SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		5 / 12 ASP A 234
LEU A 238
MET A 216
LEU A 215
ILE A 226
 None
 1.21A 1errA-4yo7A:
undetectable		 1errA-4yo7A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		5 / 12 ILE A 148
GLY A 151
GLY A 186
ASN A 187
ASN A 232
 None
 1.03A 1likA-4yo7A:
3.9		 1likA-4yo7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		5 / 9 ILE A 124
ILE A 127
GLY A  46
ALA A 101
THR A 140
 None
 1.23A 2dtjA-4yo7A:
undetectable
2dtjB-4yo7A:
undetectable		 2dtjA-4yo7A:
19.88
2dtjB-4yo7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		3 / 3 ASP A 108
ASP A  83
ASP A 114
 None
 0.71A 2igtA-4yo7A:
4.8		 2igtA-4yo7A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		5 / 12 ASN A 233
ARG A 183
GLY A 176
ASP A 108
THR A 109
 INS  A 405 (-3.8A)
INS  A 405 (-2.6A)
None
None
None
 1.40A 3a25A-4yo7A:
undetectable		 3a25A-4yo7A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		4 / 4 THR A 224
VAL A 229
GLY A 203
THR A 204
 None
 0.55A 3cflA-4yo7A:
2.3		 3cflA-4yo7A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		4 / 6 GLU A 299
TYR A  70
ASP A  72
LYS A  43
 None
 1.27A 3pocB-4yo7A:
undetectable		 3pocB-4yo7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		4 / 8 ILE A 258
ILE A 148
MET A 305
GLY A 144
 None
 0.87A 4hdlA-4yo7A:
undetectable		 4hdlA-4yo7A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)
(Bacillus
halodurans) 		5 / 8 VAL A  47
ASN A 105
PRO A 106
GLN A 284
ILE A 127
 None
 1.28A 4iilA-4yo7A:
19.1		 4iilA-4yo7A:
23.18