SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4yz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 4yz6 TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 12 GLY A 195
ALA A 192
PHE A 159
LEU A 178
GLU A 214
 None
 1.24A 5hw4A-4yz6A:
undetectable		 5hw4A-4yz6A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 4yz6 TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		5 / 11 GLY A 195
ALA A 192
PHE A 159
LEU A 178
GLU A 214
 None
 1.23A 5hw4B-4yz6A:
undetectable		 5hw4B-4yz6A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4yz6 TRANSCRIPTION FACTOR
MYC3
(Arabidopsis
thaliana) 		3 / 3 HIS A 117
GLU A 114
TRP A 149
 None
 0.97A 5odrD-4yz6A:
undetectable		 5odrD-4yz6A:
20.39