SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ywc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 9 THR A  68
GLY A  99
GLY A 199
LEU A 200
GLU A 100
 None
 1.29A 1jhoA-4ywcA:
undetectable		 1jhoA-4ywcA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 9 THR A  68
GLY A  99
GLY A 199
LEU A 200
GLU A 100
 None
 1.32A 1l5lA-4ywcA:
undetectable		 1l5lA-4ywcA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 12 ALA A 192
GLY A 188
GLU A 214
LEU A 165
PRO A 166
 None
 1.06A 1mj2A-4ywcA:
undetectable
1mj2B-4ywcA:
undetectable		 1mj2A-4ywcA:
15.97
1mj2B-4ywcA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 11 GLU A 214
LEU A 165
PRO A 166
ALA A 192
GLY A 188
 None
 1.13A 1mjqA-4ywcA:
undetectable
1mjqB-4ywcA:
undetectable		 1mjqA-4ywcA:
15.97
1mjqB-4ywcA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 10 GLU A 214
LEU A 165
PRO A 166
ALA A 192
GLY A 188
 None
 1.11A 1mjqC-4ywcA:
undetectable
1mjqD-4ywcA:
undetectable		 1mjqC-4ywcA:
15.97
1mjqD-4ywcA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 10 GLU A 214
LEU A 165
PRO A 166
ALA A 192
GLY A 188
 None
 1.13A 1mjqG-4ywcA:
undetectable
1mjqH-4ywcA:
undetectable		 1mjqG-4ywcA:
15.97
1mjqH-4ywcA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 11 GLU A 214
LEU A 165
PRO A 166
ALA A 192
GLY A 188
 None
 1.11A 1mjqI-4ywcA:
undetectable
1mjqJ-4ywcA:
undetectable		 1mjqI-4ywcA:
15.97
1mjqJ-4ywcA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		4 / 6 ILE A  71
MET A 203
THR A 202
LEU A 200
 None
 1.01A 2einN-4ywcA:
undetectable
2einW-4ywcA:
undetectable		 2einN-4ywcA:
17.12
2einW-4ywcA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		4 / 6 ILE A  71
MET A 203
THR A 202
LEU A 200
 None
 1.02A 3ag1N-4ywcA:
undetectable
3ag1W-4ywcA:
undetectable		 3ag1N-4ywcA:
17.12
3ag1W-4ywcA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		4 / 4 LEU A  90
ASP A  94
VAL A 213
THR A 208
 None
 1.31A 3cyxB-4ywcA:
undetectable		 3cyxB-4ywcA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		4 / 6 PHE A  72
GLY A 211
THR A 208
GLN A 209
 None
 1.17A 6ag0A-4ywcA:
undetectable		 6ag0A-4ywcA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 4ywc TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		4 / 6 PHE A  72
GLY A 211
THR A 208
GLN A 209
 None
 1.18A 6ag0C-4ywcA:
undetectable		 6ag0C-4ywcA:
16.36