SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 6 LEU H  79
LEU H   4
MET H  34
GLU H  35
 None
 1.26A 2kuhA-4z0bH:
undetectable		 2kuhA-4z0bH:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 4 ALA H  49
TYR H  50
ALA H  61
TYR H  59
 None
 1.24A 2wlkA-4z0bH:
2.5
2wlkB-4z0bH:
2.1		 2wlkA-4z0bH:
20.33
2wlkB-4z0bH:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 VAL H 191
SER H 192
THR H 195
 None
 0.31A 4luhA-4z0bH:
undetectable		 4luhA-4z0bH:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 8 MET H 109
GLU H  35
TYR H  95
TYR H  80
 None
 1.21A 4mj8A-4z0bH:
undetectable
4mj8C-4z0bH:
undetectable		 4mj8A-4z0bH:
17.11
4mj8C-4z0bH:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 211
ALA H 206
VAL H 205
 None
 0.62A 4o2bA-4z0bH:
undetectable		 4o2bA-4z0bH:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 211
ALA H 206
VAL H 205
 None
 0.56A 5eypA-4z0bH:
undetectable		 5eypA-4z0bH:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 5 SER H 192
SER H 193
SER H 194
SER H 142
 None
 0.88A 5hswA-4z0bH:
undetectable		 5hswA-4z0bH:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 5 TYR H  95
GLY H 115
THR H 116
GLY H 170
 None
 0.92A 5jlcA-4z0bH:
undetectable		 5jlcA-4z0bH:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.71A 5jsdA-4z0bH:
undetectable		 5jsdA-4z0bH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.72A 5jsdB-4z0bH:
undetectable		 5jsdB-4z0bH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.71A 5jsdC-4z0bH:
undetectable		 5jsdC-4z0bH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.74A 5jseA-4z0bH:
2.4		 5jseA-4z0bH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.73A 5jseB-4z0bH:
undetectable		 5jseB-4z0bH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.73A 5jseC-4z0bH:
2.7		 5jseC-4z0bH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 211
ALA H 206
VAL H 205
 None
 0.51A 5xiwC-4z0bH:
undetectable		 5xiwC-4z0bH:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4z0b ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 LYS H 124
SER H 121
SER H 122
 None
 1.02A 6gbfA-4z0bH:
undetectable		 6gbfA-4z0bH:
20.48