SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ysw'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BCU_H_PRLH280_0 (ALPHA-THROMBIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 9	ASP A 428 ALA A 337 VAL A 341 GLY A  47 GLY A 144	FAD  A3004 (-3.7A) FAD  A3004 (-3.4A) FAD  A3004 (-4.9A) FES  A3002 (-4.4A) None	1.16A	1bcuH-4yswA: undetectable	1bcuH-4yswA: 10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_N_TRPN81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.93A	1c9sN-4yswA: undetectable 1c9sO-4yswA: undetectable	1c9sN-4yswA: 5.06 1c9sO-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_P_TRPP81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.91A	1c9sP-4yswA: undetectable 1c9sQ-4yswA: undetectable	1c9sP-4yswA: 5.06 1c9sQ-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_V_TRPV81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	GLY A 915 GLY A1006 HIS A 884 ALA A1079 ILE A1007	BCT  A3006 (-3.9A) None None URC  A3007 (-3.4A) None	0.91A	1c9sL-4yswA: undetectable 1c9sV-4yswA: undetectable	1c9sL-4yswA: 5.06 1c9sV-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_A_ADNA601_2 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 5	THR A1066 THR A1044 HIS A 579 HIS A1062	None	1.03A	1d4fA-4yswA: undetectable	1d4fA-4yswA: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_A_ACTA3001_0 (BETA-CARBONIC ANHYDRASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	CYH A 149 GLY A 795 GLY A 796 GLN A 585	FES  A3001 (-2.6A) None None None	0.83A	1ekjA-4yswA: undetectable 1ekjB-4yswA: undetectable	1ekjA-4yswA: 11.25 1ekjB-4yswA: 11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_E_ACTE3005_0 (BETA-CARBONIC ANHYDRASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	CYH A 149 GLY A 795 GLY A 796 GLN A 585	FES  A3001 (-2.6A) None None None	0.89A	1ekjE-4yswA: undetectable 1ekjF-4yswA: undetectable	1ekjE-4yswA: 11.25 1ekjF-4yswA: 11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_F_ACTF3008_0 (BETA-CARBONIC ANHYDRASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLN A 585 CYH A 149 GLY A 795 GLY A 796	None FES  A3001 (-2.6A) None None	0.85A	1ekjE-4yswA: undetectable 1ekjF-4yswA: undetectable	1ekjE-4yswA: 11.25 1ekjF-4yswA: 11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_G_ACTG3002_0 (BETA-CARBONIC ANHYDRASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	CYH A 149 GLY A 795 GLY A 796 GLN A 585	FES  A3001 (-2.6A) None None None	0.87A	1ekjG-4yswA: undetectable 1ekjH-4yswA: undetectable	1ekjG-4yswA: 11.25 1ekjH-4yswA: 11.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FO4_A_SALA3005_1 (XANTHINE DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 9	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.44A	1fo4A-4yswA: 45.7	1fo4A-4yswA: 86.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FO4_B_SALB4005_1 (XANTHINE DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 7	GLU A 802 SER A 876 ARG A 880 PHE A 914 THR A1010 ALA A1078	URC  A3007 (-3.0A) None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A)	0.38A	1fo4B-4yswA: 45.6	1fo4B-4yswA: 86.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_Q_TRPQ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.92A	1gtfQ-4yswA: undetectable 1gtfR-4yswA: undetectable	1gtfQ-4yswA: 5.06 1gtfR-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_S_TRPS81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.92A	1gtfS-4yswA: undetectable 1gtfT-4yswA: undetectable	1gtfS-4yswA: 5.06 1gtfT-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_T_TRPT81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.94A	1gtnT-4yswA: undetectable 1gtnU-4yswA: undetectable	1gtnT-4yswA: 5.06 1gtnU-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_V_TRPV81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	GLY A 915 GLY A1006 HIS A 884 ALA A1079 ILE A1007	BCT  A3006 (-3.9A) None None URC  A3007 (-3.4A) None	0.93A	1gtnL-4yswA: undetectable 1gtnV-4yswA: undetectable	1gtnL-4yswA: 5.06 1gtnV-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JFF_B_TA1B601_1 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	1jffB-4yswA: undetectable	1jffB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JG3_A_ADNA500_1 (PROTEIN-L-ISOASPARTA TE O-METHYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1039 GLY A1041 GLU A1037 ARG A 793 GLY A 795	None	0.96A	1jg3A-4yswA: undetectable	1jg3A-4yswA: 10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JG3_B_ADNB550_1 (PROTEIN-L-ISOASPARTA TE O-METHYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1039 GLY A1041 GLU A1037 ARG A 793 GLY A 795	None	0.94A	1jg3B-4yswA: undetectable	1jg3B-4yswA: 10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_A_NOVA400_1 (DNA GYRASE SUBUNIT B)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	ASP A1026 GLU A1114 ILE A1056 PRO A1057 ILE A1061	None	1.13A	1kijA-4yswA: undetectable	1kijA-4yswA: 15.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1N5X_A_TEIA3006_1 (XANTHINE DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	10 / 12	LEU A 648 ASN A 768 GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 ALA A1078 ALA A1079	None None URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.36A	1n5xA-4yswA: 44.9	1n5xA-4yswA: 86.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1N5X_A_TEIA3006_1 (XANTHINE DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	10 / 12	LEU A 648 LYS A 771 GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 ALA A1078 ALA A1079	None None URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.72A	1n5xA-4yswA: 44.9	1n5xA-4yswA: 86.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1N5X_B_TEIB4006_1 (XANTHINE DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	10 / 12	LEU A 648 ASN A 768 GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 ALA A1078 ALA A1079	None None URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.35A	1n5xB-4yswA: 44.9	1n5xB-4yswA: 86.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1N5X_B_TEIB4006_1 (XANTHINE DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	10 / 12	LEU A 648 LYS A 771 GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 ALA A1078 ALA A1079	None None URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.72A	1n5xB-4yswA: 44.9	1n5xB-4yswA: 86.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_D_BEZD507_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	PHE A 842 ALA A 881 ILE A 900 ILE A 712	None	0.84A	1oniD-4yswA: undetectable 1oniF-4yswA: undetectable	1oniD-4yswA: 8.29 1oniF-4yswA: 8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P93_A_DEXA1999_1 (GLUCOCORTICOID RECEPTOR)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A  30 LEU A  36 GLY A  35 THR A  24 ILE A  77	None	1.46A	1p93A-4yswA: undetectable	1p93A-4yswA: 11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_B_DIFB1701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 9	LEU A1243 LEU A1266 VAL A1179 GLY A1156 SER A1154	None	1.16A	1pxxB-4yswA: undetectable	1pxxB-4yswA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_D_DIFD3701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	LEU A1243 LEU A1266 VAL A1179 GLY A1156 SER A1154	None	1.15A	1pxxD-4yswA: undetectable	1pxxD-4yswA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_B_FUAB703_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	SER A 367 LEU A 311 VAL A 307 PHE A 298 THR A 323	None	1.30A	1q23B-4yswA: undetectable	1q23B-4yswA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_C_FUAC701_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	PHE A 417 SER A 367 LEU A 311 VAL A 307 PHE A 298	None	1.34A	1q23C-4yswA: undetectable	1q23C-4yswA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_F_FUAF704_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	SER A 367 LEU A 311 VAL A 307 PHE A 298 THR A 323	None	1.36A	1q23F-4yswA: undetectable	1q23F-4yswA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RU9_H_ACTH611_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	LEU A 520 TRP A 993 LEU A1167 PHE A1312	None	0.74A	1ru9H-4yswA: undetectable 1ru9L-4yswA: undetectable	1ru9H-4yswA: 11.02 1ru9L-4yswA: 9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RUK_L_ACTL611_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	LEU A 520 TRP A 993 LEU A1167 PHE A1312	None	0.72A	1rukH-4yswA: undetectable 1rukL-4yswA: undetectable	1rukH-4yswA: 11.02 1rukL-4yswA: 9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_O_TRPO81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.94A	1utdO-4yswA: undetectable 1utdP-4yswA: undetectable	1utdO-4yswA: 5.06 1utdP-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_P_TRPP81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.93A	1utdP-4yswA: undetectable 1utdQ-4yswA: undetectable	1utdP-4yswA: 5.06 1utdQ-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_S_TRPS81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.92A	1utdS-4yswA: undetectable 1utdT-4yswA: undetectable	1utdS-4yswA: 5.06 1utdT-4yswA: 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_U_TRPU81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	GLY A1006 HIS A 884 ALA A1079 ILE A1007 GLY A 915	None None URC  A3007 (-3.4A) None BCT  A3006 (-3.9A)	0.95A	1utdU-4yswA: undetectable 1utdV-4yswA: undetectable	1utdU-4yswA: 5.06 1utdV-4yswA: 5.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1WYG_A_SALA4005_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	10 / 10	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 PHE A1009 THR A1010 ALA A1078 ALA A1079 GLU A1261	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-4.6A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A) URC  A3007 (-2.9A)	0.37A	1wygA-4yswA: 45.9	1wygA-4yswA: 99.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_A_RBFA300_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	GLY A 732 SER A 731 TRP A 926 ILE A 922 ALA A 844	None	1.35A	2a58A-4yswA: 2.2 2a58E-4yswA: 2.1	2a58A-4yswA: 8.61 2a58E-4yswA: 8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_D_RBFD303_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	ILE A 922 ALA A 844 GLY A 732 SER A 731 TRP A 926	None	1.35A	2a58C-4yswA: undetectable 2a58D-4yswA: 2.1	2a58C-4yswA: 8.61 2a58D-4yswA: 8.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2E1Q_A_SALA2006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 6	ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.17A	2e1qA-4yswA: 46.1	2e1qA-4yswA: 90.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2E1Q_B_SALB3006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 4	ARG A 880 PHE A 914 THR A1010 ALA A1079	URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.15A	2e1qB-4yswA: 46.1	2e1qB-4yswA: 90.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2E1Q_C_SALC4006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 6	ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.24A	2e1qC-4yswA: 45.9	2e1qC-4yswA: 90.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2E1Q_D_SALD5006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 5	ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.21A	2e1qD-4yswA: 46.1	2e1qD-4yswA: 90.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FB2_B_SAMB501_0 (MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	THR A 381 THR A 372 SER A 405 VAL A 290	None	1.22A	2fb2B-4yswA: undetectable	2fb2B-4yswA: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HXF_B_TA1B601_1 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	2hxfB-4yswA: undetectable	2hxfB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HXH_B_TA1B601_1 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	2hxhB-4yswA: undetectable	2hxhB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P4N_B_TA1B601_1 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	2p4nB-4yswA: undetectable	2p4nB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6H_A_CXXA802_1 (TRANSPORTER)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	ILE A 104 SER A 107 ILE A 138 PHE A 142	None	0.98A	2q6hA-4yswA: undetectable	2q6hA-4yswA: 17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	PRO A 303 SER A 305 VAL A 258 GLY A 259	None None FAD  A3004 (-3.9A) FAD  A3004 (-3.2A)	0.96A	2qd3A-4yswA: undetectable	2qd3A-4yswA: 13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEU_A_ACTA142_0 (PUTATIVE CARBOXYMUCONOLACTONE DECARBOXYLASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 5	GLU A 407 PRO A 409 ILE A 408 LYS A 370	None	1.09A	2qeuA-4yswA: 2.1 2qeuC-4yswA: 0.9	2qeuA-4yswA: 7.38 2qeuC-4yswA: 7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_P_ASDP1224_1 (GLUTATHIONE S-TRANSFERASE A3)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	LEU A1014 LEU A1011 ALA A1079 ALA A 910	None None URC  A3007 (-3.4A) URC  A3007 (-4.0A)	0.73A	2vcvP-4yswA: undetectable	2vcvP-4yswA: 10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W8Y_B_NDRB1000_0 (PROGESTERONE RECEPTOR)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A 493 LEU A 510 LEU A 453 MET A 437 CYH A 486	None	1.30A	2w8yB-4yswA: undetectable	2w8yB-4yswA: 12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WBE_B_TA1B1439_1 (TUBULIN BETA-2B CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	2wbeB-4yswA: undetectable	2wbeB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WUZ_A_TPFA1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE , PUTATIVE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	ALA A 811 ALA A 815 THR A 819 LEU A 603 VAL A 632	None	1.28A	2wuzA-4yswA: undetectable	2wuzA-4yswA: 15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WUZ_B_TPFB1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE , PUTATIVE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	ALA A 811 ALA A 815 THR A 819 LEU A 603 VAL A 632	None	1.28A	2wuzB-4yswA: undetectable	2wuzB-4yswA: 15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WX2_A_TPFA1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	PHE A 655 ALA A 811 ALA A 815 THR A 819	None	0.84A	2wx2A-4yswA: undetectable	2wx2A-4yswA: 15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_A_QPSA1060_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	THR A 261 VAL A 344 SER A  69 SER A 122 GLY A  46	FAD  A3004 (-2.9A) None None None FES  A3002 ( 3.3A)	1.14A	2x2iA-4yswA: undetectable	2x2iA-4yswA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_C_QPSC1060_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	THR A 261 VAL A 344 SER A  69 SER A 122 GLY A  46	FAD  A3004 (-2.9A) None None None FES  A3002 ( 3.3A)	1.18A	2x2iC-4yswA: undetectable	2x2iC-4yswA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_D_QPSD1060_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	THR A 261 VAL A 344 SER A  69 SER A 122 GLY A  46	FAD  A3004 (-2.9A) None None None FES  A3002 ( 3.3A)	1.21A	2x2iD-4yswA: undetectable	2x2iD-4yswA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_B_TC9B1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	SER A1067 TYR A 592 THR A1077 GLN A1040 SER A 765	None	1.47A	2xytB-4yswA: 0.0 2xytC-4yswA: 0.0 2xytG-4yswA: 0.0	2xytB-4yswA: 10.69 2xytC-4yswA: 10.69 2xytG-4yswA: 10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6R_B_CTCB1385_0 (TETX2 PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLN A 918 PHE A 914 GLY A 915 GLY A 800	BCT  A3006 (-3.0A) URC  A3007 ( 3.4A) BCT  A3006 (-3.9A) None	0.81A	2y6rB-4yswA: undetectable	2y6rB-4yswA: 14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A1031 THR A1032 ALA A1093 THR A1096 ILE A1097	None	1.05A	3a35A-4yswA: undetectable	3a35A-4yswA: 8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_B_RBFB191_1 (LUMAZINE PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A1031 THR A1032 ALA A1093 THR A1096 ILE A1097	None	1.05A	3a35B-4yswA: undetectable	3a35B-4yswA: 8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A1031 THR A1032 ALA A1093 THR A1096 ILE A1097	None	1.06A	3a3bA-4yswA: undetectable	3a3bA-4yswA: 8.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AX7_B_SALB1336_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 9	GLU A 802 SER A 876 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1078 ALA A1079	URC  A3007 (-3.0A) None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.32A	3ax7B-4yswA: 44.3	3ax7B-4yswA: 86.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AX9_B_SALB1340_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 8	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 ALA A1078 ALA A1079	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.32A	3ax9B-4yswA: 44.0	3ax9B-4yswA: 86.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCO_B_TA1B601_1 (BOVINE BETA TUBULIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	3dcoB-4yswA: undetectable	3dcoB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EDL_B_TA1B601_1 (BETA TUBULIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.23A	3edlB-4yswA: undetectable	3edlB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H52_C_486C4_2 (GLUCOCORTICOID RECEPTOR)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	MET A 927 CYH A 999 PRO A1002	None	0.89A	3h52C-4yswA: undetectable	3h52C-4yswA: 11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I5U_A_SAMA401_0 (O-METHYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	MET A 833 GLY A 838 GLY A 837 LEU A 905 PRO A 906	None None None None GOL  A3008 ( 4.7A)	1.09A	3i5uA-4yswA: undetectable	3i5uA-4yswA: 14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I5U_B_SAMB401_0 (O-METHYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	MET A 833 GLY A 838 GLY A 837 LEU A 905 PRO A 906	None None None None GOL  A3008 ( 4.7A)	1.07A	3i5uB-4yswA: undetectable	3i5uB-4yswA: 14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IZ0_B_TA1B820_1 (BETA TUBULIN, CHAIN B FROM PDB 1JFF)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None None	1.22A	3iz0B-4yswA: undetectable	3iz0B-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1102_0 (STRUCTURAL PROTEIN VP3)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 12	ILE A1253 GLY A1087 GLY A1089 ALA A1019 ALA A1050 VAL A1049	None	1.38A	3jb2A-4yswA: undetectable	3jb2A-4yswA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1102_0 (STRUCTURAL PROTEIN VP3)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	ILE A1253 GLY A1087 GLY A1089 ALA A1093 VAL A1049	None	1.01A	3jb2A-4yswA: undetectable	3jb2A-4yswA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB3_A_SAMA1102_0 (STRUCTURAL PROTEIN VP3)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	ILE A1253 GLY A1087 ALA A1019 ALA A1050 VAL A1049	None	0.76A	3jb3A-4yswA: undetectable	3jb3A-4yswA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KKZ_A_SAMA301_0 (UNCHARACTERIZED PROTEIN Q5LES9)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	GLN A 767 GLY A 795 GLY A 797 LEU A 744 GLU A1037	None None None FES  A3001 ( 4.0A) None	1.02A	3kkzA-4yswA: undetectable	3kkzA-4yswA: 11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_D_TFPD201_1 (PROTEIN S100-A4)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLY A 588 CYH A  48 CYH A 147 PHE A 798	None FES  A3002 (-2.2A) FES  A3001 (-2.3A) None	1.05A	3ko0D-4yswA: undetectable 3ko0E-4yswA: undetectable	3ko0D-4yswA: 6.15 3ko0E-4yswA: 6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_J_TFPJ201_1 (PROTEIN S100-A4)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLY A 588 CYH A  48 CYH A 147 PHE A 798	None FES  A3002 (-2.2A) FES  A3001 (-2.3A) None	1.05A	3ko0B-4yswA: undetectable 3ko0J-4yswA: undetectable	3ko0B-4yswA: 6.15 3ko0J-4yswA: 6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_D_TPFD490_1 (STEROL 14-ALPHA DEMETHYLASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	MET A 779 ALA A 811 ALA A 815 THR A 819	None	1.07A	3l4dD-4yswA: undetectable	3l4dD-4yswA: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_D_TPFD490_1 (STEROL 14-ALPHA DEMETHYLASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	PHE A 655 ALA A 811 ALA A 815 THR A 819	None	0.80A	3l4dD-4yswA: undetectable	3l4dD-4yswA: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NNE_G_ACTG601_0 (CHOLINE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	ALA A1273 ILE A1270 HIS A1171 ASN A1173	None	1.14A	3nneG-4yswA: undetectable	3nneG-4yswA: 17.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 6	GLU A 802 ARG A 880 PHE A 914 THR A1010 ALA A1078 ALA A1079	URC  A3007 (-3.0A) URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) URC  A3007 (-3.5A) URC  A3007 (-3.4A)	0.35A	3ns1C-4yswA: 58.8	3ns1C-4yswA: 59.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SGL_A_SAMA692_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	GLY A1089 GLY A1131 THR A1130 LEU A1020 GLY A1017	None	1.06A	3sglA-4yswA: undetectable	3sglA-4yswA: 20.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UNA_A_SALA1340_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 9	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.32A	3unaA-4yswA: 45.8	3unaA-4yswA: 86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UNA_B_SALB1340_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 9	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.30A	3unaB-4yswA: 45.7	3unaB-4yswA: 86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UNC_A_SALA1338_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 9	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.34A	3uncA-4yswA: 46.2	3uncA-4yswA: 86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UNC_B_SALB1338_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	8 / 9	GLU A 802 LEU A 873 SER A 876 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) None None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.35A	3uncB-4yswA: 46.0	3uncB-4yswA: 86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UNI_A_SALA1344_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	6 / 7	GLU A 802 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.36A	3uniA-4yswA: 45.4	3uniA-4yswA: 86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UNI_B_SALB1345_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	7 / 8	GLU A 802 LEU A 873 ARG A 880 PHE A 914 THR A1010 LEU A1014 ALA A1079	URC  A3007 (-3.0A) None URC  A3007 (-3.7A) URC  A3007 ( 3.4A) URC  A3007 (-3.5A) None URC  A3007 (-3.4A)	0.36A	3uniB-4yswA: 40.0	3uniB-4yswA: 86.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_B_MIYB2001_1 (TETX2 PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLN A 918 PHE A 914 GLY A 915 GLY A 800	BCT  A3006 (-3.0A) URC  A3007 ( 3.4A) BCT  A3006 (-3.9A) None	0.75A	3v3nB-4yswA: undetectable	3v3nB-4yswA: 13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_C_MIYC2001_1 (TETX2 PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLN A 918 PHE A 914 GLY A 915 GLY A 800	BCT  A3006 (-3.0A) URC  A3007 ( 3.4A) BCT  A3006 (-3.9A) None	0.74A	3v3nC-4yswA: undetectable	3v3nC-4yswA: 13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_B_ACTB1002_0 (PUTATIVE OXIDOREDUCTASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 5	GLY A1183 VAL A1182 ASP A1181 THR A 963	None	1.23A	3vqrB-4yswA: undetectable	3vqrB-4yswA: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE506_1 (HEMOLYTIC LECTIN CEL-III)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	ASN A1249 CYH A1247 GLY A1183 ASP A1181	None	1.32A	3w9tE-4yswA: undetectable	3w9tE-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	GLY A 144 ALA A  50 GLY A  49 CYH A  43 CYH A  51	None FES  A3002 ( 4.8A) FES  A3002 (-3.9A) FES  A3002 (-2.3A) FES  A3002 (-2.2A)	1.13A	4c5lC-4yswA: undetectable	4c5lC-4yswA: 11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E47_C_SAMC800_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	ALA A 613 GLY A1217 GLY A 868 ASN A 908 HIS A 665	None None None None GOL  A3008 (-3.9A)	1.27A	4e47C-4yswA: undetectable	4e47C-4yswA: 12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_A_CQAA302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	GLU A 569 GLU A 570 GLY A 574 ARG A 575	None	1.03A	4fgzA-4yswA: undetectable	4fgzA-4yswA: 11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FJP_A_NPSA711_1 (LACTOTRANSFERRIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	THR A 870 GLY A 868 PRO A 906 GLY A 664	GOL  A3008 (-4.8A) None GOL  A3008 ( 4.7A) None	0.90A	4fjpA-4yswA: undetectable	4fjpA-4yswA: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	ASN A 988 GLU A 985 GLU A 983 GLU A1161	None	1.35A	4mj8C-4yswA: 1.8	4mj8C-4yswA: 8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_C_IPHC101_0 (INSULIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	HIS A 817 ALA A 815 LEU A 635 VAL A 776 LEU A 780	None	1.11A	4p65C-4yswA: undetectable 4p65D-4yswA: undetectable 4p65J-4yswA: undetectable 4p65L-4yswA: undetectable	4p65C-4yswA: 1.48 4p65D-4yswA: 2.17 4p65J-4yswA: 2.17 4p65L-4yswA: 2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_K_IPHK101_0 (INSULIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A 635 VAL A 776 LEU A 780 HIS A 817 ALA A 815	None	1.06A	4p65F-4yswA: undetectable 4p65H-4yswA: undetectable 4p65K-4yswA: undetectable 4p65L-4yswA: undetectable	4p65F-4yswA: 2.17 4p65H-4yswA: 2.17 4p65K-4yswA: 1.48 4p65L-4yswA: 2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	GLU A1065 THR A1066 THR A1044 HIS A 579	None	1.09A	4pfjA-4yswA: undetectable	4pfjA-4yswA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	GLU A1065 THR A1066 THR A1044 HIS A 579	None	0.97A	4pfjB-4yswA: undetectable	4pfjB-4yswA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A1098 LEU A1031 ALA A1019 ALA A1050 GLY A1131	None	1.02A	4rn6B-4yswA: undetectable	4rn6B-4yswA: 12.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UHX_A_LZUA3008_1 (ALDEHYDE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 8	ASP A 571 SER A1051 ARG A1052 PRO A1057 TRP A1116	None	0.69A	4uhxA-4yswA: 42.2	4uhxA-4yswA: 49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UHX_A_LZUA3008_1 (ALDEHYDE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 8	ASP A 571 SER A1051 PRO A1057 TRP A1113 TRP A1116	None	1.10A	4uhxA-4yswA: 42.2	4uhxA-4yswA: 49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UHX_A_LZUA3008_1 (ALDEHYDE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLU A 570 ASP A 571 SER A1051 ARG A1052	None	1.18A	4uhxA-4yswA: 42.2	4uhxA-4yswA: 49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UHX_A_RTZA3009_1 (ALDEHYDE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	ASP A 571 SER A1051 ARG A1052 PRO A1057	None	0.70A	4uhxA-4yswA: 42.2	4uhxA-4yswA: 49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UHX_A_RTZA3009_1 (ALDEHYDE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	ASP A 571 SER A1051 PRO A1057 TRP A1113	None	1.02A	4uhxA-4yswA: 42.2	4uhxA-4yswA: 49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UHX_A_RTZA3009_1 (ALDEHYDE OXIDASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLU A 570 ASP A 571 SER A1051 ARG A1052	None	1.18A	4uhxA-4yswA: 42.2	4uhxA-4yswA: 49.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	PHE A1005 ALA A1081 ASP A1084 GLY A 913 SER A1154	None	1.22A	4xnxA-4yswA: undetectable	4xnxA-4yswA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B6I_B_ADNB302_1 (FLUORINASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	THR A1003 TYR A1155 THR A 963 SER A1154	None	1.48A	5b6iB-4yswA: undetectable	5b6iB-4yswA: 13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B8I_C_FK5C201_1 (SERINE/THREONINE-PRO TEIN PHOSPHATASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	LEU A 964 PRO A1263 PHE A1005 GLU A1261	None None None URC  A3007 (-2.9A)	1.28A	5b8iA-4yswA: undetectable	5b8iA-4yswA: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_A_PAUA602_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	GLY A 457 GLY A 501 TYR A 392 ALA A 459	NAI  A3005 (-3.3A) NAI  A3005 (-3.3A) NAI  A3005 (-4.5A) NAI  A3005 (-4.8A)	0.71A	5e26A-4yswA: undetectable 5e26B-4yswA: undetectable	5e26A-4yswA: 14.13 5e26B-4yswA: 14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_B_PAUB601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	TYR A 392 ALA A 459 GLY A 457 GLY A 501	NAI  A3005 (-4.5A) NAI  A3005 (-4.8A) NAI  A3005 (-3.3A) NAI  A3005 (-3.3A)	0.73A	5e26A-4yswA: undetectable 5e26B-4yswA: undetectable	5e26A-4yswA: 14.13 5e26B-4yswA: 14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_C_PAUC602_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	GLY A 457 GLY A 501 TYR A 392 ALA A 459	NAI  A3005 (-3.3A) NAI  A3005 (-3.3A) NAI  A3005 (-4.5A) NAI  A3005 (-4.8A)	0.67A	5e26C-4yswA: undetectable 5e26D-4yswA: undetectable	5e26C-4yswA: 14.13 5e26D-4yswA: 14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_D_PAUD601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	TYR A 392 ALA A 459 GLY A 457 GLY A 501	NAI  A3005 (-4.5A) NAI  A3005 (-4.8A) NAI  A3005 (-3.3A) NAI  A3005 (-3.3A)	0.67A	5e26C-4yswA: undetectable 5e26D-4yswA: undetectable	5e26C-4yswA: 14.13 5e26D-4yswA: 14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F9Z_A_HFGA702_0 (AMINOACYL-TRNA SYNTHETASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A1243 GLY A1193 VAL A1241 SER A1080 GLY A 913	None	1.31A	5f9zA-4yswA: undetectable	5f9zA-4yswA: 17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNW_B_TA1B902_1 (TUBULIN BETA-2B CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409	None FAD  A3004 (-4.7A) None None None	1.03A	5hnwB-4yswA: undetectable	5hnwB-4yswA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNX_B_TA1B902_1 (TUBULIN BETA-2B CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	GLU A 929 SER A 928 PHE A1271 THR A1300 ARG A1305	None	1.35A	5hnxB-4yswA: undetectable	5hnxB-4yswA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNY_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 PRO A 409	None FAD  A3004 (-4.7A) None None None	1.09A	5hnyB-4yswA: undetectable	5hnyB-4yswA: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNZ_B_TA1B902_1 (TUBULIN BETA-2B CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	GLU A 929 SER A 928 PHE A1271 THR A1300 ARG A1305	None	1.36A	5hnzB-4yswA: undetectable	5hnzB-4yswA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKQ_A_JMSA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	VAL A 789 SER A 805 MET A 826	None	0.91A	5ikqA-4yswA: undetectable	5ikqA-4yswA: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JO9_A_SORA302_0 (RIBITOL 2-DEHYDROGENASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	LEU A  34 THR A  87 GLU A  89 GLY A  35 LEU A  30	None	1.39A	5jo9A-4yswA: undetectable	5jo9A-4yswA: 11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KF8_A_GCSA404_1 (PREDICTED ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLU A 231 GLY A 630 PRO A 629 ASP A 673	None	1.03A	5kf8A-4yswA: 0.0	5kf8A-4yswA: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KGP_A_GCSA407_1 (PREDICTED ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLU A 231 GLY A 630 PRO A 629 ASP A 673	None	1.07A	5kgpA-4yswA: 2.0	5kgpA-4yswA: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KGP_B_GCSB405_1 (PREDICTED ACETYLTRANSFERASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	GLU A 231 GLY A 630 PRO A 629 ASP A 673	None	1.06A	5kgpB-4yswA: undetectable	5kgpB-4yswA: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR2_C_ROCC101_1 (PROTEASE PR5-SQV)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 9	ASN A 644 ALA A 637 ASP A 639 GLY A 668 THR A 810	None	1.18A	5kr2C-4yswA: undetectable	5kr2C-4yswA: 6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OGC_B_TA1B601_1 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	VAL A 329 LEU A 403 THR A 372 PRO A 409 GLY A 295	None FAD  A3004 (-4.7A) None None None	1.27A	5ogcB-4yswA: undetectable	5ogcB-4yswA: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TJZ_A_BEZA302_0 (4-HYDROXY-TETRAHYDRO DIPICOLINATE REDUCTASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	MET A 927 GLU A 939 ARG A 942	None	1.06A	5tjzA-4yswA: undetectable	5tjzA-4yswA: 11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUD_A_ERMA2001_2 (5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 7	THR A 116 VAL A1200 GLN A 739 GLU A 740	None	1.14A	5tudA-4yswA: undetectable	5tudA-4yswA: 16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	GLU A 740 HIS A 741 ARG A 839	None None BCT  A3006 (-4.0A)	0.93A	5uunA-4yswA: undetectable	5uunA-4yswA: 12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WM2_A_ACTA605_0 (SALICYLATE-AMP LIGASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	THR A1313 THR A 509 ARG A1305	None	1.01A	5wm2A-4yswA: undetectable	5wm2A-4yswA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X24_A_LSNA502_1 (CYTOCHROME P450 2C9)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	ALA A 105 VAL A 120 MET A 121 VAL A  88 GLY A  92	None	1.21A	5x24A-4yswA: undetectable	5x24A-4yswA: 17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_A_ADNA506_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	TRP A 993 LEU A 520 GLU A 479 LEU A 482	None	1.20A	5xooA-4yswA: undetectable	5xooA-4yswA: 5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA411_0 (UNCHARACTERIZED PROTEIN KDOO)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	LYS A1172 LEU A1174 ARG A 996	None	0.82A	5yw0A-4yswA: undetectable	5yw0A-4yswA: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA412_0 (UNCHARACTERIZED PROTEIN KDOO)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	3 / 3	LYS A 995 ASN A 991 SER A 544	None	1.27A	5yw0A-4yswA: undetectable	5yw0A-4yswA: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_A_SAMA401_0 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	ALA A1189 GLY A1041 SER A 107 PRO A 576 PHE A 560	None	1.30A	5zvgA-4yswA: undetectable	5zvgA-4yswA: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_B_SAMB401_0 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	ALA A1189 GLY A1041 SER A 107 PRO A 576 PHE A 560	None	1.28A	5zvgB-4yswA: undetectable	5zvgB-4yswA: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZWR_B_9KLB402_0 (EST-Y29)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	SER A 122 PHE A1232 ILE A 155 LEU A 156 ALA A 141	None	1.07A	5zwrB-4yswA: undetectable	5zwrB-4yswA: 15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AY4_A_TPFA506_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	MET A 779 ALA A 811 ALA A 815 THR A 819 CYH A 633	None	1.23A	6ay4A-4yswA: undetectable	6ay4A-4yswA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B0C_D_TA1D502_1 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 12	VAL A 329 LEU A 403 LEU A 371 THR A 372 GLY A 295	None FAD  A3004 (-4.7A) None None None	0.86A	6b0cD-4yswA: undetectable	6b0cD-4yswA: 5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C06_D_FI8D1404_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 8	ILE A 119 THR A 116 THR A  39 GLU A  89	None	1.09A	6c06C-4yswA: undetectable	6c06C-4yswA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	4 / 6	LEU A 493 LEU A 466 THR A 462 ARG A 383	None	0.96A	6ew0G-4yswA: undetectable	6ew0G-4yswA: 5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_I_PCFI101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 11	SER A1269 VAL A1195 GLY A1260 SER A1080 ALA A1081	None	1.16A	6hu9A-4yswA: undetectable 6hu9E-4yswA: 1.3 6hu9I-4yswA: undetectable	6hu9A-4yswA: 15.73 6hu9E-4yswA: 9.34 6hu9I-4yswA: 4.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	4ysw	XANTHINE DEHYDROGENASE/OXIDAS E (Rattus norvegicus)	5 / 10	SER A1269 VAL A1195 GLY A1260 SER A1080 ALA A1081	None	1.14A	6hu9L-4yswA: undetectable 6hu9P-4yswA: undetectable 6hu9T-4yswA: undetectable	6hu9L-4yswA: 15.73 6hu9P-4yswA: 9.34 6hu9T-4yswA: 4.22