SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ywk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		4 / 7 PHE A  95
ALA A  71
PHE A  10
PHE A  13
 None
 1.23A 1lqtA-4ywkA:
undetectable		 1lqtA-4ywkA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		4 / 7 PHE A  95
ALA A  71
PHE A  10
PHE A  13
 None
 1.23A 1lquA-4ywkA:
undetectable		 1lquA-4ywkA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		5 / 11 ASP A 106
ILE A 203
VAL A 118
GLY A 120
ILE A 121
 None
 0.82A 3ebzB-4ywkA:
undetectable		 3ebzB-4ywkA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		4 / 6 GLY A  67
VAL A  60
PRO A  64
GLY A 225
 None
 0.77A 4dxuA-4ywkA:
undetectable		 4dxuA-4ywkA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		4 / 7 GLY A  67
VAL A  60
PRO A  64
GLY A 225
 None
 0.77A 4forA-4ywkA:
undetectable		 4forA-4ywkA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		3 / 3 ARG A  94
ILE A  44
PHE A  95
 None
 0.69A 5kirA-4ywkA:
undetectable		 5kirA-4ywkA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		6 / 12 GLY A 225
VAL A 221
ILE A 187
GLY A 205
ILE A 206
VAL A 214
 None
 1.16A 6dj1B-4ywkA:
undetectable		 6dj1B-4ywkA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 4ywk CELL DIVISION
CONTROL PROTEIN 21
(Pyrococcus
furiosus) 		6 / 12 GLY A 225
VAL A 221
ILE A 187
GLY A 205
ILE A 206
VAL A 214
 None
 1.14A 6dj2B-4ywkA:
undetectable		 6dj2B-4ywkA:
17.82