SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ymp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 4ymp INTERNALIN
(Bacillus
anthracis) 		4 / 6 VAL A  61
MET A 101
PHE A 120
VAL A  92
 None
 1.15A 3soaA-4ympA:
undetectable		 3soaA-4ympA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4ymp INTERNALIN
(Bacillus
anthracis) 		4 / 6 ILE A  15
ILE A 118
PHE A  90
LEU A  59
 None
HEM  A 201 (-4.7A)
None
None
 0.95A 4m51A-4ympA:
undetectable		 4m51A-4ympA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 4ymp INTERNALIN
(Bacillus
anthracis) 		4 / 7 PHE A  56
LEU A  59
MET A 103
ALA A  48
 HEM  A 201 (-4.6A)
None
HEM  A 201 ( 3.8A)
None
 0.97A 4rjdB-4ympA:
undetectable		 4rjdB-4ympA:
19.85