE A  87
 None
 0.98A 1e73M-4yjiA:
undetectable		 1e73M-4yjiA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 9 GLY A 162
ALA A 167
THR A 150
THR A 142
THR A 195
 None
 1.11A 1gtnR-4yjiA:
undetectable
1gtnS-4yjiA:
undetectable		 1gtnR-4yjiA:
9.31
1gtnS-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 LEU A 309
LEU A 435
TYR A 434
LEU A 377
 None
 1.19A 1hk2A-4yjiA:
undetectable		 1hk2A-4yjiA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 GLY A 129
TYR A  53
ILE A  38
GLU A  39
 None
 0.83A 1mrjA-4yjiA:
undetectable		 1mrjA-4yjiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 PHE A 477
ALA A 293
ILE A 460
ILE A 271
 None
 0.97A 1oniD-4yjiA:
undetectable
1oniF-4yjiA:
undetectable		 1oniD-4yjiA:
14.98
1oniF-4yjiA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 6 GLY A 225
ILE A 227
GLY A 180
TYR A 116
 None
 0.83A 1usqB-4yjiA:
undetectable		 1usqB-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 6 GLY A 225
ILE A 227
GLY A 180
TYR A 116
 None
 0.81A 1usqC-4yjiA:
undetectable		 1usqC-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 6 GLY A 225
ILE A 227
GLY A 180
TYR A 116
 None
 0.82A 1usqD-4yjiA:
undetectable		 1usqD-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 6 GLY A 225
PRO A 226
ILE A 227
GLY A 180
TYR A 116
 None
 1.36A 1usqE-4yjiA:
undetectable		 1usqE-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 ILE A 460
ASP A 393
PHE A 389
 None
 0.59A 1uwjB-4yjiA:
undetectable		 1uwjB-4yjiA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 GLY A 181
GLY A 180
ASP A 183
PHE A  87
SER A 164
 None
None
TYL  A 502 ( 4.8A)
None
None
 1.17A 1wg8B-4yjiA:
undetectable		 1wg8B-4yjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 6 GLY A 225
PRO A 226
ILE A 227
GLY A 180
TYR A 116
 None
 1.41A 2jkjB-4yjiA:
undetectable		 2jkjB-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 6 GLY A 225
PRO A 226
ILE A 227
GLY A 180
TYR A 116
 None
 1.41A 2jkjC-4yjiA:
undetectable		 2jkjC-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 GLY A 225
PRO A 226
THR A  81
GLY A 180
 None
 0.77A 2jklF-4yjiA:
undetectable		 2jklF-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 ALA A 168
THR A 197
ALA A  13
LEU A 127
TYR A 116
 None
 1.21A 2nyrA-4yjiA:
undetectable		 2nyrA-4yjiA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 9 THR A  34
VAL A 176
GLY A  78
GLU A  15
ILE A  16
 None
 1.45A 2w98A-4yjiA:
undetectable		 2w98A-4yjiA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 PRO A 447
ALA A 448
ALA A 167
ALA A 169
MET A 403
 None
 1.27A 2x2nB-4yjiA:
undetectable		 2x2nB-4yjiA:
23.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 GLY A 129
ALA A  56
VAL A  31
ILE A  38
 None
 0.74A 3a2qA-4yjiA:
47.9		 3a2qA-4yjiA:
31.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 LEU A 454
ALA A 456
ILE A 451
ILE A 419
GLN A 283
 None
 1.07A 3b2rA-4yjiA:
undetectable		 3b2rA-4yjiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 11 LEU A 454
ALA A 456
ILE A 451
ILE A 419
GLN A 283
 None
 1.05A 3b2rB-4yjiA:
undetectable		 3b2rB-4yjiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		6 / 10 LEU A 262
ASP A 467
VAL A 470
GLY A 199
ALA A 475
ILE A 471
 None
 1.19A 3ekpB-4yjiA:
undetectable		 3ekpB-4yjiA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 9 LEU A 262
VAL A 470
GLY A 199
ALA A 475
ILE A 471
 None
 0.96A 3el0B-4yjiA:
undetectable		 3el0B-4yjiA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 11 ARG A 232
VAL A 207
PRO A 208
PRO A 202
ILE A 471
 None
 1.50A 3ganA-4yjiA:
undetectable		 3ganA-4yjiA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 GLY A 140
PRO A 191
ALA A 168
ALA A 169
THR A 131
 TYL  A 502 ( 4.9A)
None
None
None
None
 1.02A 3mteA-4yjiA:
undetectable		 3mteA-4yjiA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 GLU A  32
SER A  33
VAL A  31
VAL A   8
 None
 1.22A 3n61A-4yjiA:
undetectable
3n61B-4yjiA:
undetectable		 3n61A-4yjiA:
20.60
3n61B-4yjiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 LEU A  82
GLY A 180
GLY A 181
ILE A 175
VAL A 178
 None
 1.02A 3nk7A-4yjiA:
undetectable		 3nk7A-4yjiA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 GLU A  32
SER A  33
VAL A  31
VAL A   8
 None
 1.15A 3nlrA-4yjiA:
undetectable
3nlrB-4yjiA:
undetectable		 3nlrA-4yjiA:
20.60
3nlrB-4yjiA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		6 / 10 LEU A 256
ALA A 466
ASP A 463
VAL A 470
GLY A 440
ILE A 204
 None
 1.21A 3ogqA-4yjiA:
undetectable		 3ogqA-4yjiA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 GLY A 140
PRO A 191
ALA A 168
ALA A 169
THR A 131
 TYL  A 502 ( 4.9A)
None
None
None
None
 1.05A 3p2kA-4yjiA:
undetectable		 3p2kA-4yjiA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 5 ILE A  16
PRO A  80
SER A  26
GLY A  78
 None
 1.11A 3tkdB-4yjiA:
2.4		 3tkdB-4yjiA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 5 ILE A  16
PRO A  80
SER A  26
GLY A  78
 None
 1.09A 3tkdA-4yjiA:
2.6		 3tkdA-4yjiA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 7 ARG A 493
ALA A 491
TRP A  10
GLY A 174
 None
 0.87A 3v4tH-4yjiA:
undetectable		 3v4tH-4yjiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 TYR A 198
ILE A 460
VAL A 231
VAL A 207
LEU A 256
 None
 1.10A 3w68B-4yjiA:
undetectable		 3w68B-4yjiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 6 THR A 150
ASN A  46
GLY A  44
ILE A 175
 None
 0.92A 3w9tF-4yjiA:
undetectable		 3w9tF-4yjiA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 ASP A 245
ARG A 212
LYS A 210
 None
 1.21A 3wipG-4yjiA:
undetectable		 3wipG-4yjiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 TYR A 221
ARG A 464
SER A 439
 None
 1.02A 4dr2I-4yjiA:
undetectable
4dr2J-4yjiA:
undetectable		 4dr2I-4yjiA:
14.20
4dr2J-4yjiA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 ARG A 139
TRP A 430
GLY A 415
 None
 0.72A 4e7cA-4yjiA:
undetectable		 4e7cA-4yjiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 ARG A 493
TRP A  10
GLY A 174
 None
 1.01A 4e7cA-4yjiA:
undetectable		 4e7cA-4yjiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 TYR A 221
ARG A 464
SER A 439
 None
 1.04A 4lf7I-4yjiA:
undetectable
4lf7J-4yjiA:
undetectable		 4lf7I-4yjiA:
14.20
4lf7J-4yjiA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 TYR A 221
ARG A 464
SER A 439
 None
 1.04A 4lf8I-4yjiA:
undetectable
4lf8J-4yjiA:
undetectable		 4lf8I-4yjiA:
14.20
4lf8J-4yjiA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 ASP A 183
GLY A 184
GLY A 185
LEU A 435
GLY A 162
 TYL  A 502 ( 4.8A)
TYL  A 502 (-3.4A)
TYL  A 502 (-3.6A)
None
None
 0.94A 4n09C-4yjiA:
undetectable		 4n09C-4yjiA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		3 / 3 MET A 432
GLN A 317
TYR A 313
 None
 1.03A 4udcA-4yjiA:
undetectable		 4udcA-4yjiA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 9 PRO A 177
LEU A 128
ILE A 175
VAL A  31
THR A  34
 None
 1.22A 4x3mB-4yjiA:
undetectable		 4x3mB-4yjiA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 MET A  83
GLY A 166
SER A 163
ALA A 160
ALA A 168
 None
None
TYL  A 502 (-3.4A)
None
None
 1.08A 4ymgA-4yjiA:
undetectable		 4ymgA-4yjiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 MET A  83
GLY A 166
SER A 163
ALA A 160
ALA A 168
 None
None
TYL  A 502 (-3.4A)
None
None
 1.14A 4ymgB-4yjiA:
undetectable		 4ymgB-4yjiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 GLY A  44
PRO A 153
ARG A 151
ALA A 172
LEU A 170
 None
 1.09A 5bw4B-4yjiA:
undetectable		 5bw4B-4yjiA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 THR A 195
GLY A 162
ALA A 167
THR A 150
 None
 0.94A 5eevL-4yjiA:
undetectable
5eevV-4yjiA:
undetectable		 5eevL-4yjiA:
9.31
5eevV-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 THR A 195
GLY A 162
ALA A 167
THR A 150
 None
 0.94A 5eewL-4yjiA:
undetectable
5eewV-4yjiA:
undetectable		 5eewL-4yjiA:
9.31
5eewV-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 10 GLY A 162
ALA A 167
THR A 150
THR A 142
THR A 195
 None
 1.09A 5eezS-4yjiA:
undetectable
5eezT-4yjiA:
undetectable		 5eezS-4yjiA:
9.31
5eezT-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 10 GLY A 162
ALA A 167
THR A 150
THR A 142
THR A 195
 None
 1.09A 5ef0S-4yjiA:
undetectable
5ef0T-4yjiA:
undetectable		 5ef0S-4yjiA:
9.31
5ef0T-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 10 GLY A 162
ALA A 167
THR A 150
THR A 142
THR A 195
 None
 1.09A 5ef1S-4yjiA:
undetectable
5ef1T-4yjiA:
undetectable		 5ef1S-4yjiA:
9.31
5ef1T-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 10 GLY A 162
ALA A 167
THR A 150
THR A 142
THR A 195
 None
 1.09A 5ef2S-4yjiA:
undetectable
5ef2T-4yjiA:
undetectable		 5ef2S-4yjiA:
9.31
5ef2T-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 THR A 195
GLY A 162
ALA A 167
THR A 150
 None
 0.93A 5ef3L-4yjiA:
undetectable
5ef3V-4yjiA:
undetectable		 5ef3L-4yjiA:
9.31
5ef3V-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 10 GLY A 162
ALA A 167
THR A 150
THR A 142
THR A 195
 None
 1.09A 5ef3S-4yjiA:
undetectable
5ef3T-4yjiA:
undetectable		 5ef3S-4yjiA:
9.31
5ef3T-4yjiA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 8 GLY A 219
TRP A 322
ASP A 183
ARG A 189
 None
None
TYL  A 502 ( 4.8A)
None
 1.06A 5gqbA-4yjiA:
undetectable		 5gqbA-4yjiA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		6 / 12 THR A 142
GLY A 162
ALA A 167
GLY A 166
ALA A 168
ILE A 227
 None
 1.14A 5kb6A-4yjiA:
undetectable		 5kb6A-4yjiA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		6 / 12 THR A 142
GLY A 162
ILE A 188
ALA A 167
GLY A 166
ALA A 168
 None
 1.26A 5kb6A-4yjiA:
undetectable		 5kb6A-4yjiA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		7 / 12 THR A 142
GLY A 162
ILE A 188
ALA A 167
GLY A 166
ALA A 168
ILE A 227
 None
 1.30A 5kb6B-4yjiA:
undetectable		 5kb6B-4yjiA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 11 ALA A 172
GLY A 166
ALA A 160
THR A 150
LEU A 400
 None
 1.03A 5lf7H-4yjiA:
undetectable
5lf7I-4yjiA:
undetectable		 5lf7H-4yjiA:
21.09
5lf7I-4yjiA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 11 ALA A 172
GLY A 166
ALA A 160
THR A 150
LEU A 400
 None
 1.03A 5lf7V-4yjiA:
undetectable
5lf7W-4yjiA:
undetectable		 5lf7V-4yjiA:
21.09
5lf7W-4yjiA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 12 LEU A  97
ILE A 100
GLY A  99
THR A 142
SER A 133
 None
 1.25A 5nfjC-4yjiA:
undetectable		 5nfjC-4yjiA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		4 / 5 PHE A 297
VAL A 307
MET A 458
VAL A 296
 None
 1.41A 6ekzA-4yjiA:
undetectable		 6ekzA-4yjiA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4yji ARYL ACYLAMIDASE
(bacterium
CSBL00001) 		5 / 9 ILE A 286
ALA A 456
GLY A 457
GLY A 161
CYH A 402
 None
 1.03A 6nm4B-4yjiA:
undetectable		 6nm4B-4yjiA:
18.75