SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 5 HIS A 306
SER A 194
LEU A 108
GLY A 219
 None
 0.97A 1a4lB-4yjyA:
undetectable		 1a4lB-4yjyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 VAL A 320
LEU A 250
PHE A 374
THR A 248
GLY A 287
 None
 1.15A 1ia0B-4yjyA:
undetectable		 1ia0B-4yjyA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 8 THR A 135
GLY A 166
LEU A 266
GLY A 259
 None
 0.76A 1jhaA-4yjyA:
undetectable		 1jhaA-4yjyA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 GLY A 375
GLY A 171
GLY A 170
VAL A 382
GLY A 308
 None
 0.95A 1n2xB-4yjyA:
undetectable		 1n2xB-4yjyA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 5 PHE A 376
LEU A 313
VAL A 316
VAL A 372
 None
 1.18A 1t88B-4yjyA:
undetectable		 1t88B-4yjyA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 VAL A 320
LEU A 250
PHE A 374
THR A 248
GLY A 287
 None
 1.15A 1tubB-4yjyA:
undetectable		 1tubB-4yjyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 5 PHE A 376
LEU A 313
VAL A 316
VAL A 372
 None
 1.19A 2m56A-4yjyA:
undetectable		 2m56A-4yjyA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 ILE A 312
HIS A 306
PHE A 218
GLY A 219
LEU A 346
 None
 1.00A 2nyrB-4yjyA:
undetectable		 2nyrB-4yjyA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 11 ILE A 226
ALA A 113
LEU A 147
LEU A 153
ILE A 127
 None
 1.08A 2w9sA-4yjyA:
undetectable		 2w9sA-4yjyA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 8 ILE A 226
ALA A 113
LEU A 147
ILE A 127
 None
 0.66A 2w9sE-4yjyA:
undetectable		 2w9sE-4yjyA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 6 THR A 172
VAL A 173
GLU A 195
CYH A 193
 None
 1.13A 3b6rB-4yjyA:
undetectable		 3b6rB-4yjyA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		6 / 10 GLY A 375
VAL A 274
ILE A 257
GLY A 379
ILE A 249
ILE A 278
 None
 1.30A 3ekpD-4yjyA:
undetectable		 3ekpD-4yjyA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 8 VAL A 345
VAL A 372
PHE A 374
HIS A 306
 None
 1.02A 3fhxB-4yjyA:
undetectable		 3fhxB-4yjyA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFA_B_SAMB406_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE N)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 PHE A 374
PRO A 292
SER A 246
VAL A 382
ASN A 281
 None
 1.32A 3rfaB-4yjyA:
undetectable		 3rfaB-4yjyA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 5 ASP A 314
LEU A 313
ILE A 278
PRO A 275
 None
 1.13A 3s3vA-4yjyA:
undetectable		 3s3vA-4yjyA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 6 PHE A 376
LEU A 313
VAL A 316
VAL A 372
 None
 1.13A 4kkyX-4yjyA:
undetectable		 4kkyX-4yjyA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 5 PHE A 376
LEU A 313
VAL A 316
VAL A 372
 None
 1.20A 4l49A-4yjyA:
undetectable		 4l49A-4yjyA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 5 LEU A 322
ASP A 297
TRP A 298
ILE A 295
 None
 1.27A 4mwrA-4yjyA:
undetectable		 4mwrA-4yjyA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		6 / 11 GLY A 375
VAL A 274
ILE A 257
GLY A 379
ILE A 249
ILE A 278
 None
 1.33A 4njvC-4yjyA:
undetectable		 4njvC-4yjyA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 SER A 342
GLY A 171
GLY A 170
PHE A 168
GLN A 165
 None
 1.09A 4ubeA-4yjyA:
undetectable		 4ubeA-4yjyA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		3 / 3 ARG A  11
ASN A 184
ASP A 230
 None
 0.82A 5gwxA-4yjyA:
undetectable		 5gwxA-4yjyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 7 PHE A 376
GLY A 377
GLY A 379
THR A 135
 None
 0.67A 5ybbB-4yjyA:
undetectable		 5ybbB-4yjyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 ILE A 249
GLN A 247
THR A 172
VAL A 173
VAL A 176
 None
 1.08A 6bzoC-4yjyA:
undetectable		 6bzoC-4yjyA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		5 / 12 ILE A 249
THR A 248
GLN A 247
THR A 172
VAL A 176
 None
 0.97A 6bzoC-4yjyA:
undetectable		 6bzoC-4yjyA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4yjy CHALCONE SYNTHASE 1
(Oryza
sativa) 		4 / 8 ILE A 249
THR A 248
THR A 172
ARG A 175
 None
 0.85A 6c06C-4yjyA:
undetectable		 6c06C-4yjyA:
undetectable