SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4yok PUTATIVE FLAGELLAR
PROTEIN FLIS
(Parabacteroides
merdae) 		4 / 7 ALA A 189
LEU A 187
ALA A 140
PHE A 142
 None
 0.99A 2vcvL-4yokA:
undetectable		 2vcvL-4yokA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4yok PUTATIVE FLAGELLAR
PROTEIN FLIS
(Parabacteroides
merdae) 		4 / 8 ASP A 168
ASN A 171
GLY A  49
GLN A  75
 None
None
GOL  A 302 (-4.6A)
None
 0.96A 4af0A-4yokA:
undetectable		 4af0A-4yokA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4yok PUTATIVE FLAGELLAR
PROTEIN FLIS
(Parabacteroides
merdae) 		4 / 7 SER A 161
ASP A 176
ARG A 155
GLY A 208
 None
 0.95A 5btaA-4yokA:
undetectable
5btaC-4yokA:
undetectable
5btaD-4yokA:
undetectable		 5btaA-4yokA:
18.63
5btaC-4yokA:
18.63
5btaD-4yokA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4yok PUTATIVE FLAGELLAR
PROTEIN FLIS
(Parabacteroides
merdae) 		4 / 7 SER A 161
ASP A 176
ARG A 155
GLY A 208
 None
 0.97A 5btfA-4yokA:
undetectable
5btfB-4yokA:
undetectable
5btfC-4yokA:
undetectable		 5btfA-4yokA:
18.63
5btfB-4yokA:
23.55
5btfC-4yokA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4yok PUTATIVE FLAGELLAR
PROTEIN FLIS
(Parabacteroides
merdae) 		4 / 7 SER A 161
ASP A 176
ARG A 155
GLY A 208
 None
 0.96A 5btfA-4yokA:
undetectable
5btfC-4yokA:
undetectable
5btfD-4yokA:
undetectable		 5btfA-4yokA:
18.63
5btfC-4yokA:
18.63
5btfD-4yokA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 4yok PUTATIVE FLAGELLAR
PROTEIN FLIS
(Parabacteroides
merdae) 		4 / 7 VAL A  73
LEU A  47
LEU A  56
LEU A  90
 None
 0.67A 5jq7A-4yokA:
undetectable		 5jq7A-4yokA:
21.30