SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yyb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 4yyb HA1
(Influenza
A
virus) 		5 / 12 GLY A 247
SER A 212
ALA A 210
LEU A 151
VAL A 125
 None
 1.22A 1i9gA-4yybA:
undetectable		 1i9gA-4yybA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4yyb HA1
(Influenza
A
virus) 		4 / 6 ILE A  61
GLY A  63
ILE A 228
LEU A 101
 None
 0.78A 4o8fB-4yybA:
undetectable		 4o8fB-4yybA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4yyb HA1
(Influenza
A
virus) 		5 / 12 LEU A  62
ILE A 228
HIS A 182
VAL A 200
LEU A  98
 None
 1.39A 6djzB-4yybA:
undetectable		 6djzB-4yybA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 4yyb HA1
(Influenza
A
virus) 		4 / 4 GLN A  15
THR A  14
HIS A   8
LEU A 320
 NAG  A 601 ( 3.1A)
None
None
None
 1.42A 6f3nB-4yybA:
undetectable		 6f3nB-4yybA:
19.67