SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ymr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 GLU A 297
LEU A 303
LEU A 300
LEU A 302
None
0.87A 1np1A-4ymrA:
undetectable
1np1A-4ymrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.38A 2yldA-4ymrA:
undetectable
2yldA-4ymrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.48A 2yldA-4ymrA:
undetectable
2yldA-4ymrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.41A 2ylgA-4ymrA:
undetectable
2ylgA-4ymrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.44A 2ylgA-4ymrA:
undetectable
2ylgA-4ymrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)
4ymr PROTEIN SNX21
(Mus
musculus)
5 / 10 PRO A 310
SER A 267
GLY A 268
LEU A 362
ASP A 363
None
1.17A 3lsfB-4ymrA:
undetectable
3lsfE-4ymrA:
undetectable
3lsfB-4ymrA:
22.92
3lsfE-4ymrA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.38A 3zwiA-4ymrA:
undetectable
3zwiA-4ymrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.49A 3zwiA-4ymrA:
undetectable
3zwiA-4ymrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 4 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.38A 4cipA-4ymrA:
1.8
4cipA-4ymrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 4 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.48A 4cipA-4ymrA:
1.8
4cipA-4ymrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.38A 5jliA-4ymrA:
undetectable
5jliA-4ymrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.45A 5jliA-4ymrA:
undetectable
5jliA-4ymrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 4 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.38A 5jslA-4ymrA:
1.8
5jslA-4ymrA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 4 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.46A 5jslA-4ymrA:
1.8
5jslA-4ymrA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 251
GLY A 278
CYH A 282
HIS A 283
None
1.41A 5jt4A-4ymrA:
undetectable
5jt4A-4ymrA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 5 ALA A 254
GLY A 278
CYH A 282
HIS A 283
None
1.45A 5jt4A-4ymrA:
undetectable
5jt4A-4ymrA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 4 LYS A 298
LEU A 276
ALA A 294
LEU A 279
None
1.48A 6gnrA-4ymrA:
undetectable
6gnrA-4ymrA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)
4ymr PROTEIN SNX21
(Mus
musculus)
4 / 4 LYS A 298
LEU A 276
ALA A 294
LEU A 279
None
1.47A 6gnrB-4ymrA:
undetectable
6gnrB-4ymrA:
21.02