SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z1o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  90
LEU A  47
SER A 128
ALA A 121
ALA A  96
 None
None
None
None
PRP  A 201 ( 4.6A)
 0.96A 2br4C-4z1oA:
3.9		 2br4C-4z1oA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		3 / 3 ARG A  65
GLU A 100
THR A 101
 PRP  A 201 (-2.8A)
None
PRP  A 201 (-3.5A)
 0.62A 3v4tA-4z1oA:
undetectable		 3v4tA-4z1oA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 VAL A  92
LEU A 122
ALA A  15
LEU A  50
LEU A  47
 None
 1.16A 4i1rA-4z1oA:
undetectable		 4i1rA-4z1oA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		3 / 3 TYR A  64
ARG A  77
LYS A  62
 None
 1.17A 4wq5B-4z1oA:
undetectable		 4wq5B-4z1oA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 PRO A 114
ILE A  59
VAL A  32
LEU A  37
SER A 106
 None
 1.13A 6b52A-4z1oA:
undetectable		 6b52A-4z1oA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 PRO A 114
ILE A  59
VAL A  32
VAL A  89
SER A 106
 None
 1.20A 6b52A-4z1oA:
undetectable		 6b52A-4z1oA:
20.62