SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ynu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 GLU A 311
ILE A 425
ALA A 436
ILE A 438
THR A 509
 None
 1.39A 1aj6A-4ynuA:
undetectable		 1aj6A-4ynuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 VAL A 107
VAL A 103
TRP A 108
 None
 0.86A 1bdwA-4ynuA:
undetectable
1bdwB-4ynuA:
undetectable		 1bdwA-4ynuA:
2.96
1bdwB-4ynuA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ASP A  62
GLY A  58
ASP A  46
THR A  89
ILE A  92
 None
None
None
FAD  A 601 (-3.6A)
None
 1.10A 1c6zA-4ynuA:
undetectable		 1c6zA-4ynuA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 GLY A  83
ALA A  56
THR A  91
ILE A  61
GLY A  94
 None
None
None
None
FAD  A 601 (-3.0A)
 1.16A 1c9sN-4ynuA:
undetectable
1c9sO-4ynuA:
undetectable		 1c9sN-4ynuA:
9.14
1c9sO-4ynuA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 GLY A  83
ALA A  56
THR A  91
ILE A  61
GLY A  94
 None
None
None
None
FAD  A 601 (-3.0A)
 1.19A 1c9sQ-4ynuA:
undetectable
1c9sR-4ynuA:
undetectable		 1c9sQ-4ynuA:
9.14
1c9sR-4ynuA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 GLY A  94
GLY A  83
ALA A  56
THR A  91
ILE A  61
 FAD  A 601 (-3.0A)
None
None
None
None
 1.18A 1c9sL-4ynuA:
undetectable
1c9sV-4ynuA:
undetectable		 1c9sL-4ynuA:
9.14
1c9sV-4ynuA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 GLY A  83
ALA A  56
THR A  91
ILE A  61
GLY A  94
 None
None
None
None
FAD  A 601 (-3.0A)
 1.20A 1gtfR-4ynuA:
undetectable
1gtfS-4ynuA:
undetectable		 1gtfR-4ynuA:
9.14
1gtfS-4ynuA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ARG A 381
LEU A 382
PRO A 307
GLY A 519
 None
 0.83A 1hrkA-4ynuA:
undetectable		 1hrkA-4ynuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ARG A 381
LEU A 382
PRO A 307
GLY A 519
 None
 0.83A 1hrkB-4ynuA:
undetectable		 1hrkB-4ynuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 ASP A 393
LEU A 385
LEU A 389
 None
 0.71A 1ikeA-4ynuA:
undetectable		 1ikeA-4ynuA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 GLU A 101
LYS A 394
VAL A 395
 None
 0.84A 1l2iA-4ynuA:
undetectable		 1l2iA-4ynuA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 LEU A  33
VAL A 540
ILE A 273
ARG A 559
 None
 1.13A 1opjB-4ynuA:
undetectable		 1opjB-4ynuA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 11 GLY A  87
SER A  90
ALA A 214
ALA A 216
LEU A 156
 None
 1.11A 1ukbA-4ynuA:
undetectable		 1ukbA-4ynuA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 GLY A  83
ALA A  56
THR A  91
ILE A  61
GLY A  94
 None
None
None
None
FAD  A 601 (-3.0A)
 1.20A 1utdU-4ynuA:
undetectable
1utdV-4ynuA:
undetectable		 1utdU-4ynuA:
9.14
1utdV-4ynuA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 ARG A 501
TYR A  53
ASN A 503
HIS A 505
ALA A  96
 LGC  A 602 ( 2.8A)
LGC  A 602 ( 4.5A)
LGC  A 602 (-3.4A)
LGC  A 602 (-3.7A)
FAD  A 601 (-4.6A)
 0.99A 2bnnA-4ynuA:
undetectable
2bnnB-4ynuA:
undetectable		 2bnnA-4ynuA:
19.13
2bnnB-4ynuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 TYR A  53
ASN A 503
HIS A 505
ALA A  96
 LGC  A 602 ( 4.5A)
LGC  A 602 (-3.4A)
LGC  A 602 (-3.7A)
FAD  A 601 (-4.6A)
 0.72A 2bnnA-4ynuA:
undetectable
2bnnB-4ynuA:
undetectable		 2bnnA-4ynuA:
19.13
2bnnB-4ynuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLY A  12
GLY A  14
ALA A  37
THR A 234
ALA A 235
 FAD  A 601 (-3.3A)
FAD  A 601 (-3.4A)
FAD  A 601 (-3.6A)
FAD  A 601 (-4.3A)
FAD  A 601 (-3.5A)
 0.89A 2gluA-4ynuA:
3.7		 2gluA-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLY A  12
GLY A  14
ALA A  37
ALA A 235
ALA A 275
 FAD  A 601 (-3.3A)
FAD  A 601 (-3.4A)
FAD  A 601 (-3.6A)
FAD  A 601 (-3.5A)
FAD  A 601 (-3.8A)
 0.99A 2gluB-4ynuA:
3.3		 2gluB-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLY A  12
GLY A  14
ALA A  37
THR A 234
ALA A 235
 FAD  A 601 (-3.3A)
FAD  A 601 (-3.4A)
FAD  A 601 (-3.6A)
FAD  A 601 (-4.3A)
FAD  A 601 (-3.5A)
 0.91A 2gluB-4ynuA:
3.3		 2gluB-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 SER A 257
HIS A 228
ASP A   7
 None
 0.78A 2oxtA-4ynuA:
undetectable		 2oxtA-4ynuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 5 PHE A  57
SER A 412
PHE A 504
ILE A 400
 FAD  A 601 (-4.5A)
None
FAD  A 601 (-4.2A)
None
 1.39A 2v0mD-4ynuA:
undetectable		 2v0mD-4ynuA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 LEU A 278
GLY A 276
LEU A  80
ALA A 538
GLY A 423
 None
FAD  A 601 (-3.5A)
None
FAD  A 601 (-3.5A)
None
 1.00A 2vmyA-4ynuA:
undetectable		 2vmyA-4ynuA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 TYR A  53
GLU A 413
ASN A 319
 LGC  A 602 ( 4.5A)
LGC  A 602 (-2.9A)
None
 0.96A 2y7hC-4ynuA:
undetectable		 2y7hC-4ynuA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 4 LEU A 329
ARG A 464
LEU A 468
ALA A 473
 None
 1.12A 3b9mA-4ynuA:
3.0		 3b9mA-4ynuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 LEU A  18
PRO A 506
GLY A 276
GLY A  13
LEU A  86
 None
None
FAD  A 601 (-3.5A)
FAD  A 601 ( 4.6A)
None
 0.96A 3e23A-4ynuA:
undetectable		 3e23A-4ynuA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ILE A 427
ASN A 371
HIS A 373
GLY A 290
 None
 0.89A 3em0B-4ynuA:
0.9		 3em0B-4ynuA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		6 / 12 VAL A  11
GLY A  12
GLY A  14
GLU A  36
ALA A 235
ILE A 283
 None
FAD  A 601 (-3.3A)
FAD  A 601 (-3.4A)
FAD  A 601 (-2.7A)
FAD  A 601 (-3.5A)
None
 1.06A 3fuuA-4ynuA:
undetectable		 3fuuA-4ynuA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 LEU A  33
VAL A 540
ILE A 273
ARG A 559
 None
 1.10A 3ik3A-4ynuA:
undetectable		 3ik3A-4ynuA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 LEU A  33
VAL A 540
ILE A 273
ARG A 559
 None
 1.07A 3ik3B-4ynuA:
undetectable		 3ik3B-4ynuA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLY A  13
ALA A 213
ALA A 214
LEU A  35
LEU A  86
 FAD  A 601 ( 4.6A)
None
None
None
None
 1.19A 3mteA-4ynuA:
6.5		 3mteA-4ynuA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 LEU A  33
VAL A 540
ILE A 273
ARG A 559
VAL A  19
 None
 1.44A 3oxzA-4ynuA:
undetectable		 3oxzA-4ynuA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 VAL A 533
ILE A 272
GLY A  17
SER A  16
ALA A 557
 None
None
None
FAD  A 601 (-2.8A)
None
 1.20A 4fwdA-4ynuA:
undetectable		 4fwdA-4ynuA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 532
ALA A 250
VAL A 289
ARG A 303
 None
 1.04A 4ijiH-4ynuA:
undetectable		 4ijiH-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 532
ALA A 250
VAL A 304
ARG A 303
 None
 1.09A 4ijiH-4ynuA:
undetectable		 4ijiH-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ILE A 272
GLY A  14
GLY A  12
ALA A  21
ALA A 213
 None
FAD  A 601 (-3.4A)
FAD  A 601 (-3.3A)
None
None
 1.10A 4kicB-4ynuA:
3.6		 4kicB-4ynuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 5 TYR A 125
THR A 552
HIS A 505
TYR A 337
 None
None
LGC  A 602 (-3.7A)
None
 1.43A 4oltB-4ynuA:
undetectable		 4oltB-4ynuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 5 GLN A 138
LEU A 164
SER A 163
ASP A 212
 None
 1.16A 4qtuD-4ynuA:
undetectable		 4qtuD-4ynuA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ALA A 511
GLU A 285
HIS A 426
GLU A 311
LEU A 382
 None
 1.45A 4r7lA-4ynuA:
undetectable		 4r7lA-4ynuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 ALA A 511
HIS A 426
GLU A 285
GLU A 311
LEU A 382
 None
 1.49A 4r7lA-4ynuA:
undetectable		 4r7lA-4ynuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.44A 4v2yA-4ynuA:
undetectable		 4v2yA-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.34A 4v2yB-4ynuA:
undetectable		 4v2yB-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.42A 4v2zA-4ynuA:
undetectable		 4v2zA-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.33A 4v2zB-4ynuA:
undetectable		 4v2zB-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.43A 4v30A-4ynuA:
undetectable		 4v30A-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.38A 4v30B-4ynuA:
undetectable		 4v30B-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 VAL A  19
TYR A 554
ALA A 557
 None
 0.55A 4ybnA-4ynuA:
undetectable		 4ybnA-4ynuA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 LEU A 282
LEU A 286
SER A 287
VAL A 535
 None
 1.23A 5a6iA-4ynuA:
undetectable		 5a6iA-4ynuA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.43A 5amiA-4ynuA:
undetectable		 5amiA-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.32A 5amiB-4ynuA:
undetectable		 5amiB-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.46A 5amjA-4ynuA:
undetectable		 5amjA-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.36A 5amjB-4ynuA:
undetectable		 5amjB-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.26A 5amkA-4ynuA:
undetectable		 5amkA-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.44A 5amkB-4ynuA:
undetectable		 5amkB-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 GLY A 252
ALA A 235
VAL A 253
GLU A 254
ILE A   9
 None
FAD  A 601 (-3.5A)
None
None
None
 1.22A 5i3cB-4ynuA:
undetectable		 5i3cB-4ynuA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 GLY A  88
ASP A 315
ILE A 425
TYR A  65
 FAD  A 601 (-3.0A)
None
None
None
 1.14A 5iwuA-4ynuA:
undetectable		 5iwuA-4ynuA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 5 VAL A 335
THR A  98
ASN A 189
ASP A 187
 None
 1.23A 5m0iB-4ynuA:
undetectable		 5m0iB-4ynuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 PRO A 338
TYR A 458
ILE A 459
TYR A 337
THR A 336
 None
 1.43A 5mvnB-4ynuA:
undetectable		 5mvnB-4ynuA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 9 PRO A 338
TYR A 458
ILE A 459
TYR A 337
THR A 336
 None
 1.45A 5mvnC-4ynuA:
0.9		 5mvnC-4ynuA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 10 PRO A 338
TYR A 458
ILE A 459
TYR A 337
THR A 336
 None
 1.43A 5mzrC-4ynuA:
undetectable		 5mzrC-4ynuA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.41A 5oh1A-4ynuA:
undetectable		 5oh1A-4ynuA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.34A 5oh1B-4ynuA:
undetectable		 5oh1B-4ynuA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.47A 5oh3A-4ynuA:
undetectable		 5oh3A-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 7 ASN A 318
PHE A 414
TRP A 415
TYR A 337
 LGC  A 602 ( 4.4A)
None
None
None
 1.39A 5oh3B-4ynuA:
undetectable		 5oh3B-4ynuA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 8 THR A  15
GLY A  14
GLY A  88
ALA A  82
 FAD  A 601 (-3.2A)
FAD  A 601 (-3.4A)
FAD  A 601 (-3.0A)
FAD  A 601 ( 4.8A)
 0.70A 5vw5A-4ynuA:
2.8		 5vw5A-4ynuA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 LEU A 306
VAL A 521
ASP A 522
 None
 0.55A 5x23A-4ynuA:
undetectable		 5x23A-4ynuA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		5 / 12 GLY A  12
GLY A  14
VAL A  19
ALA A 235
ALA A 275
 FAD  A 601 (-3.3A)
FAD  A 601 (-3.4A)
None
FAD  A 601 (-3.5A)
FAD  A 601 (-3.8A)
 0.96A 5x7fA-4ynuA:
4.5		 5x7fA-4ynuA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		3 / 3 ARG A 501
LYS A 477
ARG A  81
 LGC  A 602 ( 2.8A)
LGC  A 603 ( 4.9A)
None
 1.30A 6az3C-4ynuA:
undetectable
6az3L-4ynuA:
undetectable
6az3M-4ynuA:
undetectable		 6az3C-4ynuA:
10.04
6az3L-4ynuA:
8.17
6az3M-4ynuA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 6 TYR A  65
ILE A 438
ALA A 277
ARG A 279
 None
None
None
FAD  A 601 (-3.6A)
 1.13A 6hu9m-4ynuA:
undetectable
6hu9q-4ynuA:
undetectable		 6hu9m-4ynuA:
23.85
6hu9q-4ynuA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 4 HIS A 505
LEU A 401
TYR A 199
GLY A  94
 LGC  A 602 (-3.7A)
None
None
FAD  A 601 (-3.0A)
 1.11A 6n91A-4ynuA:
undetectable		 6n91A-4ynuA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 4ynu GLUCOSE OXIDASE,
PUTATIVE
(Aspergillus
flavus) 		4 / 4 HIS A 505
LEU A 401
TYR A 199
GLY A  94
 LGC  A 602 (-3.7A)
None
None
FAD  A 601 (-3.0A)
 1.15A 6n91B-4ynuA:
undetectable		 6n91B-4ynuA:
9.11