SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 12 ALA C 162
PHE C 186
LEU C 166
ALA C 163
ILE C 111
 None
 1.01A 2aclA-4yx7C:
undetectable
2aclE-4yx7C:
undetectable		 2aclA-4yx7C:
23.90
2aclE-4yx7C:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		3 / 3 ALA C 193
THR C 184
PHE C  32
 None
 0.78A 2c6nB-4yx7C:
undetectable		 2c6nB-4yx7C:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		4 / 8 THR C  67
TYR C  58
ILE C  50
SER C  69
 None
 0.93A 2xytH-4yx7C:
undetectable		 2xytH-4yx7C:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		4 / 7 THR C  67
TYR C  58
ILE C  50
SER C  69
 None
 0.94A 2xytI-4yx7C:
undetectable		 2xytI-4yx7C:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 9 ALA C 107
ASP C 103
GLY C   1
ALA C 130
ILE C 133
 None
 1.09A 3ektB-4yx7C:
undetectable		 3ektB-4yx7C:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 12 LEU C 132
ALA C 107
ASP C 103
GLY C   1
ILE C 133
 None
 1.02A 4jecB-4yx7C:
undetectable		 4jecB-4yx7C:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 11 LEU C 132
ALA C 107
ASP C 103
GLY C   1
ILE C 133
 None
 0.94A 4njtC-4yx7C:
undetectable		 4njtC-4yx7C:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 12 VAL C 136
GLU C 141
ALA C 107
ARG C 113
LEU C 112
 None
 1.19A 5nd2B-4yx7C:
undetectable		 5nd2B-4yx7C:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 12 VAL C 136
GLU C 141
ALA C 107
ARG C 113
LEU C 112
 None
 1.20A 5nd7B-4yx7C:
undetectable		 5nd7B-4yx7C:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 12 LEU C 132
ALA C 107
ASP C 103
GLY C   1
ILE C 133
 None
 0.99A 6dgxB-4yx7C:
undetectable		 6dgxB-4yx7C:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 4yx7 OXYGEN-REGULATED
INVASION PROTEIN
ORGB,ENDOLYSIN
(Escherichia
virus
T4;
Salmonella
enterica) 		5 / 12 LEU C 132
ALA C 107
ASP C 103
GLY C   1
ILE C 133
 None
 1.03A 6dh6B-4yx7C:
undetectable		 6dh6B-4yx7C:
18.75