SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		4 / 5 MET A  33
ALA A  37
ILE A 113
ASP A 230
 EDO  A 405 ( 3.5A)
None
None
None
 1.14A 1upfA-4yn1A:
undetectable		 1upfA-4yn1A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		4 / 5 MET A  33
ALA A  37
ILE A 113
ASP A 230
 EDO  A 405 ( 3.5A)
None
None
None
 1.10A 1upfC-4yn1A:
undetectable		 1upfC-4yn1A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		4 / 7 VAL A 165
PHE A 158
THR A 155
ARG A 205
 None
 1.19A 2kotA-4yn1A:
undetectable		 2kotA-4yn1A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		5 / 12 HIS A   1
GLY A   2
VAL A 221
GLY A 224
PHE A 105
 None
 1.04A 3keeB-4yn1A:
undetectable		 3keeB-4yn1A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		5 / 12 HIS A   1
GLY A   2
VAL A 221
GLY A 224
PHE A 105
 None
 1.00A 3keeC-4yn1A:
undetectable		 3keeC-4yn1A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		4 / 6 THR A 131
ILE A 132
THR A 207
PHE A 209
 None
EDO  A 406 ( 3.6A)
None
None
 1.00A 4acbC-4yn1A:
undetectable		 4acbC-4yn1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 4yn1 FUSOLIN
(Anomala
cuprea
entomopoxvirus) 		4 / 8 GLY A 224
GLN A 216
PHE A 138
TYR A 196
 None
 0.86A 6eqpA-4yn1A:
undetectable		 6eqpA-4yn1A:
11.31