SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ypv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		4 / 8 GLY A  87
SER A 159
PHE A 207
HIS A 283
 None
 0.84A 1ax9A-4ypvA:
17.7		 1ax9A-4ypvA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		6 / 12 GLY A  86
GLY A  87
GLY A  88
SER A 159
PHE A 207
HIS A 283
 None
 0.46A 1dx6A-4ypvA:
18.5		 1dx6A-4ypvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLY A  88
SER A 159
PHE A 216
PHE A 207
HIS A 283
 None
 1.02A 1dx6A-4ypvA:
18.5		 1dx6A-4ypvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.08A 1dz4A-4ypvA:
undetectable		 1dz4A-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.11A 1dz4B-4ypvA:
undetectable		 1dz4B-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 8 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.06A 1dz9A-4ypvA:
undetectable		 1dz9A-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLY A  86
TYR A  83
SER A 159
PHE A 216
HIS A 283
 None
 1.29A 1maaC-4ypvA:
18.9		 1maaC-4ypvA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLY A  86
GLY A  87
GLY A  88
SER A 159
HIS A 283
 None
 0.29A 1qtiA-4ypvA:
4.3		 1qtiA-4ypvA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.05A 1t85A-4ypvA:
undetectable		 1t85A-4ypvA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 5 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.12A 1t88B-4ypvA:
undetectable		 1t88B-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		6 / 12 GLY A  86
GLY A  87
GLY A  88
SER A 159
PHE A 207
HIS A 283
 None
 0.73A 1w6rA-4ypvA:
18.6		 1w6rA-4ypvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		6 / 12 GLY A  86
GLY A  88
SER A 159
PHE A 216
PHE A 207
HIS A 283
 None
 1.04A 1w6rA-4ypvA:
18.6		 1w6rA-4ypvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 11 GLY A  87
GLY A  88
SER A 159
PHE A 207
HIS A 283
 None
 0.36A 1w76A-4ypvA:
17.8		 1w76A-4ypvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 11 GLY A  88
SER A 159
PHE A 216
PHE A 207
HIS A 283
 None
 0.97A 1w76A-4ypvA:
17.8		 1w76A-4ypvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 4ypv EST8
(Parvibaculum) 		5 / 12 ALA A  30
GLY A  87
GLY A  88
SER A 159
HIS A 283
 None
 0.57A 1ya4A-4ypvA:
19.1		 1ya4A-4ypvA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		6 / 9 GLY A  86
GLY A  87
SER A 159
ALA A 160
PHE A 207
HIS A 283
 None
 1.07A 2aceA-4ypvA:
2.2		 2aceA-4ypvA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		6 / 9 GLY A  86
SER A 159
ALA A 160
PHE A 216
PHE A 207
HIS A 283
 None
 1.14A 2aceA-4ypvA:
2.2		 2aceA-4ypvA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		7 / 9 GLY A  87
GLY A  88
SER A 159
ALA A 160
PHE A 216
PHE A 207
HIS A 283
 None
 0.84A 2aceA-4ypvA:
2.2		 2aceA-4ypvA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.01A 2cppA-4ypvA:
undetectable		 2cppA-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.07A 2feuA-4ypvA:
undetectable		 2feuA-4ypvA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.04A 2feuB-4ypvA:
undetectable		 2feuB-4ypvA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLN A 289
LEU A 306
ALA A  99
CYH A 101
VAL A 112
 None
 1.18A 2g70A-4ypvA:
undetectable		 2g70A-4ypvA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLN A 289
LEU A 306
ALA A  99
CYH A 101
VAL A 112
 None
 1.22A 2g70B-4ypvA:
undetectable		 2g70B-4ypvA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLN A 289
LEU A 306
ALA A  99
CYH A 101
VAL A 112
 None
 1.30A 2g72B-4ypvA:
2.6		 2g72B-4ypvA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 8 GLY A  87
GLY A  88
ALA A 160
PHE A 216
HIS A 283
 None
 0.95A 2ha4A-4ypvA:
5.7		 2ha4A-4ypvA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 7 GLY A  87
GLY A  88
ALA A 160
PHE A 216
HIS A 283
 None
 0.96A 2ha4B-4ypvA:
19.6		 2ha4B-4ypvA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 5 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.09A 2m56A-4ypvA:
undetectable		 2m56A-4ypvA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 4ypv EST8
(Parvibaculum) 		4 / 7 LEU A 184
PHE A 104
ILE A 186
ASN A 287
 None
 0.89A 2opxA-4ypvA:
3.8		 2opxA-4ypvA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ypv EST8
(Parvibaculum) 		5 / 12 ILE A  22
HIS A  97
ALA A 290
LEU A  10
ILE A  37
 None
 1.26A 2xkwB-4ypvA:
undetectable		 2xkwB-4ypvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.20A 2zawA-4ypvA:
undetectable		 2zawA-4ypvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 LEU A 239
LEU A 242
SER A 169
VAL A 155
VAL A 247
 None
 1.23A 3aqiB-4ypvA:
2.8		 3aqiB-4ypvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 4ypv EST8
(Parvibaculum) 		4 / 4 ARG A 230
ASP A 225
ASP A 228
PRO A 229
 None
 1.27A 3fgrB-4ypvA:
undetectable		 3fgrB-4ypvA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.03A 3fwfA-4ypvA:
undetectable		 3fwfA-4ypvA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.07A 3fwgA-4ypvA:
undetectable		 3fwgA-4ypvA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.08A 3fwgB-4ypvA:
undetectable		 3fwgB-4ypvA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		4 / 7 GLY A  87
GLY A  88
SER A 159
HIS A 283
 None
 0.25A 3o9mA-4ypvA:
4.5		 3o9mA-4ypvA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 GLY A  87
GLY A  88
SER A 159
HIS A 283
 None
 0.33A 3o9mB-4ypvA:
8.6		 3o9mB-4ypvA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4ypv EST8
(Parvibaculum) 		3 / 3 THR A 249
ASP A 257
GLU A 201
 None
 0.82A 3qowA-4ypvA:
2.0		 3qowA-4ypvA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4ypv EST8
(Parvibaculum) 		3 / 3 TYR A  68
ASP A  93
ASP A  98
 None
 0.56A 3r24A-4ypvA:
undetectable		 3r24A-4ypvA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 LEU A 255
GLY A 251
ASN A 277
ILE A 282
ALA A   7
 None
 1.04A 3uwlD-4ypvA:
undetectable		 3uwlD-4ypvA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 4ypv EST8
(Parvibaculum) 		5 / 12 HIS A 283
GLY A  88
GLY A  86
TYR A 187
ALA A 120
 None
 1.11A 3vywB-4ypvA:
undetectable		 3vywB-4ypvA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 4ypv EST8
(Parvibaculum) 		5 / 12 HIS A 283
GLY A  88
GLY A  86
TYR A 187
ALA A 120
 None
 1.08A 3vywD-4ypvA:
undetectable		 3vywD-4ypvA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ypv EST8
(Parvibaculum) 		5 / 12 LEU A 239
LEU A 242
SER A 169
VAL A 155
VAL A 247
 None
 1.24A 3w1wA-4ypvA:
undetectable		 3w1wA-4ypvA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 ALA A 290
ASP A 158
ILE A 186
ASP A  42
HIS A  97
 None
 1.43A 3wemA-4ypvA:
undetectable		 3wemA-4ypvA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 ALA A 290
ASP A 158
ILE A 186
ASP A  42
HIS A  97
 None
 1.44A 3wenA-4ypvA:
undetectable		 3wenA-4ypvA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 ALA A 290
ASP A 158
ILE A 186
ASP A  42
HIS A  97
 None
 1.44A 3weoA-4ypvA:
undetectable		 3weoA-4ypvA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.07A 3wrhE-4ypvA:
undetectable		 3wrhE-4ypvA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.05A 3wrjE-4ypvA:
undetectable		 3wrjE-4ypvA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.05A 3wrmF-4ypvA:
undetectable		 3wrmF-4ypvA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 ASN A 287
LEU A  81
GLY A 162
SER A 159
ILE A 186
 None
 1.46A 4djeA-4ypvA:
undetectable		 4djeA-4ypvA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLY A  86
GLY A  87
GLY A  88
SER A 159
HIS A 283
 None
 0.22A 4ey6A-4ypvA:
19.7		 4ey6A-4ypvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		6 / 12 GLY A  86
GLY A  87
GLY A  88
SER A 159
PHE A 216
HIS A 283
 None
 0.97A 4ey6B-4ypvA:
18.5		 4ey6B-4ypvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 11 GLY A  87
SER A 159
TRP A 215
HIS A 283
GLY A 284
 None
 1.35A 4ey7A-4ypvA:
19.7		 4ey7A-4ypvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 4ypv EST8
(Parvibaculum) 		5 / 11 GLY A  87
SER A 159
TRP A 215
HIS A 283
GLY A 284
 None
 1.39A 4ey7B-4ypvA:
19.5		 4ey7B-4ypvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.07A 4g3rA-4ypvA:
undetectable		 4g3rA-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.05A 4g3rB-4ypvA:
undetectable		 4g3rB-4ypvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.08A 4kkyX-4ypvA:
undetectable		 4kkyX-4ypvA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 5 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.12A 4l49A-4ypvA:
undetectable		 4l49A-4ypvA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 6 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.07A 4l4cA-4ypvA:
undetectable		 4l4cA-4ypvA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 1.05A 4l4gA-4ypvA:
undetectable		 4l4gA-4ypvA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4ypv EST8
(Parvibaculum) 		5 / 12 GLY A 162
ALA A 160
THR A  96
HIS A  97
GLY A  87
 None
 0.86A 4ls7A-4ypvA:
undetectable		 4ls7A-4ypvA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4ypv EST8
(Parvibaculum) 		4 / 6 SER A 103
GLY A  92
ASP A  93
ARG A  35
 None
 0.77A 5cdnC-4ypvA:
undetectable
5cdnD-4ypvA:
3.7		 5cdnC-4ypvA:
23.12
5cdnD-4ypvA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4ypv EST8
(Parvibaculum) 		4 / 6 SER A 103
GLY A  92
ASP A  93
ARG A  35
 None
 0.77A 5cdnT-4ypvA:
undetectable
5cdnU-4ypvA:
3.7		 5cdnT-4ypvA:
23.12
5cdnU-4ypvA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4ypv EST8
(Parvibaculum) 		4 / 5 SER A 159
ALA A 160
HIS A 283
MET A 213
 None
 1.23A 5dzkb-4ypvA:
undetectable
5dzkp-4ypvA:
undetectable		 5dzkb-4ypvA:
22.35
5dzkp-4ypvA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4ypv EST8
(Parvibaculum) 		4 / 6 SER A 159
ALA A 160
HIS A 283
MET A 213
 None
 1.25A 5dzkB-4ypvA:
2.6
5dzkP-4ypvA:
undetectable		 5dzkB-4ypvA:
22.35
5dzkP-4ypvA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4ypv EST8
(Parvibaculum) 		4 / 5 SER A 159
ALA A 160
HIS A 283
MET A 213
 None
 1.23A 5dzkc-4ypvA:
2.0
5dzkq-4ypvA:
undetectable		 5dzkc-4ypvA:
22.35
5dzkq-4ypvA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4ypv EST8
(Parvibaculum) 		4 / 5 SER A 159
ALA A 160
HIS A 283
MET A 213
 None
 1.22A 5dzkf-4ypvA:
2.6
5dzkt-4ypvA:
undetectable		 5dzkf-4ypvA:
22.35
5dzkt-4ypvA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4ypv EST8
(Parvibaculum) 		4 / 6 SER A 159
ALA A 160
HIS A 283
MET A 213
 None
 1.23A 5dzkg-4ypvA:
2.7
5dzku-4ypvA:
undetectable		 5dzkg-4ypvA:
22.35
5dzku-4ypvA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 4ypv EST8
(Parvibaculum) 		4 / 7 VAL A 168
SER A 169
ALA A 172
VAL A 136
 None
 0.49A 5fpdA-4ypvA:
undetectable		 5fpdA-4ypvA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4ypv EST8
(Parvibaculum) 		5 / 10 ALA A 302
LEU A 184
LEU A 185
HIS A  97
LEU A 100
 None
 1.50A 5hyrA-4ypvA:
undetectable		 5hyrA-4ypvA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4ypv EST8
(Parvibaculum) 		4 / 6 GLY A  88
ASP A  42
TYR A  83
TYR A 187
 None
 1.12A 5iwuA-4ypvA:
undetectable		 5iwuA-4ypvA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 4ypv EST8
(Parvibaculum) 		4 / 7 LEU A  81
THR A  96
ASP A  42
LEU A 184
 None
 1.03A 5jq7B-4ypvA:
undetectable		 5jq7B-4ypvA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4ypv EST8
(Parvibaculum) 		5 / 12 ILE A 153
PHE A 104
ALA A 305
LEU A 306
ALA A 108
 None
 1.22A 5oy02-4ypvA:
undetectable		 5oy02-4ypvA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4ypv EST8
(Parvibaculum) 		4 / 7 PHE A 125
TYR A 220
LEU A 164
VAL A 167
 None
 0.98A 5wk9A-4ypvA:
undetectable		 5wk9A-4ypvA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ypv EST8
(Parvibaculum) 		5 / 12 LEU A  94
THR A  96
ASP A 116
LEU A 119
GLY A  86
 None
 1.40A 6aphA-4ypvA:
7.0		 6aphA-4ypvA:
23.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IEY_A_CLMA401_0
(ESTERASE)		 4ypv EST8
(Parvibaculum) 		7 / 11 ILE A  91
HIS A  97
ASP A 158
LEU A 208
HIS A 283
GLY A 284
ALA A  38
 None
 0.50A 6ieyA-4ypvA:
42.8
6ieyB-4ypvA:
42.9		 6ieyA-4ypvA:
42.78
6ieyB-4ypvA:
42.78