SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.13A 1dz4A-4z23A:
undetectable		 1dz4A-4z23A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.11A 1dz4B-4z23A:
undetectable		 1dz4B-4z23A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.16A 1dz9A-4z23A:
undetectable		 1dz9A-4z23A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 LEU A 281
PRO A 173
VAL A 208
TRP A 206
 None
 0.92A 1hrkA-4z23A:
undetectable		 1hrkA-4z23A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 LEU A 281
PRO A 173
VAL A 208
TRP A 206
 None
 0.89A 1hrkB-4z23A:
undetectable		 1hrkB-4z23A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ALA A 210
VAL A 208
TRP A 206
 None
 0.73A 1kqeA-4z23A:
undetectable
1kqeE-4z23A:
undetectable		 1kqeA-4z23A:
3.74
1kqeE-4z23A:
3.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ALA A 210
VAL A 208
TRP A 206
 None
 0.77A 1kqeB-4z23A:
undetectable
1kqeD-4z23A:
undetectable		 1kqeB-4z23A:
3.74
1kqeD-4z23A:
3.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		3 / 3 TRP A 206
ALA A 210
VAL A 208
 None
 0.76A 1kqeB-4z23A:
undetectable
1kqeD-4z23A:
undetectable		 1kqeB-4z23A:
3.74
1kqeD-4z23A:
3.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		3 / 3 TRP A 206
ALA A 210
VAL A 208
 None
 0.79A 1kqeA-4z23A:
undetectable
1kqeE-4z23A:
undetectable		 1kqeA-4z23A:
3.74
1kqeE-4z23A:
3.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ALA A 210
VAL A 208
TRP A 206
 None
 0.56A 1micA-4z23A:
undetectable
1micB-4z23A:
undetectable		 1micA-4z23A:
5.19
1micB-4z23A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.09A 1o76B-4z23A:
undetectable		 1o76B-4z23A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 5 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.14A 1t88B-4z23A:
undetectable		 1t88B-4z23A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.12A 1uyuA-4z23A:
undetectable		 1uyuA-4z23A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.10A 1uyuB-4z23A:
undetectable		 1uyuB-4z23A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 7 LEU A 281
PRO A 173
VAL A 208
TRP A 206
 None
 0.96A 2hrcA-4z23A:
undetectable		 2hrcA-4z23A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 5 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.14A 2m56A-4z23A:
undetectable		 2m56A-4z23A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.14A 2zawA-4z23A:
undetectable		 2zawA-4z23A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		5 / 11 LEU A  59
ALA A  58
LEU A 170
ASN A 168
ALA A  22
 None
None
None
None
EDO  A 401 (-3.8A)
 1.24A 3e22B-4z23A:
undetectable		 3e22B-4z23A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		5 / 12 TYR A 219
ILE A 243
GLY A 205
LEU A 274
LEU A 281
 None
 1.12A 3em0B-4z23A:
undetectable		 3em0B-4z23A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.08A 3fwgA-4z23A:
undetectable		 3fwgA-4z23A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.09A 3wrhE-4z23A:
undetectable		 3wrhE-4z23A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.08A 3wrjE-4z23A:
undetectable		 3wrjE-4z23A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.12A 4ek1A-4z23A:
undetectable		 4ek1A-4z23A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.14A 4g3rB-4z23A:
undetectable		 4g3rB-4z23A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 6 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.12A 4kkyX-4z23A:
undetectable		 4kkyX-4z23A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 5 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.12A 4l49A-4z23A:
undetectable		 4l49A-4z23A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.06A 4l4dA-4z23A:
undetectable		 4l4dA-4z23A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.09A 4l4eA-4z23A:
undetectable		 4l4eA-4z23A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.07A 4l4fA-4z23A:
undetectable		 4l4fA-4z23A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ASP A  74
LYS A  65
LEU A 135
 None
 0.98A 4ptjA-4z23A:
undetectable		 4ptjA-4z23A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A  59
ALA A  58
LEU A 170
ASN A 168
ALA A  22
 None
None
None
None
EDO  A 401 (-3.8A)
 1.16A 4x1yB-4z23A:
undetectable		 4x1yB-4z23A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 GLY A 291
ALA A 292
ASP A 293
GLY A 254
 None
 0.66A 5kr1B-4z23A:
undetectable		 5kr1B-4z23A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		5 / 12 PHE A 290
VAL A 208
PHE A 312
PHE A 221
VAL A 314
 None
 1.26A 6ap6A-4z23A:
undetectable		 6ap6A-4z23A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		5 / 12 PHE A 290
VAL A 208
PHE A 312
PHE A 221
VAL A 314
 None
 1.25A 6ap6B-4z23A:
undetectable		 6ap6B-4z23A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4z23 CELL WALL SURFACE
ANCHOR PROTEIN
(Streptococcus
agalactiae) 		4 / 8 TYR A 133
LEU A  79
VAL A  75
VAL A 125
 None
 1.09A 6cp4A-4z23A:
undetectable		 6cp4A-4z23A:
20.63