SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 4yxf MUPS
(Pseudomonas
fluorescens) 		3 / 3 LEU A 233
SER A 195
ASN A 150
 None
 0.53A 1bx4A-4yxfA:
3.3		 1bx4A-4yxfA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 11 LEU A 132
LEU A 130
ALA A 168
ALA A 172
MET A 173
 None
 1.33A 1iiuA-4yxfA:
undetectable		 1iiuA-4yxfA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 LEU A 132
LEU A 130
ALA A 168
ALA A 172
MET A 173
 None
 1.31A 1kt4A-4yxfA:
undetectable		 1kt4A-4yxfA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 LEU A 132
LEU A 130
ALA A 168
ALA A 172
MET A 173
 None
 1.28A 1kt5A-4yxfA:
undetectable		 1kt5A-4yxfA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 ILE A 249
GLY A 146
ILE A  25
TYR A  46
ILE A  24
 None
 0.77A 3pwwA-4yxfA:
undetectable		 3pwwA-4yxfA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 4yxf MUPS
(Pseudomonas
fluorescens) 		3 / 3 ASP A 239
ARG A 240
ASP A 232
 None
 0.81A 4fp9D-4yxfA:
5.2		 4fp9D-4yxfA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4yxf MUPS
(Pseudomonas
fluorescens) 		6 / 12 ILE A  25
VAL A  85
LEU A 132
ALA A 138
LEU A 140
LEU A  95
 None
 1.37A 4m11B-4yxfA:
undetectable		 4m11B-4yxfA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4yxf MUPS
(Pseudomonas
fluorescens) 		4 / 4 GLY A 146
VAL A 148
PHE A  84
ILE A  25
 None
 1.03A 4xv2B-4yxfA:
undetectable		 4xv2B-4yxfA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		3 / 3 ASP A 239
ARG A 240
ASP A 232
 None
 0.89A 5zvgB-4yxfA:
5.5		 5zvgB-4yxfA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 GLU A  89
LEU A 180
LEU A 176
ALA A 138
LEU A 184
 None
 0.95A 6ew0B-4yxfA:
6.2		 6ew0B-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 VAL A  85
GLU A  89
LEU A 180
LEU A 176
LEU A 184
 None
 1.13A 6ew0B-4yxfA:
6.2		 6ew0B-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 GLU A  89
LEU A 180
LEU A 176
ALA A 138
LEU A 184
 None
 0.95A 6ew0D-4yxfA:
6.2		 6ew0D-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 VAL A  85
GLU A  89
LEU A 180
LEU A 176
LEU A 184
 None
 1.12A 6ew0D-4yxfA:
6.2		 6ew0D-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 GLU A  89
LEU A 180
LEU A 176
ALA A 138
LEU A 184
 None
 0.95A 6ew0H-4yxfA:
2.4		 6ew0H-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 VAL A  85
GLU A  89
LEU A 180
LEU A 176
LEU A 184
 None
 1.13A 6ew0H-4yxfA:
2.4		 6ew0H-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 GLU A  89
LEU A 180
LEU A 176
ALA A 138
LEU A 184
 None
 0.95A 6ew0I-4yxfA:
undetectable		 6ew0I-4yxfA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 4yxf MUPS
(Pseudomonas
fluorescens) 		5 / 12 VAL A  85
GLU A  89
LEU A 180
LEU A 176
LEU A 184
 None
 1.12A 6ew0I-4yxfA:
undetectable		 6ew0I-4yxfA:
17.25