SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EJ0_A_SAMA301_1 (FTSJ)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	3 / 3	ASP A 118 ASP A 149 ASP A 168	S4M A 301 (-3.0A) S4M A 301 (-3.9A) S4M A 301 (-3.1A)	0.79A	1ej0A-4yv2A: 11.4	1ej0A-4yv2A: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_C_ACTC3007_0 (BETA-CARBONIC ANHYDRASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 6	VAL A 234 GLY A 243 GLN A 201 TYR A 73	None None None S4M A 301 (-4.4A)	1.25A	1ekjC-4yv2A: undetectable 1ekjD-4yv2A: undetectable	1ekjC-4yv2A: 22.22 1ekjD-4yv2A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N2X_B_SAMB402_0 (S-ADENOSYL-METHYLTRA NSFERASE MRAW)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLY A 97 GLY A 99 GLY A 100 ASP A 120 VAL A 123	S4M A 301 ( 4.5A) None None None S4M A 301 (-4.3A)	0.68A	1n2xB-4yv2A: 13.4	1n2xB-4yv2A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QAO_A_SAMA245_0 (ERMC' METHYLTRANSFERASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLY A 95 GLY A 97 ILE A 119 ASP A 120 ASP A 149	S4M A 301 (-3.5A) S4M A 301 ( 4.5A) S4M A 301 (-3.9A) None S4M A 301 (-3.9A)	0.71A	1qaoA-4yv2A: 9.2	1qaoA-4yv2A: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQ5_B_PAUB6003_0 (PANTOTHENATE KINASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 10	ASP A 98 GLY A 95 HIS A 74 LEU A 116 ILE A 167	S4M A 301 (-3.1A) S4M A 301 (-3.5A) S4M A 301 (-4.0A) None None	1.24A	1sq5B-4yv2A: 1.0	1sq5B-4yv2A: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_0 (SUN PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	6 / 12	GLY A 99 GLY A 100 ILE A 119 ASP A 120 ASP A 149 GLY A 150	None None S4M A 301 (-3.9A) None S4M A 301 (-3.9A) S4M A 301 (-3.6A)	0.47A	1sqfA-4yv2A: 9.5	1sqfA-4yv2A: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_A_CHDA130_1 (FATTY ACID-BINDING PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	3 / 3	TYR A 162 ARG A 155 GLN A 156	None	0.93A	1tw4A-4yv2A: undetectable	1tw4A-4yv2A: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QB4_A_DSMA802_1 (TRANSPORTER)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 7	ILE A 197 ARG A 220 PHE A 224 ILE A 219	None	1.00A	2qb4A-4yv2A: undetectable	2qb4A-4yv2A: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UZ2_A_ACTA1123_0 (XENAVIDIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 7	ASN A 200 LEU A 245 TYR A 185 VAL A 227	None	1.11A	2uz2A-4yv2A: undetectable	2uz2A-4yv2A: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7W_C_SALC1300_1 (LYSR-TYPE REGULATORY PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 7	THR A 169 ILE A 94 GLY A 95 ILE A 119	S4M A 301 (-4.7A) None S4M A 301 (-3.5A) S4M A 301 (-3.9A)	0.70A	2y7wC-4yv2A: undetectable	2y7wC-4yv2A: 19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_A_SPMA501_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	8 / 12	GLN A 64 TYR A 73 HIS A 74 ASP A 98 ASP A 168 GLN A 201 TYR A 237 PRO A 238	S4M A 301 (-4.2A) S4M A 301 (-4.4A) S4M A 301 (-4.0A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None None	0.76A	3b7pA-4yv2A: 38.0	3b7pA-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_A_SPMA501_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	8 / 12	GLN A 64 TYR A 73 HIS A 74 ASP A 98 ASP A 168 TYR A 237 PRO A 238 ILE A 242	S4M A 301 (-4.2A) S4M A 301 (-4.4A) S4M A 301 (-4.0A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None None	0.57A	3b7pA-4yv2A: 38.0	3b7pA-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_A_SPMA501_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLN A 201 HIS A 74 ASP A 168 TYR A 237 PRO A 238	None S4M A 301 (-4.0A) S4M A 301 (-3.1A) None None	1.33A	3b7pA-4yv2A: 38.0	3b7pA-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_B_SPMB502_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	8 / 12	GLN A 64 TYR A 73 HIS A 74 ASP A 98 ASP A 168 GLN A 201 TYR A 237 PRO A 238	S4M A 301 (-4.2A) S4M A 301 (-4.4A) S4M A 301 (-4.0A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None None	0.76A	3b7pB-4yv2A: 38.4	3b7pB-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_B_SPMB502_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	8 / 12	GLN A 64 TYR A 73 HIS A 74 ASP A 98 ASP A 168 TYR A 237 PRO A 238 ILE A 242	S4M A 301 (-4.2A) S4M A 301 (-4.4A) S4M A 301 (-4.0A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None None	0.59A	3b7pB-4yv2A: 38.4	3b7pB-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_B_SPMB502_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLN A 201 HIS A 74 ASP A 168 TYR A 237 PRO A 238	None S4M A 301 (-4.0A) S4M A 301 (-3.1A) None None	1.40A	3b7pB-4yv2A: 38.4	3b7pB-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_C_SPMC503_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	10 / 12	GLN A 64 TYR A 73 HIS A 74 ASP A 98 ASP A 168 GLU A 203 SER A 204 TYR A 237 PRO A 238 ILE A 242	S4M A 301 (-4.2A) S4M A 301 (-4.4A) S4M A 301 (-4.0A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None None None None	0.63A	3b7pC-4yv2A: 38.3	3b7pC-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3B7P_C_SPMC503_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLN A 201 HIS A 74 ASP A 168 TYR A 237 PRO A 238	None S4M A 301 (-4.0A) S4M A 301 (-3.1A) None None	1.29A	3b7pC-4yv2A: 38.3	3b7pC-4yv2A: 42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_A_SAMA501_0 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	6 / 12	GLN A 40 GLY A 96 ASP A 120 VAL A 123 THR A 169 GLN A 201	S4M A 301 (-3.4A) S4M A 301 ( 4.6A) None S4M A 301 (-4.3A) S4M A 301 (-4.7A) None	1.09A	3bwcA-4yv2A: 46.7	3bwcA-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_A_SAMA501_0 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	12 / 12	GLN A 40 TYR A 73 HIS A 74 ILE A 94 GLY A 95 ILE A 119 ASP A 120 VAL A 123 ASP A 149 GLY A 150 THR A 169 GLN A 201	S4M A 301 (-3.4A) S4M A 301 (-4.4A) S4M A 301 (-4.0A) None S4M A 301 (-3.5A) S4M A 301 (-3.9A) None S4M A 301 (-4.3A) S4M A 301 (-3.9A) S4M A 301 (-3.6A) S4M A 301 (-4.7A) None	0.49A	3bwcA-4yv2A: 46.7	3bwcA-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_A_SAMA501_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 4	LEU A 59 GLN A 64 ASP A 118 ASP A 168	None S4M A 301 (-4.2A) S4M A 301 (-3.0A) S4M A 301 (-3.1A)	0.29A	3bwcA-4yv2A: 46.7	3bwcA-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_B_SAMB501_0 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	6 / 12	LEU A 59 GLY A 96 ASP A 120 VAL A 123 ASP A 168 GLN A 201	None S4M A 301 ( 4.6A) None S4M A 301 (-4.3A) S4M A 301 (-3.1A) None	1.17A	3bwcB-4yv2A: 45.6	3bwcB-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_B_SAMB501_0 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	LEU A 59 HIS A 74 ILE A 167 ASP A 98 ASP A 168	None S4M A 301 (-4.0A) None S4M A 301 (-3.1A) S4M A 301 (-3.1A)	0.94A	3bwcB-4yv2A: 45.6	3bwcB-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_B_SAMB501_0 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	12 / 12	LEU A 59 TYR A 73 HIS A 74 ILE A 94 GLY A 95 ASP A 98 ILE A 119 ASP A 120 VAL A 123 GLY A 150 ASP A 168 GLN A 201	None S4M A 301 (-4.4A) S4M A 301 (-4.0A) None S4M A 301 (-3.5A) S4M A 301 (-3.1A) S4M A 301 (-3.9A) None S4M A 301 (-4.3A) S4M A 301 (-3.6A) S4M A 301 (-3.1A) None	0.45A	3bwcB-4yv2A: 45.6	3bwcB-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_B_SAMB501_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 5	GLN A 40 GLN A 64 ASP A 118 ASP A 149	S4M A 301 (-3.4A) S4M A 301 (-4.2A) S4M A 301 (-3.0A) S4M A 301 (-3.9A)	0.30A	3bwcB-4yv2A: 45.6	3bwcB-4yv2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BWC_B_SAMB501_1 (SPERMIDINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 5	GLN A 64 ASP A 118 ASP A 149 THR A 169	S4M A 301 (-4.2A) S4M A 301 (-3.0A) S4M A 301 (-3.9A) S4M A 301 (-4.7A)	0.86A	3bwcB-4yv2A: 45.6	3bwcB-4yv2A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6M_A_SPMA501_1 (SPERMINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 11	TYR A 73 ASP A 98 ASP A 168 GLN A 201 TYR A 237	S4M A 301 (-4.4A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None	0.79A	3c6mA-4yv2A: 23.2	3c6mA-4yv2A: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6M_B_SPMB501_1 (SPERMINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 9	TYR A 73 ASP A 98 ASP A 168 GLN A 201 TYR A 237	S4M A 301 (-4.4A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None	0.77A	3c6mB-4yv2A: 23.1	3c6mB-4yv2A: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6M_C_SPMC501_1 (SPERMINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 10	TYR A 73 ASP A 98 ASP A 168 GLN A 201 TYR A 237	S4M A 301 (-4.4A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None	0.70A	3c6mC-4yv2A: 23.0	3c6mC-4yv2A: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6M_D_SPMD501_1 (SPERMINE SYNTHASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 10	TYR A 73 ASP A 98 ASP A 168 GLN A 201 TYR A 237	S4M A 301 (-4.4A) S4M A 301 (-3.1A) S4M A 301 (-3.1A) None None	0.76A	3c6mD-4yv2A: 23.2	3c6mD-4yv2A: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D91_B_REMB350_1 (RENIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLN A 133 ASP A 98 GLY A 96 VAL A 65 LEU A 116	None S4M A 301 (-3.1A) S4M A 301 ( 4.6A) None None	1.24A	3d91B-4yv2A: undetectable	3d91B-4yv2A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_A_SAMA500_0 (PCZA361.24)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLY A 100 LEU A 77 LEU A 106 SER A 135 GLY A 95	None None None None S4M A 301 (-3.5A)	1.02A	3g2oA-4yv2A: 12.8	3g2oA-4yv2A: 26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB0_A_DIFA701_1 (LACTOTRANSFERRIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 4	PRO A 52 TYR A 68 GLY A 54 THR A 55	None	1.45A	3ib0A-4yv2A: 1.7	3ib0A-4yv2A: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_B_ACTB1002_0 (PUTATIVE OXIDOREDUCTASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 5	ASP A 118 GLY A 121 VAL A 123 ASP A 120	S4M A 301 (-3.0A) None S4M A 301 (-4.3A) None	1.02A	3vqrB-4yv2A: 3.4	3vqrB-4yv2A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B17_A_SAMA1358_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLY A 95 GLY A 99 GLY A 100 ASP A 118 ASP A 149	S4M A 301 (-3.5A) None None S4M A 301 (-3.0A) S4M A 301 (-3.9A)	0.76A	4b17A-4yv2A: 10.6	4b17A-4yv2A: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_A_SPMA202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 8	ILE A 242 GLU A 203 GLN A 201 ILE A 167	None	0.92A	4mj8A-4yv2A: 2.3	4mj8A-4yv2A: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM9_A_FVXA603_1 (TRANSPORTER)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 11	ASP A 168 TYR A 73 GLY A 99 GLY A 78 ASP A 69	S4M A 301 (-3.1A) S4M A 301 (-4.4A) None None None	1.30A	4mm9A-4yv2A: undetectable	4mm9A-4yv2A: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_A_STRA604_1 (CYTOCHROME P450 21-HYDROXYLASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	VAL A 255 SER A 282 LEU A 245 GLY A 243 LEU A 285	None	1.01A	4y8wA-4yv2A: undetectable	4y8wA-4yv2A: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_B_STRB603_1 (CYTOCHROME P450 21-HYDROXYLASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	VAL A 255 SER A 282 LEU A 245 GLY A 243 LEU A 285	None	1.05A	4y8wB-4yv2A: undetectable	4y8wB-4yv2A: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E72_A_SAMA400_1 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 4	ASP A 168 GLY A 97 ASP A 118 ASP A 149	S4M A 301 (-3.1A) S4M A 301 ( 4.5A) S4M A 301 (-3.0A) S4M A 301 (-3.9A)	1.17A	5e72A-4yv2A: 12.3	5e72A-4yv2A: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_I_Z80I401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 9	PHE A 224 VAL A 255 ASP A 195 ILE A 197	None	0.88A	5lg3I-4yv2A: undetectable	5lg3I-4yv2A: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U6N_A_SALA505_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 8	SER A 84 HIS A 279 PHE A 283 THR A 244	None	1.26A	5u6nA-4yv2A: 3.2	5u6nA-4yv2A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U6N_B_SALB504_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	4 / 6	SER A 84 HIS A 279 PHE A 283 THR A 244	None	1.29A	5u6nB-4yv2A: 3.9	5u6nB-4yv2A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YNI_A_SAMA401_0 (NSP16 PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLY A 95 GLY A 100 ASP A 118 ASP A 149 ASP A 168	S4M A 301 (-3.5A) None S4M A 301 (-3.0A) S4M A 301 (-3.9A) S4M A 301 (-3.1A)	0.64A	5yniA-4yv2A: 8.4	5yniA-4yv2A: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YNM_A_SAMA401_0 (NSP16 PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLY A 95 GLY A 100 ASP A 118 ASP A 149 ASP A 168	S4M A 301 (-3.5A) None S4M A 301 (-3.0A) S4M A 301 (-3.9A) S4M A 301 (-3.1A)	0.66A	5ynmA-4yv2A: 8.4	5ynmA-4yv2A: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_A_ADNA401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	7 / 12	GLN A 40 GLY A 95 ASP A 118 ILE A 119 ASP A 120 VAL A 123 ASP A 149	S4M A 301 (-3.4A) S4M A 301 (-3.5A) S4M A 301 (-3.0A) S4M A 301 (-3.9A) None S4M A 301 (-4.3A) S4M A 301 (-3.9A)	0.51A	6bq4A-4yv2A: 31.7	6bq4A-4yv2A: 13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_B_ADNB401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	7 / 12	GLN A 40 GLY A 95 ASP A 118 ILE A 119 ASP A 120 VAL A 123 ASP A 149	S4M A 301 (-3.4A) S4M A 301 (-3.5A) S4M A 301 (-3.0A) S4M A 301 (-3.9A) None S4M A 301 (-4.3A) S4M A 301 (-3.9A)	0.41A	6bq4B-4yv2A: 31.8	6bq4B-4yv2A: 13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_B_ADNB401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	GLN A 40 GLY A 96 ASP A 118 ASP A 120 VAL A 123	S4M A 301 (-3.4A) S4M A 301 ( 4.6A) S4M A 301 (-3.0A) None S4M A 301 (-4.3A)	1.05A	6bq4B-4yv2A: 31.8	6bq4B-4yv2A: 13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IFT_A_SAMA301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A)	4yv2	SPERMIDINE SYNTHASE, PUTATIVE (Trypanosoma cruzi)	5 / 12	ILE A 94 GLY A 95 GLY A 97 ILE A 119 ASP A 120	None S4M A 301 (-3.5A) S4M A 301 ( 4.5A) S4M A 301 (-3.9A) None	0.61A	6iftA-4yv2A: 9.3	6iftA-4yv2A: 21.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EJ0_A_SAMA301_1","FTSJ","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",3,"ASP A 118;ASP A 149;ASP A 168","S4M A 301 (-3.0A);S4M A 301 (-3.9A);S4M A 301 (-3.1A)","0.79A","1ej0A-4yv2A:11.4","1ej0A-4yv2A:21.92"],["1EKJ_C_ACTC3007_0","BETA-CARBONIC ANHYDRASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"VAL A 234;GLY A 243;GLN A 201;TYR A  73","None;None;None;S4M A 301 (-4.4A)","1.25A","1ekjC-4yv2A:undetectable;1ekjD-4yv2A:undetectable","1ekjC-4yv2A:22.22;1ekjD-4yv2A:22.22"],["1N2X_B_SAMB402_0","S-ADENOSYL-METHYLTRANSFERASE MRAW","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLY A  97;GLY A  99;GLY A 100;ASP A 120;VAL A 123","S4M A 301 ( 4.5A);None;None;None;S4M A 301 (-4.3A)","0.68A","1n2xB-4yv2A:13.4","1n2xB-4yv2A:22.51"],["1QAO_A_SAMA245_0","ERMC' METHYLTRANSFERASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLY A  95;GLY A  97;ILE A 119;ASP A 120;ASP A 149","S4M A 301 (-3.5A);S4M A 301 ( 4.5A);S4M A 301 (-3.9A);None;S4M A 301 (-3.9A)","0.71A","1qaoA-4yv2A:9.2","1qaoA-4yv2A:21.02"],["1SQ5_B_PAUB6003_0","PANTOTHENATE KINASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"ASP A  98;GLY A  95;HIS A  74;LEU A 116;ILE A 167","S4M A 301 (-3.1A);S4M A 301 (-3.5A);S4M A 301 (-4.0A);None;None","1.24A","1sq5B-4yv2A:1.0","1sq5B-4yv2A:20.35"],["1SQF_A_SAMA430_0","SUN PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",6,"GLY A  99;GLY A 100;ILE A 119;ASP A 120;ASP A 149;GLY A 150","None;None;S4M A 301 (-3.9A);None;S4M A 301 (-3.9A);S4M A 301 (-3.6A)","0.47A","1sqfA-4yv2A:9.5","1sqfA-4yv2A:22.15"],["1TW4_A_CHDA130_1","FATTY ACID-BINDING PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",3,"TYR A 162;ARG A 155;GLN A 156","None","0.93A","1tw4A-4yv2A:undetectable","1tw4A-4yv2A:20.34"],["2QB4_A_DSMA802_1","TRANSPORTER","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"ILE A 197;ARG A 220;PHE A 224;ILE A 219","None","1.00A","2qb4A-4yv2A:undetectable","2qb4A-4yv2A:21.08"],["2UZ2_A_ACTA1123_0","XENAVIDIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"ASN A 200;LEU A 245;TYR A 185;VAL A 227","None","1.11A","2uz2A-4yv2A:undetectable","2uz2A-4yv2A:15.79"],["2Y7W_C_SALC1300_1","LYSR-TYPE REGULATORY PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"THR A 169;ILE A  94;GLY A  95;ILE A 119","S4M A 301 (-4.7A);None;S4M A 301 (-3.5A);S4M A 301 (-3.9A)","0.70A","2y7wC-4yv2A:undetectable","2y7wC-4yv2A:19.81"],["3B7P_A_SPMA501_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",8,"GLN A  64;TYR A  73;HIS A  74;ASP A  98;ASP A 168;GLN A 201;TYR A 237;PRO A 238","S4M A 301 (-4.2A);S4M A 301 (-4.4A);S4M A 301 (-4.0A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None;None","0.76A","3b7pA-4yv2A:38.0","3b7pA-4yv2A:42.18"],["3B7P_A_SPMA501_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",8,"GLN A  64;TYR A  73;HIS A  74;ASP A  98;ASP A 168;TYR A 237;PRO A 238;ILE A 242","S4M A 301 (-4.2A);S4M A 301 (-4.4A);S4M A 301 (-4.0A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None;None","0.57A","3b7pA-4yv2A:38.0","3b7pA-4yv2A:42.18"],["3B7P_A_SPMA501_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLN A 201;HIS A  74;ASP A 168;TYR A 237;PRO A 238","None;S4M A 301 (-4.0A);S4M A 301 (-3.1A);None;None","1.33A","3b7pA-4yv2A:38.0","3b7pA-4yv2A:42.18"],["3B7P_B_SPMB502_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",8,"GLN A  64;TYR A  73;HIS A  74;ASP A  98;ASP A 168;GLN A 201;TYR A 237;PRO A 238","S4M A 301 (-4.2A);S4M A 301 (-4.4A);S4M A 301 (-4.0A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None;None","0.76A","3b7pB-4yv2A:38.4","3b7pB-4yv2A:42.18"],["3B7P_B_SPMB502_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",8,"GLN A  64;TYR A  73;HIS A  74;ASP A  98;ASP A 168;TYR A 237;PRO A 238;ILE A 242","S4M A 301 (-4.2A);S4M A 301 (-4.4A);S4M A 301 (-4.0A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None;None","0.59A","3b7pB-4yv2A:38.4","3b7pB-4yv2A:42.18"],["3B7P_B_SPMB502_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLN A 201;HIS A  74;ASP A 168;TYR A 237;PRO A 238","None;S4M A 301 (-4.0A);S4M A 301 (-3.1A);None;None","1.40A","3b7pB-4yv2A:38.4","3b7pB-4yv2A:42.18"],["3B7P_C_SPMC503_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",10,"GLN A  64;TYR A  73;HIS A  74;ASP A  98;ASP A 168;GLU A 203;SER A 204;TYR A 237;PRO A 238;ILE A 242","S4M A 301 (-4.2A);S4M A 301 (-4.4A);S4M A 301 (-4.0A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None;None;None;None","0.63A","3b7pC-4yv2A:38.3","3b7pC-4yv2A:42.18"],["3B7P_C_SPMC503_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLN A 201;HIS A  74;ASP A 168;TYR A 237;PRO A 238","None;S4M A 301 (-4.0A);S4M A 301 (-3.1A);None;None","1.29A","3b7pC-4yv2A:38.3","3b7pC-4yv2A:42.18"],["3BWC_A_SAMA501_0","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",6,"GLN A  40;GLY A  96;ASP A 120;VAL A 123;THR A 169;GLN A 201","S4M A 301 (-3.4A);S4M A 301 ( 4.6A);None;S4M A 301 (-4.3A);S4M A 301 (-4.7A);None","1.09A","3bwcA-4yv2A:46.7","3bwcA-4yv2A:100.00"],["3BWC_A_SAMA501_0","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",12,"GLN A  40;TYR A  73;HIS A  74;ILE A  94;GLY A  95;ILE A 119;ASP A 120;VAL A 123;ASP A 149;GLY A 150;THR A 169;GLN A 201","S4M A 301 (-3.4A);S4M A 301 (-4.4A);S4M A 301 (-4.0A);None;S4M A 301 (-3.5A);S4M A 301 (-3.9A);None;S4M A 301 (-4.3A);S4M A 301 (-3.9A);S4M A 301 (-3.6A);S4M A 301 (-4.7A);None","0.49A","3bwcA-4yv2A:46.7","3bwcA-4yv2A:100.00"],["3BWC_A_SAMA501_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"LEU A  59;GLN A  64;ASP A 118;ASP A 168","None;S4M A 301 (-4.2A);S4M A 301 (-3.0A);S4M A 301 (-3.1A)","0.29A","3bwcA-4yv2A:46.7","3bwcA-4yv2A:100.00"],["3BWC_B_SAMB501_0","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",6,"LEU A  59;GLY A  96;ASP A 120;VAL A 123;ASP A 168;GLN A 201","None;S4M A 301 ( 4.6A);None;S4M A 301 (-4.3A);S4M A 301 (-3.1A);None","1.17A","3bwcB-4yv2A:45.6","3bwcB-4yv2A:100.00"],["3BWC_B_SAMB501_0","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"LEU A  59;HIS A  74;ILE A 167;ASP A  98;ASP A 168","None;S4M A 301 (-4.0A);None;S4M A 301 (-3.1A);S4M A 301 (-3.1A)","0.94A","3bwcB-4yv2A:45.6","3bwcB-4yv2A:100.00"],["3BWC_B_SAMB501_0","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",12,"LEU A  59;TYR A  73;HIS A  74;ILE A  94;GLY A  95;ASP A  98;ILE A 119;ASP A 120;VAL A 123;GLY A 150;ASP A 168;GLN A 201","None;S4M A 301 (-4.4A);S4M A 301 (-4.0A);None;S4M A 301 (-3.5A);S4M A 301 (-3.1A);S4M A 301 (-3.9A);None;S4M A 301 (-4.3A);S4M A 301 (-3.6A);S4M A 301 (-3.1A);None","0.45A","3bwcB-4yv2A:45.6","3bwcB-4yv2A:100.00"],["3BWC_B_SAMB501_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"GLN A  40;GLN A  64;ASP A 118;ASP A 149","S4M A 301 (-3.4A);S4M A 301 (-4.2A);S4M A 301 (-3.0A);S4M A 301 (-3.9A)","0.30A","3bwcB-4yv2A:45.6","3bwcB-4yv2A:100.00"],["3BWC_B_SAMB501_1","SPERMIDINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"GLN A  64;ASP A 118;ASP A 149;THR A 169","S4M A 301 (-4.2A);S4M A 301 (-3.0A);S4M A 301 (-3.9A);S4M A 301 (-4.7A)","0.86A","3bwcB-4yv2A:45.6","3bwcB-4yv2A:100.00"],["3C6M_A_SPMA501_1","SPERMINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"TYR A  73;ASP A  98;ASP A 168;GLN A 201;TYR A 237","S4M A 301 (-4.4A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None","0.79A","3c6mA-4yv2A:23.2","3c6mA-4yv2A:24.40"],["3C6M_B_SPMB501_1","SPERMINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"TYR A  73;ASP A  98;ASP A 168;GLN A 201;TYR A 237","S4M A 301 (-4.4A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None","0.77A","3c6mB-4yv2A:23.1","3c6mB-4yv2A:24.40"],["3C6M_C_SPMC501_1","SPERMINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"TYR A  73;ASP A  98;ASP A 168;GLN A 201;TYR A 237","S4M A 301 (-4.4A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None","0.70A","3c6mC-4yv2A:23.0","3c6mC-4yv2A:24.40"],["3C6M_D_SPMD501_1","SPERMINE SYNTHASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"TYR A  73;ASP A  98;ASP A 168;GLN A 201;TYR A 237","S4M A 301 (-4.4A);S4M A 301 (-3.1A);S4M A 301 (-3.1A);None;None","0.76A","3c6mD-4yv2A:23.2","3c6mD-4yv2A:24.40"],["3D91_B_REMB350_1","RENIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLN A 133;ASP A  98;GLY A  96;VAL A  65;LEU A 116","None;S4M A 301 (-3.1A);S4M A 301 ( 4.6A);None;None","1.24A","3d91B-4yv2A:undetectable","3d91B-4yv2A:22.28"],["3G2O_A_SAMA500_0","PCZA361.24","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLY A 100;LEU A  77;LEU A 106;SER A 135;GLY A  95","None;None;None;None;S4M A 301 (-3.5A)","1.02A","3g2oA-4yv2A:12.8","3g2oA-4yv2A:26.15"],["3IB0_A_DIFA701_1","LACTOTRANSFERRIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"PRO A  52;TYR A  68;GLY A  54;THR A  55","None","1.45A","3ib0A-4yv2A:1.7","3ib0A-4yv2A:21.77"],["3VQR_B_ACTB1002_0","PUTATIVE OXIDOREDUCTASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"ASP A 118;GLY A 121;VAL A 123;ASP A 120","S4M A 301 (-3.0A);None;S4M A 301 (-4.3A);None","1.02A","3vqrB-4yv2A:3.4","3vqrB-4yv2A:21.43"],["4B17_A_SAMA1358_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLY A  95;GLY A  99;GLY A 100;ASP A 118;ASP A 149","S4M A 301 (-3.5A);None;None;S4M A 301 (-3.0A);S4M A 301 (-3.9A)","0.76A","4b17A-4yv2A:10.6","4b17A-4yv2A:21.20"],["4MJ8_A_SPMA202_1","SPERMIDINE N1-ACETYLTRANSFERASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"ILE A 242;GLU A 203;GLN A 201;ILE A 167","None","0.92A","4mj8A-4yv2A:2.3","4mj8A-4yv2A:19.08"],["4MM9_A_FVXA603_1","TRANSPORTER","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"ASP A 168;TYR A  73;GLY A  99;GLY A  78;ASP A  69","S4M A 301 (-3.1A);S4M A 301 (-4.4A);None;None;None","1.30A","4mm9A-4yv2A:undetectable","4mm9A-4yv2A:21.28"],["4Y8W_A_STRA604_1","CYTOCHROME P450 21-HYDROXYLASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"VAL A 255;SER A 282;LEU A 245;GLY A 243;LEU A 285","None","1.01A","4y8wA-4yv2A:undetectable","4y8wA-4yv2A:20.73"],["4Y8W_B_STRB603_1","CYTOCHROME P450 21-HYDROXYLASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"VAL A 255;SER A 282;LEU A 245;GLY A 243;LEU A 285","None","1.05A","4y8wB-4yv2A:undetectable","4y8wB-4yv2A:20.73"],["5E72_A_SAMA400_1","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"ASP A 168;GLY A  97;ASP A 118;ASP A 149","S4M A 301 (-3.1A);S4M A 301 ( 4.5A);S4M A 301 (-3.0A);S4M A 301 (-3.9A)","1.17A","5e72A-4yv2A:12.3","5e72A-4yv2A:22.40"],["5LG3_I_Z80I401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"PHE A 224;VAL A 255;ASP A 195;ILE A 197","None","0.88A","5lg3I-4yv2A:undetectable","5lg3I-4yv2A:21.29"],["5U6N_A_SALA505_1","UDP-GLYCOSYLTRANSFERASE 74F2","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"SER A  84;HIS A 279;PHE A 283;THR A 244","None","1.26A","5u6nA-4yv2A:3.2","5u6nA-4yv2A:19.82"],["5U6N_B_SALB504_1","UDP-GLYCOSYLTRANSFERASE 74F2","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",4,"SER A  84;HIS A 279;PHE A 283;THR A 244","None","1.29A","5u6nB-4yv2A:3.9","5u6nB-4yv2A:19.82"],["5YNI_A_SAMA401_0","NSP16 PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLY A  95;GLY A 100;ASP A 118;ASP A 149;ASP A 168","S4M A 301 (-3.5A);None;S4M A 301 (-3.0A);S4M A 301 (-3.9A);S4M A 301 (-3.1A)","0.64A","5yniA-4yv2A:8.4","5yniA-4yv2A:23.30"],["5YNM_A_SAMA401_0","NSP16 PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLY A  95;GLY A 100;ASP A 118;ASP A 149;ASP A 168","S4M A 301 (-3.5A);None;S4M A 301 (-3.0A);S4M A 301 (-3.9A);S4M A 301 (-3.1A)","0.66A","5ynmA-4yv2A:8.4","5ynmA-4yv2A:23.30"],["6BQ4_A_ADNA401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",7,"GLN A  40;GLY A  95;ASP A 118;ILE A 119;ASP A 120;VAL A 123;ASP A 149","S4M A 301 (-3.4A);S4M A 301 (-3.5A);S4M A 301 (-3.0A);S4M A 301 (-3.9A);None;S4M A 301 (-4.3A);S4M A 301 (-3.9A)","0.51A","6bq4A-4yv2A:31.7","6bq4A-4yv2A:13.51"],["6BQ4_B_ADNB401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",7,"GLN A  40;GLY A  95;ASP A 118;ILE A 119;ASP A 120;VAL A 123;ASP A 149","S4M A 301 (-3.4A);S4M A 301 (-3.5A);S4M A 301 (-3.0A);S4M A 301 (-3.9A);None;S4M A 301 (-4.3A);S4M A 301 (-3.9A)","0.41A","6bq4B-4yv2A:31.8","6bq4B-4yv2A:13.51"],["6BQ4_B_ADNB401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"GLN A  40;GLY A  96;ASP A 118;ASP A 120;VAL A 123","S4M A 301 (-3.4A);S4M A 301 ( 4.6A);S4M A 301 (-3.0A);None;S4M A 301 (-4.3A)","1.05A","6bq4B-4yv2A:31.8","6bq4B-4yv2A:13.51"],["6IFT_A_SAMA301_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A","4yv2","SPERMIDINE SYNTHASE, PUTATIVE","Trypanosoma cruzi",5,"ILE A  94;GLY A  95;GLY A  97;ILE A 119;ASP A 120","None;S4M A 301 (-3.5A);S4M A 301 ( 4.5A);S4M A 301 (-3.9A);None","0.61A","6iftA-4yv2A:9.3","6iftA-4yv2A:21.65"]]