SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ywn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 4ywn NADH-FMN
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 8 ALA A  39
VAL A  57
PHE A  55
THR A  42
 None
 0.88A 2kotB-4ywnA:
undetectable		 2kotB-4ywnA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4ywn NADH-FMN
OXIDOREDUCTASE
(Mycobacterium
avium) 		4 / 7 ASN A 140
ALA A 122
SER A 121
VAL A  53
 None
 1.02A 4ijiH-4ywnA:
undetectable		 4ijiH-4ywnA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4ywn NADH-FMN
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 VAL A  53
LEU A 137
ILE A  75
GLY A  74
LEU A  38
 None
 1.08A 4y8wA-4ywnA:
undetectable		 4y8wA-4ywnA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4ywn NADH-FMN
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 9 THR A 102
ILE A 112
THR A  63
LEU A  67
LEU A  73
 None
 1.37A 4ze0A-4ywnA:
undetectable		 4ze0A-4ywnA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ywn NADH-FMN
OXIDOREDUCTASE
(Mycobacterium
avium) 		5 / 12 LEU A  67
GLY A  74
SER A  76
PHE A  55
VAL A  57
 None
 1.21A 6a94A-4ywnA:
undetectable		 6a94A-4ywnA:
20.33