SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ynh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 247
LEU A 237
PHE A 243
LEU A 230
 None
 0.83A 2eijN-4ynhA:
undetectable
2eijW-4ynhA:
undetectable		 2eijN-4ynhA:
8.11
2eijW-4ynhA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 247
LEU A 237
PHE A 243
LEU A 230
 None
 0.83A 2eilN-4ynhA:
undetectable
2eilW-4ynhA:
undetectable		 2eilN-4ynhA:
8.11
2eilW-4ynhA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 247
LEU A 237
PHE A 243
LEU A 230
 None
 0.79A 3ablN-4ynhA:
undetectable
3ablW-4ynhA:
undetectable		 3ablN-4ynhA:
8.11
3ablW-4ynhA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 247
LEU A 237
PHE A 243
LEU A 230
 None
 0.78A 3asnN-4ynhA:
undetectable
3asnW-4ynhA:
undetectable		 3asnN-4ynhA:
8.11
3asnW-4ynhA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		3 / 3 MET A 242
GLN A 245
ARG A 244
 None
 1.08A 5m35B-4ynhA:
undetectable		 5m35B-4ynhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		3 / 3 MET A 242
GLN A 245
ARG A 244
 None
 1.06A 5m36A-4ynhA:
undetectable		 5m36A-4ynhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 247
LEU A 237
PHE A 243
LEU A 230
 None
 0.76A 5xdxN-4ynhA:
undetectable
5xdxW-4ynhA:
undetectable		 5xdxN-4ynhA:
8.11
5xdxW-4ynhA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 247
LEU A 237
PHE A 243
LEU A 230
 None
 0.79A 5zcqN-4ynhA:
undetectable
5zcqW-4ynhA:
undetectable		 5zcqN-4ynhA:
8.11
5zcqW-4ynhA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		3 / 3 MET A 242
GLN A 245
ARG A 244
 None
 1.08A 6fn9A-4ynhA:
undetectable		 6fn9A-4ynhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		3 / 3 MET A 242
GLN A 245
ARG A 244
 None
 1.08A 6fnaB-4ynhA:
undetectable		 6fnaB-4ynhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		3 / 3 MET A 242
GLN A 245
ARG A 244
 None
 1.07A 6fnbA-4ynhA:
undetectable		 6fnbA-4ynhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ynh SPINDLE ASSEMBLY
ABNORMAL PROTEIN 5
(Caenorhabditis
elegans) 		4 / 8 ILE A 232
ALA A 215
VAL A 218
ARG A 216
 None
 1.00A 6hu9a-4ynhA:
undetectable
6hu9e-4ynhA:
undetectable		 6hu9a-4ynhA:
7.46
6hu9e-4ynhA:
18.60