SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ypn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4ypn LON PROTEASE
(Meiothermus
taiwanensis) 		4 / 5 VAL A 262
VAL A 256
GLY A 257
TRP A 298
 None
 1.14A 2p2fA-4ypnA:
undetectable		 2p2fA-4ypnA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4ypn LON PROTEASE
(Meiothermus
taiwanensis) 		3 / 3 SER A 280
GLU A 269
ASP A 457
 None
 0.65A 2zulA-4ypnA:
undetectable		 2zulA-4ypnA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4ypn LON PROTEASE
(Meiothermus
taiwanensis) 		3 / 3 SER A 280
GLU A 269
ASP A 457
 None
 0.68A 3dmhA-4ypnA:
undetectable		 3dmhA-4ypnA:
25.81