SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 4yjw DUF3829 FAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 TYR A 134
ILE A 151
LEU A  79
VAL A  76
 None
 0.83A 2w98B-4yjwA:
undetectable		 2w98B-4yjwA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 4yjw DUF3829 FAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 GLU A 155
LYS A 129
GLU A 126
ALA A 123
 None
 1.06A 6an0A-4yjwA:
undetectable		 6an0A-4yjwA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4yjw DUF3829 FAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 LEU A  54
GLY A 115
LEU A 117
THR A  92
VAL A  95
 None
 1.21A 6czmB-4yjwA:
undetectable
6czmC-4yjwA:
undetectable		 6czmB-4yjwA:
19.01
6czmC-4yjwA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4yjw DUF3829 FAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 LEU A  54
GLY A 115
LEU A 117
THR A  92
VAL A  95
 None
 1.14A 6czmD-4yjwA:
undetectable
6czmE-4yjwA:
undetectable		 6czmD-4yjwA:
19.01
6czmE-4yjwA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4yjw DUF3829 FAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 LEU A  54
GLY A 115
LEU A 117
THR A  92
VAL A  95
 None
 1.17A 6czmE-4yjwA:
undetectable
6czmF-4yjwA:
undetectable		 6czmE-4yjwA:
19.01
6czmF-4yjwA:
19.01