SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yx5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_D_SALD1300_1 (LYSR-TYPE REGULATORY PROTEIN)	4yx5	SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO (Salmonella enterica)	5 / 12	ILE A 29 GLY B 50 LEU B 49 PHE B 9 ILE B 42	None	1.14A	2y7kD-4yx5A: undetectable	2y7kD-4yx5A: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_D_VD3D2001_1 (VITAMIN D HYDROXYLASE)	4yx5	SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO (Salmonella enterica)	5 / 12	ILE A 61 LEU B 32 ASN B 51 ILE A 16 ALA A 42	None	1.05A	3a50D-4yx5A: undetectable	3a50D-4yx5A: 11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_D_VD3D2001_1 (VITAMIN D HYDROXYLASE)	4yx5	SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO (Salmonella enterica)	5 / 12	PRO B 33 ILE A 61 LEU B 32 ILE A 16 ALA A 42	None	1.01A	3a50D-4yx5B: undetectable	3a50D-4yx5B: 13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O96_B_SAMB501_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	4yx5	SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO (Salmonella enterica; Salmonella enterica)	5 / 9	ARG B 13 LEU A 35 ILE B 65 GLY B 52 LEU B 49	None	0.96A	5o96A-4yx5B: undetectable 5o96B-4yx5B: undetectable	5o96A-4yx5B: 14.83 5o96B-4yx5B: 14.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y7K_D_SALD1300_1","LYSR-TYPE REGULATORY PROTEIN","4yx5","SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO","Salmonella enterica",5,"ILE A  29;GLY B  50;LEU B  49;PHE B   9;ILE B  42","None","1.14A","2y7kD-4yx5A:undetectable","2y7kD-4yx5A:18.06"],["3A50_D_VD3D2001_1","VITAMIN D HYDROXYLASE","4yx5","SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO","Salmonella enterica",5,"ILE A  61;LEU B  32;ASN B  51;ILE A  16;ALA A  42","None","1.05A","3a50D-4yx5A:undetectable","3a50D-4yx5A:11.11"],["3A50_D_VD3D2001_1","VITAMIN D HYDROXYLASE","4yx5","SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO","Salmonella enterica",5,"PRO B  33;ILE A  61;LEU B  32;ILE A  16;ALA A  42","None","1.01A","3a50D-4yx5B:undetectable","3a50D-4yx5B:13.01"],["5O96_B_SAMB501_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","4yx5","SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO;SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAO","Salmonella enterica;Salmonella enterica",5,"ARG B  13;LEU A  35;ILE B  65;GLY B  52;LEU B  49","None","0.96A","5o96A-4yx5B:undetectable;5o96B-4yx5B:undetectable","5o96A-4yx5B:14.83;5o96B-4yx5B:14.83"]]