SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ymk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 12 HIS A 157
HIS A 116
ALA A 306
HIS A 297
HIS A 298
 ZN  A 401 (-3.3A)
ZN  A 401 ( 3.5A)
None
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
 1.09A 1a4lA-4ymkA:
undetectable		 1a4lA-4ymkA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 12 HIS A 157
HIS A 116
ALA A 306
HIS A 297
HIS A 298
 ZN  A 401 (-3.3A)
ZN  A 401 ( 3.5A)
None
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
 1.03A 1a4lC-4ymkA:
undetectable		 1a4lC-4ymkA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 TRP A 119
ALA A 203
VAL A 207
 None
 0.96A 1av2C-4ymkA:
undetectable
1av2D-4ymkA:
undetectable		 1av2C-4ymkA:
8.89
1av2D-4ymkA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 VAL A 260
TRP A 258
TRP A 180
 ST9  A 403 (-4.4A)
ST9  A 403 (-4.2A)
None
 1.13A 1c4dA-4ymkA:
undetectable
1c4dB-4ymkA:
undetectable		 1c4dA-4ymkA:
8.89
1c4dB-4ymkA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 265
HIS A 153
HIS A 157
HIS A 298
 ZN  A 402 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 0.97A 1e9yB-4ymkA:
undetectable		 1e9yB-4ymkA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 10 ASN A 261
ASP A 165
HIS A 116
HIS A 153
HIS A 297
 ST9  A 403 (-3.5A)
None
ZN  A 401 ( 3.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.2A)
 1.37A 1ivvB-4ymkA:
undetectable		 1ivvB-4ymkA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 SER A 120
ARG A 154
HIS A 265
HIS A 298
 None
None
ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
 1.18A 1s19A-4ymkA:
undetectable		 1s19A-4ymkA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 TYR A 272
GLU A 280
TYR A 309
ILE A 282
 None
 1.13A 1tuvA-4ymkA:
undetectable		 1tuvA-4ymkA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.31A 1v54A-4ymkA:
undetectable
1v54C-4ymkA:
undetectable		 1v54A-4ymkA:
21.62
1v54C-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.31A 1v55A-4ymkA:
undetectable
1v55C-4ymkA:
undetectable		 1v55A-4ymkA:
21.62
1v55C-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 SER A 305
ALA A 306
SER A 307
THR A 317
 None
 0.73A 1yvpB-4ymkA:
undetectable		 1yvpB-4ymkA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 11 LEU A 109
ALA A 329
LEU A 328
MET A 323
LEU A 134
 None
 1.21A 2c12F-4ymkA:
undetectable		 2c12F-4ymkA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.31A 2dyrA-4ymkA:
undetectable
2dyrC-4ymkA:
undetectable		 2dyrA-4ymkA:
21.62
2dyrC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.32A 2eijA-4ymkA:
undetectable
2eijC-4ymkA:
undetectable		 2eijA-4ymkA:
21.62
2eijC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.33A 2eijN-4ymkA:
undetectable
2eijP-4ymkA:
undetectable		 2eijN-4ymkA:
21.62
2eijP-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.32A 2eikA-4ymkA:
undetectable
2eikC-4ymkA:
undetectable		 2eikA-4ymkA:
21.62
2eikC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.33A 2eikN-4ymkA:
undetectable
2eikP-4ymkA:
undetectable		 2eikN-4ymkA:
21.62
2eikP-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.30A 2eilN-4ymkA:
undetectable
2eilP-4ymkA:
undetectable		 2eilN-4ymkA:
21.62
2eilP-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.29A 2eimA-4ymkA:
undetectable
2eimC-4ymkA:
undetectable		 2eimA-4ymkA:
21.62
2eimC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 TYR A 104
ARG A 249
MET A 105
THR A 106
 MPG  A 404 (-3.4A)
None
MPG  A 404 (-3.5A)
None
 1.42A 2eimJ-4ymkA:
undetectable		 2eimJ-4ymkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.31A 2eimN-4ymkA:
undetectable
2eimP-4ymkA:
undetectable		 2eimN-4ymkA:
21.62
2eimP-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 TYR A 104
ARG A 249
MET A 105
THR A 106
 MPG  A 404 (-3.4A)
None
MPG  A 404 (-3.5A)
None
 1.41A 2eimW-4ymkA:
undetectable		 2eimW-4ymkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.32A 2einA-4ymkA:
undetectable
2einC-4ymkA:
undetectable		 2einA-4ymkA:
21.62
2einC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.07A 2fqeA-4ymkA:
undetectable		 2fqeA-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 SER A 305
ALA A 306
SER A 307
THR A 317
 None
 0.79A 2i91A-4ymkA:
undetectable		 2i91A-4ymkA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 SER A 305
ALA A 306
SER A 307
THR A 317
 None
 0.79A 2i91B-4ymkA:
undetectable		 2i91B-4ymkA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 8 HIS A 116
HIS A 153
HIS A 121
ALA A 306
 ZN  A 401 ( 3.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.4A)
None
 0.90A 2it4A-4ymkA:
undetectable		 2it4A-4ymkA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 ALA A 203
VAL A 207
TRP A 119
 None
 0.93A 2izqA-4ymkA:
undetectable
2izqB-4ymkA:
undetectable		 2izqA-4ymkA:
8.89
2izqB-4ymkA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 ALA A 338
THR A 339
ALA A 342
ARG A 346
 None
 0.88A 2ql8A-4ymkA:
undetectable
2ql8B-4ymkA:
undetectable		 2ql8A-4ymkA:
20.40
2ql8B-4ymkA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 116
HIS A 121
HIS A 153
HIS A 297
 ZN  A 401 ( 3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.2A)
 0.93A 2wkoA-4ymkA:
undetectable		 2wkoA-4ymkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 157
HIS A 156
HIS A 153
HIS A 298
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 402 (-3.4A)
 0.82A 2wkoA-4ymkA:
undetectable		 2wkoA-4ymkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 298
HIS A 297
HIS A 294
HIS A 157
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
 0.80A 2wkoA-4ymkA:
undetectable		 2wkoA-4ymkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 116
HIS A 121
HIS A 153
HIS A 297
 ZN  A 401 ( 3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.2A)
 0.98A 2wkoF-4ymkA:
undetectable		 2wkoF-4ymkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 157
HIS A 156
HIS A 153
HIS A 298
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 402 (-3.4A)
 0.88A 2wkoF-4ymkA:
undetectable		 2wkoF-4ymkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 298
HIS A 297
HIS A 294
HIS A 157
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
 0.85A 2wkoF-4ymkA:
undetectable		 2wkoF-4ymkA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.30A 2y69A-4ymkA:
undetectable
2y69C-4ymkA:
undetectable		 2y69A-4ymkA:
21.62
2y69C-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.28A 2zxwA-4ymkA:
undetectable
2zxwC-4ymkA:
undetectable		 2zxwA-4ymkA:
21.62
2zxwC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.29A 3abkA-4ymkA:
undetectable
3abkC-4ymkA:
undetectable		 3abkA-4ymkA:
21.62
3abkC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.27A 3abkN-4ymkA:
undetectable
3abkP-4ymkA:
undetectable		 3abkN-4ymkA:
21.62
3abkP-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.35A 3ag1A-4ymkA:
undetectable
3ag1C-4ymkA:
1.6		 3ag1A-4ymkA:
21.62
3ag1C-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.28A 3ag3A-4ymkA:
undetectable
3ag3C-4ymkA:
undetectable		 3ag3A-4ymkA:
21.62
3ag3C-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.28A 3ag3N-4ymkA:
undetectable
3ag3P-4ymkA:
undetectable		 3ag3N-4ymkA:
21.62
3ag3P-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.32A 3ag4A-4ymkA:
undetectable
3ag4C-4ymkA:
undetectable		 3ag4A-4ymkA:
21.62
3ag4C-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 6 HIS A 297
THR A 123
TYR A 304
HIS A 298
 ZN  A 401 (-3.2A)
None
None
ZN  A 402 (-3.4A)
 1.30A 3asnA-4ymkA:
undetectable
3asnC-4ymkA:
1.7		 3asnA-4ymkA:
21.62
3asnC-4ymkA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 HIS A 156
HIS A 298
HIS A 265
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
 0.58A 3qpkA-4ymkA:
undetectable		 3qpkA-4ymkA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 298
HIS A 157
HIS A 121
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 1.27A 3qpkA-4ymkA:
undetectable		 3qpkA-4ymkA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 HIS A 156
HIS A 298
HIS A 265
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
 0.58A 3qpkB-4ymkA:
undetectable		 3qpkB-4ymkA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 HIS A 298
HIS A 265
HIS A 156
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
 0.61A 3qpkB-4ymkA:
undetectable		 3qpkB-4ymkA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 298
HIS A 157
HIS A 121
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 1.27A 3qpkB-4ymkA:
undetectable		 3qpkB-4ymkA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 10 PHE A 319
VAL A 289
PHE A 315
PHE A 133
GLY A 110
 None
MPG  A 404 (-4.1A)
None
None
None
 1.27A 3t3rD-4ymkA:
undetectable		 3t3rD-4ymkA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 ASN A 314
ALA A 306
ARG A 117
 None
 0.90A 3tj7C-4ymkA:
undetectable
3tj7D-4ymkA:
undetectable		 3tj7C-4ymkA:
20.81
3tj7D-4ymkA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 8 HIS A 153
HIS A 121
HIS A 116
HIS A 298
 ZN  A 401 ( 3.2A)
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.5A)
ZN  A 402 (-3.4A)
 1.03A 3w6hA-4ymkA:
undetectable		 3w6hA-4ymkA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1226_0
(THAUMATIN-LIKE
PROTEIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 GLU A 148
TYR A 214
ASP A 145
PHE A 142
 None
None
None
ST9  A 403 (-4.3A)
 1.24A 3zs3A-4ymkA:
undetectable		 3zs3A-4ymkA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 157
HIS A 153
HIS A 298
HIS A 297
 ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
 0.96A 4ef3A-4ymkA:
undetectable		 4ef3A-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 298
HIS A 265
HIS A 157
HIS A 156
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 1.18A 4ef3A-4ymkA:
undetectable		 4ef3A-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 298
HIS A 294
HIS A 157
HIS A 156
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 1.03A 4ef3A-4ymkA:
undetectable		 4ef3A-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 157
HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.22A 4ef3A-4ymkA:
undetectable		 4ef3A-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 298
HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 1.10A 4ef3A-4ymkA:
undetectable		 4ef3A-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 7 ASP A 303
ASP A 321
ASN A 314
GLU A 291
 None
 1.14A 4feuB-4ymkA:
undetectable		 4feuB-4ymkA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 265
HIS A 153
HIS A 157
HIS A 298
 ZN  A 402 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 0.95A 4h9mA-4ymkA:
undetectable		 4h9mA-4ymkA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 LYS A 192
ALA A 164
SER A 160
THR A 162
 None
 1.38A 4i89B-4ymkA:
undetectable		 4i89B-4ymkA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 VAL A 335
SER A 336
THR A 339
 None
 0.18A 4luhA-4ymkA:
undetectable		 4luhA-4ymkA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 8 ILE A  50
HIS A 121
HIS A 116
HIS A 153
 None
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.5A)
ZN  A 401 ( 3.2A)
 0.79A 4n16A-4ymkA:
undetectable		 4n16A-4ymkA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 TYR A 269
PHE A 293
HIS A 352
LEU A 358
 None
 1.15A 5csyB-4ymkA:
undetectable		 5csyB-4ymkA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 THR A 317
SER A 305
TYR A 304
 None
 0.87A 5jsdA-4ymkA:
undetectable		 5jsdA-4ymkA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 THR A 317
SER A 305
TYR A 304
 None
 0.87A 5jsdB-4ymkA:
undetectable		 5jsdB-4ymkA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 THR A 317
SER A 305
TYR A 304
 None
 0.87A 5jsdC-4ymkA:
undetectable		 5jsdC-4ymkA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 THR A 317
SER A 305
TYR A 304
 None
 0.89A 5jseA-4ymkA:
undetectable		 5jseA-4ymkA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 THR A 317
SER A 305
TYR A 304
 None
 0.88A 5jseC-4ymkA:
undetectable		 5jseC-4ymkA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 157
HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.13A 5mejA-4ymkA:
undetectable		 5mejA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 298
HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 1.01A 5mejA-4ymkA:
undetectable		 5mejA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 6 HIS A 297
HIS A 298
HIS A 294
HIS A 157
HIS A 156
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 1.24A 5mejA-4ymkA:
undetectable		 5mejA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.07A 5mejA-4ymkA:
undetectable		 5mejA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 157
HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.13A 5mewA-4ymkA:
undetectable		 5mewA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 298
HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 1.01A 5mewA-4ymkA:
undetectable		 5mewA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 6 HIS A 297
HIS A 298
HIS A 294
HIS A 157
HIS A 156
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 1.24A 5mewA-4ymkA:
undetectable		 5mewA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.08A 5mewA-4ymkA:
undetectable		 5mewA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 157
HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.13A 5mhuA-4ymkA:
undetectable		 5mhuA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 298
HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 1.01A 5mhuA-4ymkA:
undetectable		 5mhuA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 6 HIS A 297
HIS A 298
HIS A 294
HIS A 157
HIS A 156
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 1.25A 5mhuA-4ymkA:
undetectable		 5mhuA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.06A 5mhuA-4ymkA:
undetectable		 5mhuA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 157
HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.14A 5mhvA-4ymkA:
undetectable		 5mhvA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 5 HIS A 298
HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 1.02A 5mhvA-4ymkA:
undetectable		 5mhvA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 6 HIS A 297
HIS A 298
HIS A 294
HIS A 157
HIS A 156
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.4A)
 1.25A 5mhvA-4ymkA:
undetectable		 5mhvA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.06A 5mhvA-4ymkA:
undetectable		 5mhvA-4ymkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 0.99A 5mhwA-4ymkA:
undetectable		 5mhwA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.89A 5mhwA-4ymkA:
undetectable		 5mhwA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.06A 5mhwA-4ymkA:
undetectable		 5mhwA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 0.99A 5mhxA-4ymkA:
undetectable		 5mhxA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.89A 5mhxA-4ymkA:
undetectable		 5mhxA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.06A 5mhxA-4ymkA:
undetectable		 5mhxA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 0.99A 5mhyA-4ymkA:
undetectable		 5mhyA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.90A 5mhyA-4ymkA:
undetectable		 5mhyA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5mhyA-4ymkA:
undetectable		 5mhyA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.00A 5mhzA-4ymkA:
undetectable		 5mhzA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.90A 5mhzA-4ymkA:
undetectable		 5mhzA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.06A 5mhzA-4ymkA:
undetectable		 5mhzA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 0.99A 5mi1A-4ymkA:
undetectable		 5mi1A-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.89A 5mi1A-4ymkA:
undetectable		 5mi1A-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5mi1A-4ymkA:
undetectable		 5mi1A-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 0.99A 5mi2A-4ymkA:
undetectable		 5mi2A-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.90A 5mi2A-4ymkA:
undetectable		 5mi2A-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5mi2A-4ymkA:
undetectable		 5mi2A-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.00A 5miaA-4ymkA:
undetectable		 5miaA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.91A 5miaA-4ymkA:
undetectable		 5miaA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5miaA-4ymkA:
undetectable		 5miaA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.00A 5mibA-4ymkA:
undetectable		 5mibA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.90A 5mibA-4ymkA:
undetectable		 5mibA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5mibA-4ymkA:
undetectable		 5mibA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.00A 5micA-4ymkA:
undetectable		 5micA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.91A 5micA-4ymkA:
undetectable		 5micA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.04A 5micA-4ymkA:
undetectable		 5micA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.00A 5midA-4ymkA:
undetectable		 5midA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.91A 5midA-4ymkA:
undetectable		 5midA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5midA-4ymkA:
undetectable		 5midA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 156
HIS A 297
HIS A 298
HIS A 294
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.1A)
 1.00A 5mieA-4ymkA:
undetectable		 5mieA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 297
HIS A 156
HIS A 157
HIS A 153
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
 0.91A 5mieA-4ymkA:
undetectable		 5mieA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5mieA-4ymkA:
undetectable		 5mieA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 HIS A 156
HIS A 298
HIS A 265
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.4A)
 0.58A 5migA-4ymkA:
undetectable		 5migA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 297
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.05A 5migA-4ymkA:
undetectable		 5migA-4ymkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 HIS A 167
ASP A 165
HIS A 156
 ST9  A 403 ( 4.7A)
None
ZN  A 402 (-3.4A)
 0.93A 5n1tW-4ymkA:
undetectable		 5n1tW-4ymkA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 MET A 198
GLU A 148
ARG A 151
 None
None
ST9  A 403 (-2.7A)
 0.81A 5tjyA-4ymkA:
undetectable		 5tjyA-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 MET A 198
GLU A 148
ARG A 151
 None
None
ST9  A 403 (-2.7A)
 0.87A 5tjzA-4ymkA:
undetectable		 5tjzA-4ymkA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 TYR A 104
ARG A 249
MET A 105
THR A 106
 MPG  A 404 (-3.4A)
None
MPG  A 404 (-3.5A)
None
 1.33A 5w97J-4ymkA:
undetectable		 5w97J-4ymkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		5 / 9 ILE A 282
GLY A 290
PHE A 293
ASN A 314
ALA A 256
 None
MPG  A 404 ( 4.9A)
None
None
ST9  A 403 ( 4.1A)
 1.39A 5x66C-4ymkA:
undetectable		 5x66C-4ymkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 HIS A 116
HIS A 121
HIS A 153
 ZN  A 401 ( 3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.2A)
 0.54A 5zrdA-4ymkA:
undetectable		 5zrdA-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 121
HIS A 153
HIS A 116
HIS A 297
 ZN  A 401 (-3.4A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
 1.02A 5zrdB-4ymkA:
undetectable		 5zrdB-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 153
HIS A 116
HIS A 121
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
 1.06A 5zrdB-4ymkA:
undetectable		 5zrdB-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 5 HIS A 157
HIS A 153
HIS A 121
HIS A 297
 ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
 0.99A 5zrdB-4ymkA:
undetectable		 5zrdB-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 116
HIS A 297
HIS A 121
HIS A 153
 ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.2A)
 1.16A 5zrdC-4ymkA:
undetectable		 5zrdC-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 121
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
 1.04A 5zrdC-4ymkA:
undetectable		 5zrdC-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 157
HIS A 153
HIS A 121
HIS A 297
 ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
 0.97A 5zrdC-4ymkA:
undetectable		 5zrdC-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 116
HIS A 297
HIS A 121
HIS A 153
 ZN  A 401 ( 3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.4A)
ZN  A 401 ( 3.2A)
 1.15A 5zrdD-4ymkA:
undetectable		 5zrdD-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 153
HIS A 116
HIS A 121
HIS A 157
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
 1.05A 5zrdD-4ymkA:
undetectable		 5zrdD-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		4 / 4 HIS A 157
HIS A 153
HIS A 121
HIS A 297
 ZN  A 401 (-3.3A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
 0.95A 5zrdD-4ymkA:
undetectable		 5zrdD-4ymkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4ymk ACYL-COA DESATURASE
1
(Mus
musculus) 		3 / 3 ARG A 154
LYS A 158
ARG A 346
 None
 1.24A 6c06D-4ymkA:
undetectable		 6c06D-4ymkA:
undetectable