SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4yr6 HEAVY CHAIN OF 5G6
(Mus
musculus) 		3 / 3 THR A 117
GLU A 157
HIS A 208
 None
 0.82A 3g1uB-4yr6A:
undetectable		 3g1uB-4yr6A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4yr6 HEAVY CHAIN OF 5G6
(Mus
musculus) 		3 / 3 THR A 119
GLU A 157
HIS A 208
 None
 0.83A 3g1uB-4yr6A:
undetectable		 3g1uB-4yr6A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4yr6 HEAVY CHAIN OF 5G6
(Mus
musculus) 		3 / 3 PRO A  14
LEU A  12
GLN A  16
 None
 0.66A 3hznG-4yr6A:
undetectable
3hznH-4yr6A:
undetectable		 3hznG-4yr6A:
17.98
3hznH-4yr6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 4yr6 HEAVY CHAIN OF 5G6
(Mus
musculus) 		3 / 3 THR A 103
SER A 106
ASP A 110
 None
 0.67A 5kvaA-4yr6A:
undetectable		 5kvaA-4yr6A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 4yr6 HEAVY CHAIN OF 5G6
(Mus
musculus) 		3 / 3 THR A 103
SER A 106
ASP A 110
 None
 0.67A 5kvaB-4yr6A:
undetectable		 5kvaB-4yr6A:
19.38