SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 4yuf CORB
(Corallococcus
coralloides) 		4 / 4 ILE A 262
MET A 331
VAL A 175
GLY A 317
 None
 1.31A 1e06B-4yufA:
undetectable		 1e06B-4yufA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 4yuf CORB
(Corallococcus
coralloides) 		4 / 7 ALA A 119
GLY A  88
ILE A 294
PRO A 299
 None
 0.85A 2fxdB-4yufA:
undetectable		 2fxdB-4yufA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4yuf CORB
(Corallococcus
coralloides) 		3 / 3 SER A 189
HIS A 264
ASP A 149
 None
 0.82A 2oxtA-4yufA:
undetectable		 2oxtA-4yufA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4yuf CORB
(Corallococcus
coralloides) 		4 / 5 SER A  27
PRO A  38
GLY A  39
TRP A  40
 None
 1.44A 2y7kB-4yufA:
undetectable		 2y7kB-4yufA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4yuf CORB
(Corallococcus
coralloides) 		4 / 6 SER A  27
PRO A  38
GLY A  39
TRP A  40
 None
 1.33A 2y7pA-4yufA:
undetectable		 2y7pA-4yufA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 10 ALA A 119
VAL A 329
GLY A 295
ILE A 294
THR A 322
 None
 1.17A 3el5A-4yufA:
undetectable		 3el5A-4yufA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 12 GLY A 295
PRO A 299
ALA A 171
ALA A 170
SER A 324
 None
 1.25A 3mteA-4yufA:
undetectable		 3mteA-4yufA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 12 GLY A 295
GLY A  88
ALA A 170
ALA A 171
LEU A 122
 None
 1.01A 3p2kA-4yufA:
undetectable		 3p2kA-4yufA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 12 GLY A 295
GLY A  88
ALA A 170
ALA A 171
LEU A 122
 None
 1.02A 3p2kC-4yufA:
undetectable		 3p2kC-4yufA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 12 GLY A 295
GLY A  88
ALA A 170
ALA A 171
LEU A 122
 None
 1.06A 3p2kD-4yufA:
undetectable		 3p2kD-4yufA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 9 GLY A 323
GLY A 321
CYH A 121
LEU A 122
GLN A 265
 None
 1.13A 4l8wG-4yufA:
undetectable		 4l8wG-4yufA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 9 LEU A 231
GLY A 235
VAL A 326
SER A 327
LEU A 122
 None
 1.22A 4qd3A-4yufA:
undetectable		 4qd3A-4yufA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 12 GLY A  62
ALA A  63
ILE A 150
SER A 151
PRO A  21
 None
 1.12A 4rtpA-4yufA:
undetectable		 4rtpA-4yufA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 9 VAL A 175
LEU A 128
ALA A 127
PHE A 124
ILE A  13
 None
 0.94A 5om2A-4yufA:
undetectable
5om2B-4yufA:
undetectable		 5om2A-4yufA:
13.77
5om2B-4yufA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 12 PHE A 333
TYR A 273
LEU A 274
ILE A 262
MET A 298
 None
 1.14A 5y2tB-4yufA:
undetectable		 5y2tB-4yufA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 4yuf CORB
(Corallococcus
coralloides) 		5 / 11 TYR A 335
MET A 331
LEU A 319
GLY A 309
LEU A 128
 None
 1.11A 6euqA-4yufA:
undetectable		 6euqA-4yufA:
20.88